Search Results - "Keindl, Magdalena"

Impaired activation of STAT5 upon IL-2 stimulation in Tregs and elevated sIL-2R in Sjögren's syndrome by Keindl, Magdalena, Davies, Richard, Bergum, Brith, Brun, Johan G, Hammenfors, Daniel, Jonsson, Roland, Lyssenko, Valeriya, Appel, Silke

“…Interleukin-2 (IL-2) and the high-affinity IL-2 receptor (IL-2R) are essential for the survival of regulatory T cells (Tregs) which are the main players in…”
Get full text

Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation by Johansson, Bente Berg, Fjeld, Karianne, Solheim, Marie Holm, Shirakawa, Jun, Zhang, Enming, Keindl, Magdalena, Hu, Jiang, Lindqvist, Andreas, Døskeland, Anne, Mellgren, Gunnar, Flatmark, Torgeir, Njølstad, Pål Rasmus, Kulkarni, Rohit N., Wierup, Nils, Aukrust, Ingvild, Bjørkhaug, Lise

“…The localization of glucokinase in pancreatic beta-cell nuclei is a controversial issue. Although previous reports suggest such a localization, the mechanism…”
Get full text

Increased Plasma Soluble Interleukin-2 Receptor Alpha Levels in Patients With Long-Term Type 1 Diabetes With Vascular Complications Associated With IL2RA and PTPN2 Gene Polymorphisms by Keindl, Magdalena, Fedotkina, Olena, du Plessis, Elsa, Jain, Ruchi, Bergum, Brith, Mygind Jensen, Troels, Laustrup Møller, Cathrine, Falhammar, Henrik, Nyström, Thomas, Catrina, Sergiu-Bogdan, Jörneskog, Gun, Groop, Leif, Eliasson, Mats, Eliasson, Björn, Brismar, Kerstin, Nilsson, Peter M, Berg, Tore Julsrud, Appel, Silke, Lyssenko, Valeriya

“…Type 1 diabetes (T1D) is largely considered an autoimmune disease leading to the destruction of insulin-producing pancreatic β cells. Further, patients with…”
Get full text

Serum Myostatin is Upregulated in Obesity and Correlates with Insulin Resistance in Humans by Amor, Melina, Itariu, Bianca K, Moreno-Viedma, Veronica, Keindl, Magdalena, Jürets, Alexander, Prager, Gerhard, Langer, Felix, Grablowitz, Viktor, Zeyda, Maximilian, Stulnig, Thomas M

“…Obesity and type 2 diabetes mellitus have reached an epidemic level, thus novel treatment concepts need to be identified. Myostatin, a myokine known for…”
Get more information

Multidomain Lifestyle Interventions for the Prevention of Cognitive Decline After Ischemic Stroke: Randomized Trial by Matz, Karl, Teuschl, Yvonne, Firlinger, Bernadette, Dachenhausen, Alexandra, Keindl, Magdalena, Seyfang, Leonhard, Tuomilehto, Jaakko, Brainin, Michael

“…BACKGROUND AND PURPOSE—Cognitive impairment occurs in ≤30% of all stroke survivors. However, effective therapies aimed at preventing poststroke cognitive…”
Get full text

Upregulated TNF Expression 1 Year After Bariatric Surgery Reflects a Cachexia-Like State in Subcutaneous Adipose Tissue by Jürets, Alexander, Itariu, Bianca Karla, Keindl, Magdalena, Prager, Gerhard, Langer, Felix, Grablowitz, Viktor, Zeyda, Maximilian, Stulnig, Thomas Michael

“…Background Adipose tissue dysfunction contributes to obesity-associated chronic diseases. In the first year after bariatric surgery, obese patients…”
Get full text

The E3 SUMO ligase PIASγ is a novel interaction partner regulating the activity of diabetes associated hepatocyte nuclear factor-1α by Kaci, Alba, Keindl, Magdalena, Solheim, Marie H., Njølstad, Pål R., Bjørkhaug, Lise, Aukrust, Ingvild

“…The transcription factor hepatocyte nuclear factor-1α (HNF-1A) is involved in normal pancreas development and function. Rare variants in the HNF1A gene can…”
Get full text

Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes by Jain, Ruchi, Özgümüş, Türküler, Jensen, Troels Mygind, du Plessis, Elsa, Keindl, Magdalena, Møller, Cathrine Laustrup, Falhammar, Henrik, Nyström, Thomas, Catrina, Sergiu-Bogdan, Jörneskog, Gun, Jessen, Leon Eyrich, Forsblom, Carol, Haukka, Jani K., Groop, Per-Henrik, Rossing, Peter, Groop, Leif, Eliasson, Mats, Eliasson, Björn, Brismar, Kerstin, Al-Majdoub, Mahmoud, Nilsson, Peter M., Taskinen, Marja-Riitta, Ferrannini, Ele, Spégel, Peter, Berg, Tore Julsrud, Lyssenko, Valeriya

“…Identification of biomarkers associated with protection from developing diabetic complications is a prerequisite for an effective prevention and treatment. The…”
Get full text