Search Results - "Keenan, Tiarnan D."

DeepSeeNet: A Deep Learning Model for Automated Classification of Patient-based Age-related Macular Degeneration Severity from Color Fundus Photographs by Peng, Yifan, Dharssi, Shazia, Chen, Qingyu, Keenan, Tiarnan D., Agrón, Elvira, Wong, Wai T., Chew, Emily Y., Lu, Zhiyong

“…In assessing the severity of age-related macular degeneration (AMD), the Age-Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of…”
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Age-Related Macular Degeneration: Epidemiology and Clinical Aspects by Keenan, Tiarnán D L, Cukras, Catherine A, Chew, Emily Y

“…Age-related macular degeneration (AMD) is a degenerative disease of the human retina affecting individuals over the age of 55 years. This heterogeneous…”
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Intravitreal injections: past trends and future projections within a UK tertiary hospital by Chopra, Reena, Preston, Gabriella C., Keenan, Tiarnan D. L., Mulholland, Pádraig, Patel, Praveen J., Balaskas, Konstantinos, Hamilton, Robin D., Keane, Pearse A.

“…Aims To describe past trends and future projections for the number of intravitreal injections being administered at a large tertiary hospital in London, United…”
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Associations between age-related macular degeneration, Alzheimer disease, and dementia: record linkage study of hospital admissions by Keenan, Tiarnan D L, Goldacre, Raph, Goldacre, Michael J

“…The potential association between age-related macular degeneration (AMD) and Alzheimer disease (AD) is uncertain and has implications for understanding disease…”
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Association of 2-Year Progression Along the AREDS AMD Scale and Development of Late Age-Related Macular Degeneration or Loss of Visual Acuity: AREDS Report 41 by Vitale, Susan, Agrón, Elvira, Clemons, Traci E, Keenan, Tiarnan D L, Domalpally, Amitha, Danis, Jr, Ronald P, Chew, Emily Y

“…The Age-Related Eye Disease Study age-related macular degeneration (AREDS AMD) scale is designed to classify AMD severity. The present cohort study explored…”
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Progression of Age-Related Macular Degeneration Among Individuals Homozygous for Risk Alleles on Chromosome 1 (CFH-CFHR5) or Chromosome 10 (ARMS2/HTRA1) or Both by Schmitz-Valckenberg, Steffen, Fleckenstein, Monika, Zouache, Moussa A, Pfau, Maximilian, Pappas, Christian, Hageman, Jill L, Agrón, Elvira, Malley, Claire, Keenan, Tiarnan D L, Chew, Emily Y, Hageman, Gregory S

“…Age-related macular degeneration (AMD) is a common cause of irreversible vision loss among individuals older than 50 years. Although considerable advances have…”
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Longitudinal Study of Dark Adaptation as a Functional Outcome Measure for Age-Related Macular Degeneration by Chen, Katherine G., Alvarez, Jason A., Yazdanie, Mohammad, Papudesu, Chandana, Wong, Wai T., Wiley, Henry E., Keenan, Tiarnan D., Chew, Emily Y., Ferris, Frederick L., Cukras, Catherine A.

“…To investigate the natural history of dark adaptation (DA) function as measured by the change in rod intercept time (RIT) over 4 years and to correlate RIT…”
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Comparison of agents using higher dose anti-VEGF therapy for treatment-resistant neovascular age-related macular degeneration by Broadhead, Geoffrey K., Keenan, Tiarnan D. L., Chew, Emily Y., Wiley, Henry E., Cukras, Catherine A.

“…Purpose To explore the comparative efficacy and safety of higher dose intravitreal bevacizumab, ranibizumab, or aflibercept for treatment-resistant neovascular…”
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Macular Thickness in Intermediate Age-Related Macular Degeneration Is Influenced by Disease Severity and Subretinal Drusenoid Deposit Presence by Chiang, Trent Tsun-Kang, Keenan, Tiarnan D, Agrón, Elvira, Liao, Jennifer, Klein, Brandon, Chew, Emily Y, Cukras, Catherine A, Wong, Wai T

“…To investigate how macular thickness varies with intermediate age-related macular degeneration (iAMD) severity and the presence of subretinal drusenoid…”
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Characterising treatment outcomes of patients achieving quarterly aflibercept dosing for neovascular age-related macular degeneration: real-world clinical outcomes from a large tertiary care centre by Fu, Dun Jack, Hanumunthadu, Daren, Keenan, Tiarnan D. L., Wagner, Siegfried, Balsakas, Konstantinos, Keane, Pearse A., Patel, Praveen J.

“…Background and objective To evaluate the proportion of patients achieving a 12-week (q12) aflibercept dosing interval in patients with neovascular age-related…”
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Structural integrity of retinal pigment epithelial cells in eyes with age-related scattered hypofluorescent spots on late phase indocyanine green angiography (ASHS-LIA) by Li, Joanne, Aguilera, Nancy, Liu, Tao, Bower, Andrew J., Giannini, John P., Cukras, Catherine, Keenan, Tiarnan D. L., Chew, Emily, Brooks, Brian P., Zein, Wadih M., Huryn, Laryssa A., Hufnagel, Robert B., Tam, Johnny

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Association of Dietary Nitrate and a Mediterranean Diet With Age-Related Macular Degeneration Among US Adults: The Age-Related Eye Disease Study (AREDS) and AREDS2 by Broadhead, Geoffrey K, Agrón, Elvira, Peprah, David, Keenan, Tiarnan D L, Lawler, Thomas P, Mares, Julie, Chew, Emily Y

“…Low dietary nitrate intake has previously been suggested to be a risk factor for age-related macular degeneration (AMD) progression; however, this finding has…”
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Predicting risk of late age-related macular degeneration using deep learning by Peng, Yifan, Keenan, Tiarnan D., Chen, Qingyu, Agrón, Elvira, Allot, Alexis, Wong, Wai T., Chew, Emily Y., Lu, Zhiyong

“…By 2040, age-related macular degeneration (AMD) will affect ~288 million people worldwide. Identifying individuals at high risk of progression to late AMD, the…”
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Trends over time and geographical variation in rates of intravitreal injections in England by Keenan, Tiarnan D L, Wotton, Clare J, Goldacre, Michael J

“…The recent emergence of antivascular endothelial growth factor (anti-VEGF) drugs has led to increased numbers of patients undergoing intravitreal injection for…”
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Automated Quantitative Assessment of Retinal Fluid Volumes as Important Biomarkers in Neovascular Age-Related Macular Degeneration by Keenan, Tiarnan D.L., Chakravarthy, Usha, Loewenstein, Anat, Chew, Emily Y., Schmidt-Erfurth, Ursula

“…To evaluate retinal fluid volume data extracted from optical coherence tomography (OCT) scans by artificial intelligence algorithms in the treatment of…”
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A deep network DeepOpacityNet for detection of cataracts from color fundus photographs by Elsawy, Amr, Keenan, Tiarnan D. L., Chen, Qingyu, Thavikulwat, Alisa T., Bhandari, Sanjeeb, Quek, Ten Cheer, Goh, Jocelyn Hui Lin, Tham, Yih-Chung, Cheng, Ching-Yu, Chew, Emily Y., Lu, Zhiyong

“…Background Cataract diagnosis typically requires in-person evaluation by an ophthalmologist. However, color fundus photography (CFP) is widely performed…”
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Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera by Keenan, Tiarnan D L, Clark, Simon J, Unwin, Richard D, Ridge, Liam A, Day, Anthony J, Bishop, Paul N

“…To examine the presence and distribution of proteoglycan (PG) core proteins in the adult human retina, choroid, and sclera. Postmortem human eye tissue was…”
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Risk of selected eye diseases in people admitted to hospital for hypertension or diabetes mellitus: record linkage studies by Goldacre, Michael J, Wotton, Clare J, Keenan, Tiarnan D L

“…Associations among hypertension, diabetes mellitus and some ophthalmic diseases are well established; associations with others are more equivocal. The aim was…”
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Trends in corneal graft surgery in the UK by Keenan, Tiarnan D L, Carley, Fiona, Yeates, David, Jones, Mark N A, Rushton, Sally, Goldacre, Michael J

“…The aims of this study were to examine trends over time and regional variation in rates of corneal graft surgery in the UK. The hospital in-patient enquiry…”
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Mapping the differential distribution of glycosaminoglycans in the adult human retina, choroid, and sclera by Clark, Simon J, Keenan, Tiarnan D L, Fielder, Helen L, Collinson, Lisa J, Holley, Rebecca J, Merry, Catherine L R, van Kuppevelt, Toin H, Day, Anthony J, Bishop, Paul N

“…PURPOSE. To map the distribution of different classes of glycosaminoglycans (GAGs) in the healthy human retina, choroid, and sclera. METHODS. Frozen tissue…”
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