Search Results - "Kehui Zhang"
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Three-dimensional phosphorus-doped graphene as an efficient metal-free electrocatalyst for electrochemical sensing
Published in Sensors and actuators. B, Chemical (31-03-2017)“…•3D phosphorus (P)-doped graphene (3D-PG) was synthesized by a facile method.•3D-PG was evaluated as an efficient metal-free electrocatalyst for H2O2…”
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2
Development and Validation of a Prognostic Model based on 11 E3-related Genes for Colon Cancer Patients
Published in Current pharmaceutical design (01-01-2024)“…Colon cancer is a common tumor in the gastrointestinal tract with a poor prognosis. According to research reports, ubiquitin-dependent modification systems…”
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3
A Dual PI3K/HDAC Inhibitor Downregulates Oncogenic Pathways in Hematologic Tumors In Vitro and In Vivo
Published in Frontiers in pharmacology (01-10-2021)“…Purpose: To investigate the efficacy and mechanism of compound 23, a PI3K/HDAC dual-target inhibitor, on hematologic tumor cells in vitro and in vivo. Methods:…”
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4
Design, Synthesis, and Biological Evaluation of a Novel Photocaged PI3K Inhibitor toward Precise Cancer Treatment
Published in Journal of medicinal chemistry (10-06-2021)“…Aberrant activation of the PI3K pathway has been intensively targeted for cancer therapeutics for decades, leading to more than 40 PI3K inhibitors advanced…”
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5
Study on the coupling coordination effect and dynamic relationship between tourism development and the ecological environment: a case study of Hainan Island
Published in Frontiers in ecology and evolution (23-02-2024)“…As a Free Trade Port in China, the protection of ecological environment and high-quality tourism development on Hainan Island have become a national strategy…”
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6
Neural substrates of L2-L1 transfer effects on phonological awareness in young Chinese-English bilingual children
Published in NeuroImage (Orlando, Fla.) (01-05-2024)“…•Examine young bilinguals with distant languages (L1: Chinese and L2: English).•The early literacy transfer between L1 and L2 in an L1-dominant…”
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Identification of Novel Thiazolo[5,4- b ]Pyridine Derivatives as Potent Phosphoinositide 3-Kinase Inhibitors
Published in Molecules (Basel, Switzerland) (12-10-2020)“…A series of novel 2-pyridyl, 4-morpholinyl substituted thiazolo[5,4- ]pyridine analogues have been designed and synthesized in this paper. These thiazolo[5,4-…”
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Integration of Bulk and Single-Cell RNA-Seq Data to Construct a Prognostic Model of Membrane Tension-Related Genes for Colon Cancer
Published in Vaccines (Basel) (01-09-2022)“…Background: The plasma membrane provides a highly dynamic barrier for cancer cells to interact with their surrounding microenvironment. Membrane tension, a…”
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Ginsenosides Regulates Innate Immunity to Affect Immune Microenvironment of AIH Through Hippo-YAP/TAZ Signaling Pathway
Published in Frontiers in immunology (11-02-2022)“…Autoimmune hepatitis (AIH) is characterized by chronic progressive liver inflammatory, but there is still no safe and effective medicine. Therefore,…”
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The Main Controlling Factors of the Cambrian Ultra-Deep Dolomite Reservoir in the Tarim Basin
Published in Minerals (Basel) (01-08-2024)“…The genesis of deep-to-ultra-deep dolomite reservoirs in the Tarim Basin is crucial for exploration and development. The Cambrian subsalt dolomite reservoirs…”
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11
Antibody-Dependent Enhancement: ″Evil″ Antibodies Favorable for Viral Infections
Published in Viruses (01-08-2022)“…The pandemics caused by emerging viruses such as severe acute respiratory syndrome coronavirus 2 result in severe disruptions to public health. Vaccines and…”
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The Main Controlling Factors on the Evolution of the Cambrian Carbonate Platform in the Tarim Basin and Its Implications for the Distribution of Ultra-Deep Dolomite Reservoirs
Published in Minerals (Basel) (01-02-2023)“…Cambrian age strata are the critical development and research stratum series of oil and gas reserves in the Tarim Basin, which contains rich oil and gas…”
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13
Spatiotemporally Orchestrated Interactions between Viral and Cellular Proteins Involved in the Entry of African Swine Fever Virus
Published in Viruses (13-12-2021)“…African swine fever (ASF) is a highly contagious hemorrhagic disease in domestic pigs and wild boars with a mortality of up to 100%. The causative agent,…”
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14
Saikosaponin d Alleviates Liver Fibrosis by Negatively Regulating the ROS/NLRP3 Inflammasome Through Activating the ERβ Pathway
Published in Frontiers in pharmacology (25-05-2022)“…Saikosaponin d (SSd) has a steroidal structure and significant anti-inflammatory effects. The purpose of this study was to explore the mechanism underlying…”
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15
Characterization of Immune-Related Molecular Subtypes and a Prognostic Signature Correlating With the Response to Immunotherapy in Patients With Gastric Cancer
Published in Frontiers in immunology (08-07-2022)“…Gastric cancer (GC) is a disease characterized by high molecular and phenotypic heterogeneity and represents a leading cause of cancer-related death worldwide…”
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16
Qi Lang formula relieves constipation via targeting SCF/c-kit signaling pathway: An integrated study of network pharmacology and experimental validation
Published in Heliyon (15-06-2024)“…Constipation is one of the chronic gastrointestinal functional diseases that affects the quality of life. While Qi Lang Formula (QLF) has demonstrated…”
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The E301R protein of African swine fever virus functions as a sliding clamp involved in viral genome replication
Published in mBio (31-10-2023)“…Sliding clamp is a highly conserved protein in the evolution of prokaryotic and eukaryotic cells. The sliding clamp is required for genomic replication as a…”
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Identification of Hub Genes Associated With the Development of Stomach Adenocarcinoma by Integrated Bioinformatics Analysis
Published in Frontiers in oncology (24-05-2022)“…This study was conducted in order to gain a better understanding of the molecular mechanisms of stomach adenocarcinoma (STAD), which is necessary to predict…”
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Histamine Is Responsible for the Neuropathic Itch Induced by the Pseudorabies Virus Variant in a Mouse Model
Published in Viruses (17-05-2022)“…Pseudorabies virus (PRV) is the causative agent of pseudorabies (PR). It can infect a wide range of mammals. PRV infection can cause severe acute neuropathy…”
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CARE program: NCI and FDA interagency collaborations to support oncology small business entrepreneurs
Published in Clinical and translational science (01-03-2023)“…The National Cancer Institute's Small Business Innovation Research Development Center (NCI SBIR) supports the commercialization of novel cancer‐related…”
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