Search Results - "Keijser, Bart"
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Defining the healthy "core microbiome" of oral microbial communities
Published in BMC microbiology (15-12-2009)“…Most studies examining the commensal human oral microbiome are focused on disease or are limited in methodology. In order to diagnose and treat diseases at an…”
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Early respiratory microbiota composition determines bacterial succession patterns and respiratory health in children
Published in American journal of respiratory and critical care medicine (01-12-2014)“…Many bacterial pathogens causing respiratory infections in children are common residents of the respiratory tract. Insight into bacterial colonization patterns…”
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The Impact of Breastfeeding on Nasopharyngeal Microbial Communities in Infants
Published in American journal of respiratory and critical care medicine (01-08-2014)“…Breastfeeding elicits significant protection against respiratory tract infections in infancy. Modulation of respiratory microbiota might be part of the natural…”
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Exploring the oral microbiota of children at various developmental stages of their dentition in the relation to their oral health
Published in BMC medical genomics (04-03-2011)“…An understanding of the relation of commensal microbiota to health is essential in preventing disease. Here we studied the oral microbial composition of…”
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SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation
Published in Nature communications (19-08-2021)“…Characteristic properties of type III CRISPR-Cas systems include recognition of target RNA and the subsequent induction of a multifaceted immune response. This…”
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The entero-endocrine response following a mixed-meal tolerance test with a non-nutritive pre-load in participants with pre-diabetes and type 2 diabetes: A crossover randomized controlled trial proof of concept study
Published in PloS one (25-08-2023)“…Introduction This crossover randomized controlled trial (RCT) investigated differences in short-term entero-endocrine response to a mixed-meal tolerance test…”
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The relation between oral Candida load and bacterial microbiome profiles in Dutch older adults
Published in PloS one (10-08-2012)“…Currently there are no evidence-based ecological measures for prevention of overgrowth and subsequent infection by fungi in the oral cavity. The aim of this…”
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Deep sequencing analyses of low density microbial communities: working at the boundary of accurate microbiota detection
Published in PloS one (06-03-2012)“…Accurate analyses of microbiota composition of low-density communities (10(3)-10(4) bacteria/sample) can be challenging. Background DNA from chemicals and…”
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Nitrate and the Origin of Saliva Influence Composition and Short Chain Fatty Acid Production of Oral Microcosms
Published in Microbial ecology (01-08-2016)“…Nitrate is emerging as a possible health benefactor. Especially the microbial conversion of nitrate to nitrite in the oral cavity and the subsequent conversion…”
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Association of oral health with body weight: a prospective study in community-dwelling older adults
Published in European journal of clinical nutrition (01-06-2020)“…Background To prevent involuntary weight loss in older people, the knowledge about factors affecting body weight (BW) is essential. Therefore, we aimed to…”
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Loss of Microbial Topography between Oral and Nasopharyngeal Microbiota and Development of Respiratory Infections Early in Life
Published in American journal of respiratory and critical care medicine (15-09-2019)“…The respiratory microbiota is increasingly being appreciated as an important mediator in the susceptibility to childhood respiratory tract infections (RTIs)…”
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Determining the Long-term Effect of Antibiotic Administration on the Human Normal Intestinal Microbiota Using Culture and Pyrosequencing Methods
Published in Clinical infectious diseases (15-05-2015)“…The purpose of the study was to assess the effect of ciprofloxacin (500 mg twice daily for 10 days) or clindamycin (150 mg 4 times daily for 10 days) on the…”
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Poor Taste and Smell Are Associated with Poor Appetite, Macronutrient Intake, and Dietary Quality but Not with Undernutrition in Older Adults
Published in The Journal of nutrition (01-03-2021)“…Age-related declines in taste and smell function are widely assumed to contribute to the decrease in appetite and the development of undernutrition in older…”
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Stability and Resilience of Oral Microcosms Toward Acidification and Candida Outgrowth by Arginine Supplementation
Published in Microbial ecology (01-02-2015)“…Dysbiosis induced by low pH in the oral ecosystem can lead to caries, a prevalent bacterial disease in humans. The amino acid arginine is one of the…”
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Same Exposure but Two Radically Different Responses to Antibiotics: Resilience of the Salivary Microbiome versus Long-Term Microbial Shifts in Feces
Published in mBio (10-11-2015)“…Due to the spread of resistance, antibiotic exposure receives increasing attention. Ecological consequences for the different niches of individual microbiomes…”
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Seven-valent pneumococcal conjugate vaccine and nasopharyngeal microbiota in healthy children
Published in Emerging infectious diseases (01-02-2014)“…Seven-valent pneumococcal conjugate vaccine (PCV-7) is effective against vaccine serotype disease and carriage. Nevertheless, shifts in colonization and…”
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Associations of the oral microbiota and Candida with taste, smell, appetite and undernutrition in older adults
Published in Scientific reports (01-12-2021)“…Poor taste and smell function are widely thought to contribute to the development of poor appetite and undernutrition in older adults. It has been hypothesized…”
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Vitamin D supplementation in chronic obstructive pulmonary disease patients with low serum vitamin D: a randomized controlled trial
Published in The American journal of clinical nutrition (01-08-2022)“…Vitamin D deficiency is frequently found in patients with chronic obstructive pulmonary disease (COPD). Vitamin D has antimicrobial, anti-inflammatory, and…”
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Differential modulation by Akkermansia muciniphila and Faecalibacterium prausnitzii of host peripheral lipid metabolism and histone acetylation in mouse gut organoids
Published in mBio (12-08-2014)“…The gut microbiota is essential for numerous aspects of human health. However, the underlying mechanisms of many host-microbiota interactions remain unclear…”
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Acquiring and maintaining a normal oral microbiome: current perspective
Published in Frontiers in cellular and infection microbiology (2014)“…The oral microbiota survives daily physical and chemical perturbations from the intake of food and personal hygiene measures, resulting in a long-term stable…”
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