Search Results - "Kefas, BA"

AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase by Kefas, BA, Cai, Y, Ling, Z, Heimberg, H, Hue, L, Pipeleers, D, Van de Casteele, M

“…We have recently shown that conditions known to activate AMP-activated protein kinase (AMPK) in primary beta-cells can trigger their apoptosis. The present…”
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Metformin-induced stimulation of AMP-activated protein kinase in β-cells impairs their glucose responsiveness and can lead to apoptosis by Kefas, Benjamin A., Cai, Ying, Kerckhofs, Karen, Ling, Zhidong, Martens, Geert, Heimberg, Harry, Pipeleers, Daniël, Casteele, Mark Van de

“…Metformin is an anti-diabetic drug that increases glucose utilization in insulin-sensitive tissues. The effect is in part attributable to a stimulation of…”
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Sustained activation of AMP-activated protein kinase induces c-Jun N-terminal kinase activation and apoptosis in liver cells by Meisse, Delphine, Van de Casteele, Mark, Beauloye, Christophe, Hainault, Isabelle, Kefas, Benjamin A, Rider, Mark H, Foufelle, Fabienne, Hue, Louis

“…The aim of this work was to study the effect of a sustained activation of AMP-activated protein kinase (AMPK) on liver cell survival. AMPK activation was…”
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AICA-riboside induces apoptosis of pancreatic beta cells through stimulation of AMP-activated protein kinase by KEFAS, B. A, HEIMBERG, H, VAULONT, S, MEISSE, D, HUE, L, PIPELEERS, D, CASTEELE, M

“…Prolonged exposure of beta cells to low glucose concentrations triggers their apoptosis and is known to activate AMP-activated protein kinase (AMPK) in beta…”
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Prolonged culture in low glucose induces apoptosis of rat pancreatic β-cells through induction of c-myc by Van de Casteele, Mark, Kefas, Benjamin Ate, Cai, Ying, Heimberg, Harry, Scott, Donald K, Henquin, Jean-Claude, Pipeleers, Daniël, Jonas, Jean-Christophe

“…Prolonged culture in low-glucose concentrations (⩽5 mM) induces apoptosis in pancreatic β-cells by a poorly defined mechanism. We now show that, in both…”
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