Search Results - "Keenan, Jacqueline"

Colonization with enterotoxigenic Bacteroides fragilis is associated with early-stage colorectal neoplasia by Purcell, Rachel V, Pearson, John, Aitchison, Alan, Dixon, Liane, Frizelle, Frank A, Keenan, Jacqueline I

“…Enterotoxigenic Bacteroides fragilis (ETBF) is a toxin-producing bacteria thought to possibly promote colorectal carcinogenesis by modulating the mucosal…”
Get full text

Detection of Fusobacterium nucleatum DNA in primary care patient stool samples does not predict progression of colorectal neoplasia by Aitchison, Alan, Pearson, John F, Purcell, Rachel V, Frizelle, Frank A, Keenan, Jacqueline I

“…Carriage of certain bacterial species may represent potential biomarkers of colorectal cancer (CRC). Prominent among these is Fusobacterium nucleatum. We…”
Get full text

Uptake of Helicobacter pylori Outer Membrane Vesicles by Gastric Epithelial Cells by Parker, Heather, Chitcholtan, Kenny, Hampton, Mark B, Keenan, Jacqueline I

“…Helicobacter pylori bacteria colonize the human stomach where they stimulate a persistent inflammatory response. H. pylori is considered noninvasive; however,…”
Get full text

Children With Cystic Fibrosis Have Elevated Levels of Fecal Chitinase‐3‐like‐1 by Permain, Jessica, Appleton, Laura, Ho, Shaun S. C., Coffey, Michael, Ooi, Chee Y., Keenan, Jacqueline I., Day, Andrew S.

“…Although chitinase‐3‐like‐1 (CHI3L1), predominately produced by epithelial cells and macrophages, is relevant to pulmonary disease in cystic fibrosis (CF),…”
Get full text

Helicobacter pylori infection perturbs iron homeostasis in gastric epithelial cells by Flores, Sebastian E, Aitchison, Alan, Day, Andrew S, Keenan, Jacqueline I

“…The iron deficiency anaemia that often accompanies infection with Helicobacter pylori may reflect increased uptake of iron into gastric epithelial cells. Here…”
Get full text

Patient perceptions of current and potential inflammatory bowel disease diagnostic and monitoring tests by Ho, Shaun S. C., Keenan, Jacqueline I., Day, Andrew S.

“…Background Less invasive inflammatory bowel disease (IBD) tests are increasingly being incorporated into clinical practice as adjuncts to endoscopy to monitor…”
Get full text

Could Microplastics Be a Driver for Early Onset Colorectal Cancer? by Li, Shelley, Keenan, Jacqueline I, Shaw, Ian C, Frizelle, Frank A

“…The incidence of colorectal cancer in those under 50 years of age (early onset colorectal cancer (EOCRC)) is increasing throughout the world. This has…”
Get full text

Role of serological tests in the diagnosis of coeliac disease in children in New Zealand by Ho, Shaun SC, Keenan, Jacqueline I, Day, Andrew S

“…Aim To circumvent the need for an endoscopic biopsy to establish the diagnosis of coeliac disease (CD), the European Society for Paediatric Gastroenterology,…”
Get full text

Toxigenic gut bacteria, diet and colon carcinogenesis by Keenan, Jacqueline I., Frizelle, Frank A.

“…Colorectal cancer is the second most commonly diagnosed cancer in New Zealand and while the overall incidence of CRC is declining, the changing population…”
Get full text

CDH1 gene mutation in early-onset, colorectal signet-ring cell carcinoma by Aitchison, Alan, Hakkaart, Christopher, Whitehead, Martin, Khan, Sadaf, Siddique, Sabeehuddin, Ahmed, Rashida, Frizelle, Frank A., Keenan, Jacqueline I.

“…Colorectal signet-ring cell carcinomas (SRCC) are highly malignant tumours with poor prognosis that disproportionately affect younger patients. There is…”
Get full text

APC Mutations Are Not Confined to Hotspot Regions in Early-Onset Colorectal Cancer by Aitchison, Alan, Hakkaart, Christopher, Day, Robert C, Morrin, Helen R, Frizelle, Frank A, Keenan, Jacqueline I

“…While overall colorectal cancer (CRC) cases have been declining worldwide there has been an increase in the incidence of the disease among patients under 50…”
Get full text

Composition and function of Helicobacter pylori outer membrane vesicles by Parker, Heather, Keenan, Jacqueline I.

“…The gastric pathogen Helicobacter pylori sheds outer membrane vesicles (OMV) that possess many of the surface elements of the bacterium. Here we review current…”
Get full text

Profile of Helicobacter pylori infections among children in the South Island of New Zealand (2010–2021) by Vernon‐Roberts, Angharad, Premaratne, Malshi, Wright, Raewyn, Keenan, Jacqueline I., Day, Andrew S.

“…Background Helicobacter pylori is a gram‐negative gut bacterium most often acquired during childhood. International guidelines state that children with…”
Get full text

The incidence of early onset colorectal cancer in Aotearoa New Zealand: 2000-2020 by Waddell, Oliver, Pearson, John, McCombie, Andrew, Marshall, Harriet, Purcell, Rachel, Keenan, Jacqueline, Glyn, Tamara, Frizelle, Frank

“…The incidence of early-onset colorectal cancer (EOCRC), diagnosed before age 50, has been rising in many countries in the past few decades. This study aims to…”
Get full text

The Role of Gastrointestinal-Related Fatty Acid-Binding Proteins as Biomarkers in Gastrointestinal Diseases by Ho, Shaun S. C., Keenan, Jacqueline I., Day, Andrew S.

“…The fatty acid-binding proteins play a major role in intracellular transportation of long-chain fatty acids. Nine fatty acid-binding proteins have been…”
Get full text

Comparison of standard, quantitative and digital PCR in the detection of enterotoxigenic Bacteroides fragilis by Purcell, Rachel V., Pearson, John, Frizelle, Frank A., Keenan, Jacqueline I.

“…Gut colonization with enterotoxigenic Bacteroides fragilis (ETBF) appears to be associated with the development of colorectal cancer. However, differences in…”
Get full text

Helicobacter pylori outer membrane vesicles inhibit human T cell responses via induction of monocyte COX-2 expression by Hock, Barry D, McKenzie, Judith L, Keenan, Jacqueline I

“…The modulation of T cell responses by Helicobacter pylori is thought to potentiate both H. pylori persistence and development of gastric pathologies including…”
Get full text

Biomarkers to Detect Early-Stage Colorectal Cancer by Keenan, Jacqueline I, Frizelle, Frank A

“…Colorectal cancer is a leading cause of mortality worldwide. The high incidence and the acceleration of incidence in younger people reinforces the need for…”
Get full text

Concentrations of Fecal Bile Acids in Participants with Functional Gut Disorders and Healthy Controls by James, Shanalee C., Fraser, Karl, Young, Wayne, Heenan, Phoebe E., Gearry, Richard B., Keenan, Jacqueline I., Talley, Nicholas J., Joyce, Susan A., McNabb, Warren C., Roy, Nicole C.

“…Bile acids are metabolites involved in nutrient absorption and signaling with levels influenced by dietary intake, metabolic processes, and the gut microbiome…”
Get full text

Australasian Pediatric Gastroenterologists’ Perspectives and Practices of Celiac Disease Diagnosis and Management by Ho, Shaun S. C., Hall, Sophie, Keenan, Jacqueline I., Day, Andrew S.

“…Background The application of the European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) celiac disease (CeD) guidelines by…”
Get full text