Search Results - "Keith, Gérard"

A new yeast poly(A) polymerase complex involved in RNA quality control by Vanácová, Stepánka, Wolf, Jeannette, Martin, Georges, Blank, Diana, Dettwiler, Sabine, Friedlein, Arno, Langen, Hanno, Keith, Gérard, Keller, Walter

“…Eukaryotic cells contain several unconventional poly(A) polymerases in addition to the canonical enzymes responsible for the synthesis of poly(A) tails of…”
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Microarrays as Cancer Keys: An Array of Possibilities by MOHR, Steve, LEIKAUF, George D, KEITH, Gérard, RIHN, Bertrand H

“…Malignant transformation results from accumulation of genetic and epigenetic events. Functional studies of cancer will be crucial to our understanding of its…”
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A minimalist glutamyl‐tRNA synthetase dedicated to aminoacylation of the tRNAAsp QUC anticodon by Blaise, Mickaël, Becker, Hubert Dominique, Keith, Gérard, Cambillau, Christian, Lapointe, Jacques, Giegé, Richard, Kern, Daniel

“…Escherichia coli encodes YadB, a protein displaying 34% identity with the catalytic core of glutamyl‐tRNA synthetase but lacking the anticodon‐binding domain…”
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Detection of enzymatic activity of transfer RNA modification enzymes using radiolabeled tRNA substrates by Grosjean, Henri, Droogmans, Louis, Roovers, Martine, Keith, Gérard

“…The presence of modified ribonucleotides derived from adenosine, guanosine, cytidine, and uridine is a hallmark of almost all cellular RNA, and especially…”
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Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity by Gehrig, Stefanie, Eberle, Mariel-Esther, Botschen, Flavia, Rimbach, Katharina, Eberle, Florian, Eigenbrod, Tatjana, Kaiser, Steffen, Holmes, Walter M, Erdmann, Volker A, Sprinzl, Mathias, Bec, Guillaume, Keith, Gérard, Dalpke, Alexander H, Helm, Mark

“…Naturally occurring nucleotide modifications within RNA have been proposed to be structural determinants for innate immune recognition. We tested this…”
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Asymptomatic Construct Failure after Metastatic Spine Tumor Surgery: A New Entity or a Continuum with Symptomatic Failure? by Kumar, Naresh, Patel, Ravish, Tan, Barry Wei Loong, Tan, Jiong Hao, Pandita, Naveen, Sonawane, Dhiraj, Lopez, Keith Gerard, Wai, Khin Lay, Hey, Hwee Weng Dennis, Kumar, Aravind, Liu, Gabriel

“…Study Design: Retrospective cohort study.Purpose: To study the incidence, onset, underlying mechanism, clinical course, and factors leading to asymptomatic…”
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Lack of genotoxicity of bitumen fumes in transgenic mouse lung by Micillino, Jean Claude, Coulais, Catherine, Binet, Stéphane, Bottin, Marie-Claire, Keith, Gérard, Moulin, David, Rihn, Bertrand Henri

“…During hot application of bitumen containing materials, e.g. in hot paving or roofing, fumes are emitted that contain polycyclic aromatic compounds. Previous…”
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In the Extraordinary Times of Coronavirus Disease 2019: Clinical Strategies for Performing Spinal Surgery by Barry, Tan Wei Loong, Jeanette, Tan Sze Lyn Jasmin, Ashokka, Balakrishnan, Lopez, Keith Gerard, Thambiah, Joseph, Kumar, Naresh

“…The coronavirus disease 2019 (COVID-19) pandemic has caused pronounced strain on global healthcare systems, forcing the streamlining of clinical activities and…”
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Additives for the crystallization of proteins and nucleic acids by Sauter, Claude, Ng, Joseph D, Lorber, Bernard, Keith, Gérard, Philippe Brion, Wais Hosseini, Mir, Lehn, Jean-Marie, Giegé, Richard

“…Numerous molecules have been described in literature as additives that were indispensable either for nucleation or growth of macromolecular crystals. In some…”
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Thermo-Responsive Hydrogel-Based Soft Valves with Annular Actuation Calibration and Circumferential Gripping by Sivaperuman Kalairaj, Manivannan, Banerjee, Hritwick, Senthil Kumar, Kirthika, Lopez, Keith Gerard, Ren, Hongliang

“…Valves are largely useful for treatment assistance devices, e.g., supporting fluid circulation movement in the human body. However, the valves presently used…”
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Minimally invasive surgery for spinal metastases: Principles, techniques, and outcomes by Naresh Kumar, Andrew Cherian Thomas, Sean Junn Kit Lee, Keith Gerard Lopez, Sarah Shuyun Tang, James Thomas Patrick Decourcy Hallinan

“…The incidence of metastatic spine disease (MSD) is on the rise and is currently present in 70% of patients presenting with systemic cancer. The majority of…”
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An Aminoacyl-tRNA Synthetase-Like Protein Encoded by the Escherichia coli yadB Gene Glutamylates Specifically tRNAAsp by Dubois, Daniel Y., Blaise, Mickaël, Becker, Hubert D., Campanacci, Valérie, Keith, Gérard, Giegé, Richard, Cambillau, Christian, Lapointe, Jacques, Kern, Daniel, Söll, Dieter

“…The product of the Escherichia coli yadB gene is homologous to the N-terminal part of bacterial glutamyl-tRNA synthetases (GluRSs), including the Rossmann fold…”
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Urban Sprawl and Land Value in Batangas City, Philippines by Daguio, Keith Gerard L., Rivera, Ryan Randle B., Reyes, Mario R. Delos, Santiago, Joy T., Mendoza, Jerico E.

“…This article, using a combination of quantitative and qualitative approaches, illustrates that Batangas City for the period 1990–2015 was leaning towards a…”
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City Profile: Batangas City, Philippines by Reyes, Mario R. Delos, Daguio, Keith Gerard L., Gamboa, Mark Anthony M.

“…Cities have always been the predominant centres of political power, economic growth, educational and cultural advancement and technological innovation…”
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Completion of the rabies virus genome sequence determination: highly conserved domains among the L (polymerase) proteins of unsegmented negative-strand RNA viruses by Tordo, N, Poch, O, Ermine, A, Keith, G, Rougeon, F

“…We have now completed the rabies genome structure by the cloning and the sequencing of the entire L gene and the 5' untranscribed region. The L gene encodes a…”
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PARP-1 activity in normal and cancerous human endometrium and its relationship with quantity of abasic sites (AP) by Postawski, Krzysztof, Monist, Marta, Keith, Gérard

“…Poly (ADP-ribose) polymerase (PARP-1) is involved in the processes of DNA repair contributing to the maintenance of genomic stability. Recent data suggest that…”
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An Efficient Mammalian Transfer RNA Target for Bleomycin by Tao, Zhi-Fu, Konishi, Kazuhide, Keith, Gérard, Hecht, Sidney M

“…The antitumor antibiotic bleomycin has long been believed to exert its therapeutic effects at the level of DNA cleavage. Recently, evidence has been presented…”
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Detection and quantification of modified nucleotides in RNA using thin-layer chromatography by Grosjean, Henri, Keith, Gérard, Droogmans, Louis

“…Identification of a modified nucleotide and its localization within an RNA molecule is a difficult task. Only direct sequencing of purified RNA molecules and…”
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Role of Post-transcriptional Modifications of Primer tRNALys,3 in the Fidelity and Efficacy of Plus Strand DNA Transfer during HIV-1 Reverse Transcription by Auxilien, S, Keith, G, Le Grice, S F, Darlix, J L

“…During HIV reverse transcription, (+) strand DNA synthesis is primed by an RNase H-resistant sequence, the polypurine tract, and continues as far as a 18-nt…”
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Presence and coding properties of 2′‐O‐methyl‐5‐carbamoylmethyluridine (ncm5Um) in the wobble position of the anticodon of tRNALeu (UAA) from brewer's yeast by Glasser, Anne-Lise, El Adlouni, Chakib, Keith, Gérard, Sochacka, Elzbieta, Malkiewicz, Andrzej, Santos, Manuel, Tuite, Mick F., Desgrès, Jean

“…The unknown modified nucleoside U* has been isolated by enzymatic and HPLC protocols from tRNALeu(U*AA) recently discovered in brewer's yeast. The pure U*…”
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