Search Results - "Kehm, Victoria M."

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  1. 1

    Molecular and Biological Compatibility with Host Alpha-Synuclein Influences Fibril Pathogenicity by Luk, Kelvin C., Covell, Dustin J., Kehm, Victoria M., Zhang, Bin, Song, Insung Y., Byrne, Matthew D., Pitkin, Rose M., Decker, Samantha C., Trojanowski, John Q., Lee, Virginia M.-Y.

    Published in Cell reports (Cambridge) (20-09-2016)
    “…The accumulation and propagation of misfolded α-synuclein (α-Syn) is a central feature of Parkinson’s disease and other synucleinopathies. Molecular…”
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  2. 2

    Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice by Luk, Kelvin C, Kehm, Victoria M, Zhang, Bin, O'Brien, Patrick, Trojanowski, John Q, Lee, Virginia M Y

    Published in The Journal of experimental medicine (07-05-2012)
    “…The accumulation of misfolded proteins is a fundamental pathogenic process in neurodegenerative diseases. However, the factors that trigger aggregation of…”
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  3. 3

    α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies by Lim, Youngshin, Kehm, Victoria M, Lee, Edward B, Soper, James H, Li, Chi, Trojanowski, John Q, Lee, Virginia M-Y

    Published in The Journal of neuroscience (06-07-2011)
    “…Abnormally accumulated α-synuclein (α-syn) is a pathological hallmark of Lewy body-related disorders such as Parkinson's disease (PD) and dementia with Lewy…”
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    Journal Article