Search Results - "Keersmaecker, Sigrid C.J. De"
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Isolation of Drug-Resistant Gallibacterium anatis from Calves with Unresponsive Bronchopneumonia, Belgium
Published in Emerging infectious diseases (01-04-2020)“…Gallibacterium anatis is an opportunistic pathogen, previously associated with deaths in poultry, domestic birds, and occasionally humans. We obtained G…”
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community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2
Published in BMC systems biology (18-01-2011)“…Background: Metabolic reconstructions (MRs) are common denominators in systems biology and represent biochemical, genetic, and genomic (BiGG) knowledge-bases…”
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Salmonella biofilms: An overview on occurrence, structure, regulation and eradication
Published in Food research international (01-03-2012)“…The ability of Salmonella to form complex surface-associated communities, called biofilms, contributes to its resistance and persistence in both host and…”
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Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens
Published in Nature reviews. Microbiology (01-03-2010)“…Key Points The interaction of probiotic surface molecules with host pattern recognition receptors (PRRs) and associated co-receptors plays a key part in the…”
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Combining short and long read sequencing to characterize antimicrobial resistance genes on plasmids applied to an unauthorized genetically modified Bacillus
Published in Scientific reports (09-03-2020)“…Antimicrobial resistance (AMR) is a major public health threat. Plasmids are able to transfer AMR genes among bacterial isolates. Whole genome sequencing (WGS)…”
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Impact of DNA extraction on whole genome sequencing analysis for characterization and relatedness of Shiga toxin-producing Escherichia coli isolates
Published in Scientific reports (04-09-2020)“…Whole genome sequencing (WGS) has proven to be the ultimate tool for bacterial isolate characterization and relatedness determination. However, standardized…”
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Detection and discrimination of five E. coli pathotypes using a combinatory SYBR® Green qPCR screening system
Published in Applied microbiology and biotechnology (01-04-2018)“…A detection and discrimination system for five Escherichia coli pathotypes, based on a combination of 13 SYBR® Green qPCR, has been developed, i.e.,…”
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Concise and Diversity-Oriented Route toward Polysubstituted 2-Aminoimidazole Alkaloids and Their Analogues
Published in Angewandte Chemie (International ed.) (03-12-2010)“…Alkaloids of the naamine family were synthesized from diverse propargylamines in just two steps (see scheme: R1=Me, R2=substituted benzyl, R3=Ar). Thus, the…”
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Identification of a Gene Cluster for the Biosynthesis of a Long, Galactose-Rich Exopolysaccharide in Lactobacillus rhamnosus GG and Functional Analysis of the Priming Glycosyltransferase
Published in Applied and Environmental Microbiology (01-06-2009)“…Cell surface polysaccharides have an established role as virulence factors in human bacterial pathogens. Less documented are the biosynthesis and biological…”
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Identification of an unauthorized genetically modified bacteria in food enzyme through whole-genome sequencing
Published in Scientific reports (27-04-2020)“…Recently, the unexpected presence of a viable unauthorized genetically modified bacterium in a commercialized food enzyme (protease) product originating from a…”
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Development of a real-time PCR method for the genoserotyping of Salmonella Paratyphi B variant Java
Published in Applied microbiology and biotechnology (01-06-2019)“…Discriminating between d -tartrate fermenting and non-fermenting strains of Salmonella enterica subsp. enterica serotype Paratyphi B is of major importance as…”
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Nanopore sequencing technology: a new route for the fast detection of unauthorized GMO
Published in Scientific reports (21-05-2018)“…In order to strengthen the current genetically modified organism (GMO) detection system for unauthorized GMO, we have recently developed a new workflow based…”
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Impact of Environmental and Genetic Factors on Biofilm Formation by the Probiotic Strain Lactobacillus rhamnosus GG
Published in Applied and Environmental Microbiology (01-11-2007)“…Lactobacillus rhamnosus GG (ATCC 53103) is one of the clinically best-studied probiotic organisms. Moreover, L. rhamnosus GG displays very good in vitro…”
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Brominated Furanones Inhibit Biofilm Formation by Salmonella enterica Serovar Typhimurium
Published in Applied and Environmental Microbiology (01-11-2008)“…Salmonella enterica serovar Typhimurium is a main cause of bacterial food-borne diseases. As Salmonella can form biofilms in which it is better protected…”
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Adherence factors of Lactobacillus in the human gastrointestinal tract
Published in FEMS microbiology letters (01-11-2007)“…Despite the increasing number of scientific reports describing adhesion of Lactobacillus to components of the human intestinal mucosa, information on the…”
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NGS for (Hemato-) Oncology in Belgium: Evaluation of Laboratory Performance and Feasibility of a National External Quality Assessment Program
Published in Cancers (01-11-2020)“…Next-generation sequencing (NGS) is being integrated into routine clinical practice in the field of (hemato-) oncology to search for variants with diagnostic,…”
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Detection and identification of authorized and unauthorized GMOs using high-throughput sequencing with the support of a sequence-based GMO database
Published in Food chemistry. Molecular sciences (30-07-2022)“…•Sequence-based database Nexplorer describing EU-authorized GMOs was developed.•Sequences were annotated and presented in structured and extractable…”
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The Benefits of Whole Genome Sequencing for Foodborne Outbreak Investigation from the Perspective of a National Reference Laboratory in a Smaller Country
Published in Foods (01-08-2020)“…Gradually, conventional methods for foodborne pathogen typing are replaced by whole genome sequencing (WGS). Despite studies describing the overall benefits,…”
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multiplex oligonucleotide ligation-PCR as a complementary tool for subtyping of Salmonella Typhimurium
Published in Applied microbiology and biotechnology (01-10-2015)“…Subtyping below the serovar level is essential for surveillance and outbreak detection and investigation of Salmonella enterica subsp. enterica serovar…”
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A shotgun metagenomics approach to detect and characterize unauthorized genetically modified microorganisms in microbial fermentation products
Published in Food chemistry. Molecular sciences (30-07-2021)“…•The presence of GMM or its DNA in microbial fermentation products prohibited by EU.•The lack of appropriate detection tools challenges targeting unknown…”
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