Search Results - "Keers, Robert"

Gene-environment interaction and psychiatric disorders: Review and future directions by Assary, Elham, Vincent, John Paul, Keers, Robert, Pluess, Michael

“…Empirical studies suggest that psychiatric disorders result from a complex interplay between genetic and environmental factors. Most evidence for such…”
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Paranoid Ideation and Violence: Meta-analysis of Individual Subject Data of 7 Population Surveys by Coid, Jeremy W, Ullrich, Simone, Bebbington, Paul, Fazel, Seena, Keers, Robert

“…There is controversy whether associations between psychosis and violence are due to coexisting substance misuse and factors increasing risk in nonpsychotic…”
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Genome-wide stress sensitivity moderates the stress-depression relationship in a nationally representative sample of adults by Davidson, Trent, Braudt, David B., Keers, Robert, Assary, Elham, Harris, Kathleen Mullan, Boardman, Jason D.

“…We re-evaluate the findings of one of the most cited and disputed papers in gene-environment interaction (GxE) literature. In 2003, a paper was published in…”
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Clinical Predictors of Response to Cognitive-Behavioral Therapy in Pediatric Anxiety Disorders: The Genes for Treatment (GxT) Study by Hudson, Jennifer L., PhD, Keers, Robert, PhD, Roberts, Susanna, MSc, Coleman, Jonathan R.I., MSc, Breen, Gerome, PhD, Arendt, Kristian, PhD, Bögels, Susan, PhD, Cooper, Peter, DPhil, Creswell, Cathy, DClinPsy, PhD, Hartman, Catharina, PhD, Heiervang, Einar R., MD, PhD, Hötzel, Katrin, PhD, In-Albon, Tina, PhD, Lavallee, Kristen, PhD, Lyneham, Heidi J., PhD, Marin, Carla E., PhD, McKinnon, Anna, PhD, Meiser-Stedman, Richard, PhD, Morris, Talia, BPsych (Hons), Nauta, Maaike, PhD, Rapee, Ronald M., PhD, Schneider, Silvia, PhD, Schneider, Sophie C., BPsych(Hons), Silverman, Wendy K., PhD, Thastum, Mikael, PhD, Thirlwall, Kerstin, DClinPsy, Waite, Polly, DClinPsy, Wergeland, Gro Janne, MD, Lester, Kathryn J., DPhil, Eley, Thalia C., PhD

“…Objective The Genes for Treatment study is an international, multisite collaboration exploring the role of genetic, demographic, and clinical predictors in…”
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A Genome-Wide Test of the Differential Susceptibility Hypothesis Reveals a Genetic Predictor of Differential Response to Psychological Treatments for Child Anxiety Disorders by Keers, Robert, Coleman, Jonathan R I, Lester, Kathryn J, Roberts, Susanna, Breen, Gerome, Thastum, Mikael, Bögels, Susan, Schneider, Silvia, Heiervang, Einar, Meiser-Stedman, Richard, Nauta, Maaike, Creswell, Cathy, Thirlwall, Kerstin, Rapee, Ronald M, Hudson, Jennifer L, Lewis, Cathryn, Plomin, Robert, Eley, Thalia C

“…The differential susceptibly hypothesis suggests that certain genetic variants moderate the effects of both negative and positive environments on mental health…”
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Polygenic risk scores for schizophrenia and major depression are associated with socio-economic indicators of adversity in two British community samples by Machlitt-Northen, Sandra, Keers, Robert, Munroe, Patricia B., Howard, David M., Pluess, Michael

“…Schizophrenia (SCZ) and major depressive disorder (MDD) are complex psychiatric disorders which contribute substantially to the global burden of disease. Both…”
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HPA AXIS RELATED GENES AND RESPONSE TO PSYCHOLOGICAL THERAPIES: GENETICS AND EPIGENETICS by Roberts, Susanna, Keers, Robert, Lester, Kathryn J, Coleman, Jonathan R. I., Breen, Gerome, Arendt, Kristian, Blatter-Meunier, Judith, Cooper, Peter, Creswell, Cathy, Fjermestad, Krister, Havik, Odd E., Herren, Chantal, Hogendoorn, Sanne M., Hudson, Jennifer L., Krause, Karen, Lyneham, Heidi J., Morris, Talia, Nauta, Maaike, Rapee, Ronald M., Rey, Yasmin, Schneider, Silvia, Schneider, Sophie C., Silverman, Wendy K., Thastum, Mikael, Thirlwall, Kerstin, Waite, Polly, Eley, Thalia C., Wong, Chloe C. Y.

“…Background Hypothalamic–pituitary–adrenal (HPA) axis functioning has been implicated in the development of stress‐related psychiatric diagnoses and response to…”
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The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder by Malki, Karim, Keers, Robert, Tosto, Maria Grazia, Lourdusamy, Anbarasu, Carboni, Lucia, Domenici, Enrico, Uher, Rudolf, McGuffin, Peter, Schalkwyk, Leonard C

“…Traditional diagnoses of major depressive disorder (MDD) suggested that the presence or absence of stress prior to onset results in either 'reactive' or…”
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Reduced anxiety and depression-like behaviours in the circadian period mutant mouse afterhours by Keers, Robert, Pedroso, Inti, Breen, Gerome, Aitchison, Kathy J, Nolan, Patrick M, Cichon, Sven, Nöthen, Markus M, Rietschel, Marcella, Schalkwyk, Leonard C, Fernandes, Cathy

“…Disruption of the circadian rhythm is a key feature of bipolar disorder. Variation in genes encoding components of the molecular circadian clock has been…”
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The CogBIAS longitudinal study protocol: cognitive and genetic factors influencing psychological functioning in adolescence by Booth, Charlotte, Songco, Annabel, Parsons, Sam, Heathcote, Lauren, Vincent, John, Keers, Robert, Fox, Elaine

“…Optimal psychological development is dependent upon a complex interplay between individual and situational factors. Investigating the development of these…”
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Dissecting the Genetic Heterogeneity of Depression Through Age at Onset by Power, Robert A., Keers, Robert, Ng, Mandy Y., Butler, Amy W., Uher, Rudolf, Cohen-Woods, Sarah, Ising, Marcus, Craddock, Nick, Owen, Michael J., Korszun, Ania, Jones, Lisa, Jones, Ian, Gill, Michael, Rice, John P., Hauser, Joanna, Henigsberg, Neven, Maier, Wolfgang, Zobel, Astrid, Mors, Ole, Placentino, Anna S., Rietschel, Marcella, Souery, Daniel, Kozel, Dejan, Preisig, Martin, Lucae, Susanne, Binder, Elisabeth B., Aitchison, Katherine J., Tozzi, Federica, Muglia, Pierandrea, Breen, Gerome, Craig, Ian W., Farmer, Anne E., Müller-Myhsok, Bertram, McGuffin, Peter, Lewis, Cathryn M.

“…Genome‐wide studies in major depression have identified few replicated associations, potentially due to heterogeneity within the disorder. Several studies have…”
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Childhood quality influences genetic sensitivity to environmental influences across adulthood: A life-course Gene × Environment interaction study by Keers, Robert, Pluess, Michael

“…While environmental adversity has been shown to increase risk for psychopathology, individuals differ in their sensitivity to these effects. Both genes and…”
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Response to Pinta by Keers, Robert

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Delusions, Anger, and Serious Violence: New Findings From the MacArthur Violence Risk Assessment Study by ULLRICH, Simone, KEERS, Robert, COID, Jeremy W

“…Recent research on the association between delusions and violence has suggested complex and differing pathways. Furthermore, it has been emphasized that…”
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Association of Violence With Emergence of Persecutory Delusions in Untreated Schizophrenia by Keers, Robert, Ullrich, Simone, DeStavola, Bianca L, Coid, Jeremy W

“…Persecutory delusions can emerge in prisoners with untreated schizophrenia, leading to violent behavior, but maintaining psychiatric treatment after release…”
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The relationship between delusions and violence: findings from the East London first episode psychosis study by Coid, Jeremy W, Ullrich, Simone, Kallis, Constantinos, Keers, Robert, Barker, Dave, Cowden, Fiona, Stamps, Rebekah

“…Psychotic persons who are violent often explain their violence as being due to delusions. However, research has failed to confirm associations between…”
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Genetic architecture of Environmental Sensitivity reflects multiple heritable components: a twin study with adolescents by Assary, Elham, Zavos, Helena M. S., Krapohl, Eva, Keers, Robert, Pluess, Michael

“…Humans differ substantially in how strongly they respond to similar experiences. Theory suggests that such individual differences in susceptibility to…”
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Gene–Environment Interaction in Major Depression and Antidepressant Treatment Response by Keers, Robert, Uher, Rudolf

“…Response to antidepressants is interindividually variable. It has been suggested that this variability is a direct consequence of etiological heterogeneity…”
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Gang Membership, Violence, and Psychiatric Morbidity by Coid, Jeremy W., Ullrich, Simone, Keers, Robert, Bebbington, Paul, DeStavola, Bianca L., Kallis, Constantinos, Yang, Min, Reiss, David, Jenkins, Rachel, Donnelly, Peter

“…ObjectiveGang members engage in many high-risk activities associated with psychiatric morbidity, particularly violence-related ones. The authors investigated…”
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Interplay between polygenic risk for mood disorders and stressful life events in bipolar disorder by Hosang, Georgina M., Shakoor, Sania, King, Nicole, Sanches, Marcos, Vincent, John B., Kennedy, James L., McGuffin, Peter, Keers, Robert, Zai, Clement C.

“…Although genetic and environmental factors are involved in the aetiology of bipolar disorder [BD], studies focused on their interplay are lacking. The current…”
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