Search Results - "Keily, John F"

Total Syntheses of (−) Epilupinine and (−)-Tashiromine Using Imino-Aldol Reactions by Cutter, Amanda C, Miller, Iain R, Keily, John F, Bellingham, Richard K, Light, Mark E, Brown, Richard C. D

“…Short routes to enantiomerically pure indolizidine and quinolizidine alkaloids have been developed using imino-aldol reactions of enolates derived from phenyl…”
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Arylsulphonyl hydroxamic acids: potent and selective matrix metalloproteinase inhibitors by Baxter, Andrew D, Bhogal, Ranjev, Bird, John, Keily, John F, Manallack, David T, Montana, John G, Owen, David A, Pitt, William R, Watson, Robert J, Wills, Ruth E

“…A series of novel matrix metalloproteinase inhibitors is described in which selectivity between MMP and ‘sheddase’ activity has been achieved and which…”
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OSI-930 : A novel selective inhibitor of kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models by GARTON, Andrew J, CREW, Andrew P. A, BITTNER, Mark A, KEILY, John F, BRINER, Paul, HIDDEN, Chris, SREBERNAK, Mary C, PIRRIT, Carrie, O'CONNOR, Matthew, ANNA CHAN, VULEVIC, Bojana, HENNINGER, Dwight, FRANKLIN, Maryland, HART, Karen, SENNELLO, Regina, LI, An-Hu, TAO ZHANG, RICHARDSON, Frank, EMERSON, David L, CASTELHANO, Arlindo L, ARNOLD, Lee D, GIBSON, Neil W, COOKE, Andrew R, WYNNE, Graham M, CASTALDO, Linda, KAHLER, Jennifer, WINSKI, Shannon L, FRANKS, April, BROWN, Eric N

“…OSI-930 is a novel inhibitor of the receptor tyrosine kinases Kit and kinase insert domain receptor (KDR), which is currently being evaluated in clinical…”
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Asymmetric Permanganate-Promoted Oxidative Cyclization of 1,5-Dienes by Using Chiral Phase-Transfer Catalysis This work was supported by the EPSRC (J.F.K.) and the Royal Society (R.C.D.B.). We thank Dr. Barry Lygo (University of Nottingham) for helpful discussions, and Syngenta and Merck Sharp and Dohme for unrestricted grants by Brown, Richard C. D., Keily, John F.

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Asymmetric Permanganate-Promoted Oxidative Cyclization of 1,5-Dienes by Using Chiral Phase-Transfer Catalysis by Brown, Richard C. D., Keily, John F.

“…Bis zu vier neue Stereozentren werden bei der phasentransferkatalysierten oxidativen Cyclisierung achiraler Diene mit Permanganat mit Kontrolle der relativen…”
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Asymmetric Permanganate-Promoted Oxidative Cyclization of 1,5-Dienes by Using Chiral Phase-Transfer Catalysis by Brown, Richard C. D., Keily, John F.

“…Up to four new stereocenters are created with control of the relative and absolute stereochemistry in a single step in the unusual phase‐transfer‐catalyzed…”
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Asymmetric Permanganate-Promoted Oxidative Cyclization of 1,5-Dienes by Using Chiral Phase-Transfer Catalysis by Brown, Richard C. D., Keily, John F.

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