Search Results - "Keith, Johnathan D."

Ivacaftor ameliorates mucus burden, bacterial load, and inflammation in acute but not chronic P. aeruginosa infection in hG551D rats by Keith, Johnathan D, Murphree-Terry, Mikayla, Bollar, Gretchen, Oden, Ashley M, Doty, Ian H, Birket, Susan E

“…Background Newly approved highly effective modulation therapies (HEMT) have been life-changing for people with CF. Although these drugs have resulted in…”
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Development of a Broadly Protective, Self-Adjuvanting Subunit Vaccine to Prevent Infections by Pseudomonas aeruginosa by Das, Sayan, Howlader, Debaki R, Zheng, Qi, Ratnakaram, Siva Sai Kumar, Whittier, Sean K, Lu, Ti, Keith, Johnathan D, Picking, William D, Birket, Susan E, Picking, Wendy L

“…Infections caused by the opportunistic pathogen can be difficult to treat due to innate and acquired antibiotic resistance and this is exacerbated by the…”
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Muc5b Contributes to Mucus Abnormality in Rat Models of Cystic Fibrosis by Keith, Johnathan D, Henderson, Alexander G, Fernandez-Petty, Courtney M, Davis, Joy M, Oden, Ashley M, Birket, Susan E

“…Cystic fibrosis (CF) airway disease is characterized by excessive and accumulative mucus in the airways. Mucociliary clearance becomes defective as mucus…”
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Ivacaftor partially corrects airway inflammation in a humanized G551D rat by Green, Morgan, Lindgren, Natalie, Henderson, Alexander, Keith, Johnathan D, Oden, Ashley M, Birket, Susan E

“…Animal models have been highly informative for understanding the pathogenesis and progression of cystic fibrosis (CF) lung disease. In particular, the CF rat…”
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Acute Infection with a Tobramycin-Induced Small Colony Variant of Staphylococcus aureus Causes Increased Inflammation in the Cystic Fibrosis Rat Lung by Bollar, Gretchen E, Keith, Johnathan D, Oden, Ashley M, Kiedrowski, Megan R, Birket, Susan E

“…Cystic fibrosis (CF) disease is characterized by lifelong infections with pathogens such as Staphylococcus aureus, leading to eventual respiratory failure…”
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Chronic Coinfection with Pseudomonas aeruginosa and Normal Colony Staphylococcus aureus Causes Lung Structural Damage in the Cystic Fibrosis Rat by Bollar, Gretchen E., Keith, Johnathan D., Stanford, Denise D., Oden, Ashley M., Raju, S. Vamsee, Poore, T. Spencer, Birket, Susan E.

“…Cystic fibrosis (CF) respiratory outcomes are heavily influenced by complications of infection. Pseudomonas aeruginosa and Staphylococcus aureus are the most…”
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Static mucus impairs bacterial clearance and allows chronic infection with Pseudomonas aeruginosa in the cystic fibrosis rat by Henderson, Alexander G, Davis, Joy M, Keith, Johnathan D, Green, Morgan E, Oden, Ashley M, Rowe, Steven M, Birket, Susan E

“…Cystic fibrosis (CF) airway disease is characterised by chronic infection. Successful eradication strategies have been hampered by a poor understanding of the…”
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Repurposing sunscreen as an antibiotic: zinc-activated avobenzone inhibits methicillin-resistant Staphylococcus aureus by Andrews, Rachel M, Bollar, Gretchen E, Giattina, A Sophia, Dalecki, Alex G, Wallace Jr, John R, Frantz, Leah, Eschliman, Kayla, Covarrubias-Zambrano, Obdulia, Keith, Johnathan D, Duverger, Alexandra, Wagner, Frederic, Wolschendorf, Frank, Bossmann, Stefan H, Birket, Susan E, Kutsch, Olaf

“…Abstract Methicillin-resistant Staphylococcus aureus (MRSA) is a major healthcare concern with associated healthcare costs reaching over ${\$}$1 billion in a…”
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The Potential of Cr3 [Triaqua-μ3-Oxo-Hexa-μ-Propionatotrichromium(III) Chloride] to Reduce Birth Defects in the Offspring of Diabetic CD-1 Mice by Keith, Johnathan D., Vincent, Christina, Goetsch, Michael, Lemley, Amie, Kraus, Riley, Broussard, Austin, Kildow, Ashley, Faught, Josh, Vincent, John B., Rasco, Jane F.

“…Diabetes mellitus is a growing concern worldwide and leads to multiple complications during pregnancy. Pharmacologic doses of chromium (Cr) have been linked…”
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Chronic co-infection with Pseudomonas aeruginosa and normal colony Staphylococcus aureus causes lung structural damage in the cystic fibrosis rat by Bollar, Gretchen E, Keith, Johnathan D, Stanford, Denise D, Oden, Ashley M, Raju, S Vamsee, Poore, T Spencer, Birket, Susan E

“…Cystic fibrosis (CF) respiratory outcomes are heavily influenced by complications of infection. Pseudomonas aeruginosa and Staphylococcus aureus are the most…”
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