Search Results - "Keightley, Lauren J."

Roles of three distinct neurogenic motor patterns during pellet propulsion in guinea‐pig distal colon by Costa, Marcello, Keightley, Lauren J., Wiklendt, Lukasz, Hibberd, Timothy J., Arkwright, John W., Omari, Taher, Wattchow, David A., Zagorodnyuk, Vladimir, Brookes, Simon J. H., Dinning, Phil G., Spencer, Nick J.

“…Key points Enteric neural circuits enable isolated preparations of guinea‐pig distal colon to propel solid and fluid contents by a self‐sustaining…”
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Stimulation of extrinsic sympathetic nerves differentially affects neurogenic motor activity in guinea pig distal colon by Smolilo, David J., Hibberd, Timothy J., Costa, Marcello, Dinning, Phil G., Keightley, Lauren J., De Fontgalland, Dayan, Wattchow, David A., Spencer, Nick J.

“…The speed of pellet propulsion through the isolated guinea pig distal colon in vitro significantly exceeds in vivo measurements, suggesting a role for…”
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Motor patterns in the proximal and distal mouse colon which underlie formation and propulsion of feces by Costa, Marcello, Keightley, Lauren J., Hibberd, Timothy J., Wiklendt, Lukasz, Dinning, Phil G., Brookes, Simon J., Spencer, Nick J.

“…Background In herbivores, the proximal and distal colonic regions feature distinct motor patterns underlying formation and propulsion of fecal pellets,…”
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Novel intrinsic neurogenic and myogenic mechanisms underlying the formation of faecal pellets along the large intestine of guinea‐pigs by Costa, Marcello, Hibberd, Timothy J., Keightley, Lauren J., Wiklendt, Lukasz, Kyloh, Melinda A., Dinning, Phil G., Brookes, Simon J. H., Spencer, Nick J.

“…Soft faecal material is transformed into discrete, pellet‐shaped faeces at the colonic flexure. Here, analysis of water content in natural faecal material…”
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Characterization of alternating neurogenic motor patterns in mouse colon by Costa, Marcello, Keightley, Lauren J., Hibberd, Timothy J., Wiklendt, Lukasz, Smolilo, David J., Dinning, Phil G., Brookes, Simon J., Spencer, Nick J.

“…Background Colonic motor complexes (CMCs) have been widely recorded in the large intestine of vertebrates. We have investigated whether in the smooth muscle, a…”
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Neural motor complexes propagate continuously along the full length of mouse small intestine and colon by Costa, Marcello, Hibberd, Timothy James, Keightley, Lauren J, Wiklendt, Lukasz, Arkwright, John W, Dinning, Philip G, Brookes, Simon J H, Spencer, Nick J

“…Cyclical propagating waves of muscle contraction have been recorded in isolated small intestine or colon, referred to here as motor complexes (MCs). Small…”
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Functional changes in low- and high-threshold afferents in obstruction-induced bladder overactivity by Zagorodnyuk, Vladimir P, Keightley, Lauren J, Brookes, Simon J H, Spencer, Nick J, Costa, Marcello, Nicholas, Sarah J

“…Neural mechanisms of lower urinary tract symptoms in obstruction-induced bladder overactivity remain unclear. We made the first single unit recordings from…”
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Identification of neurogenic intestinal motility patterns in silver perch (Bidyanus bidyanus) that persist over wide temperature ranges by Jones, Bradley S., Keightley, Lauren J., Harris, James O., Wiklendt, Lukasz, Spencer, Nick J., Dinning, Phil G.

“…Background Fish are increasingly being utilized as a model species for genetic manipulation studies related to gastrointestinal (GI) motility. Our aim was to…”
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