Search Results - "Keeling, Suzanne E"
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Lamprey (Geotria australis; Agnatha) reddening syndrome in Southland rivers, New Zealand 2011-2013: laboratory findings and epidemiology, including the incidental detection of an atypical Aeromonas salmonicida
Published in New Zealand journal of marine and freshwater research (03-07-2019)“…From 2011, lamprey (Geotria australis) populations in Southland, New Zealand have been affected by reddening along the length of the body and increased…”
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Using chemical and DNA marker analysis to authenticate a high-value food, manuka honey
Published in NPJ science of food (22-05-2018)“…Ensuring the authenticity of food is a rapidly emerging issue, especially in regard to high-value products that are marketed through increasingly complex…”
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Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3‑Kinase δ for the Treatment of Respiratory Disease
Published in Journal of medicinal chemistry (24-09-2015)“…Optimization of lead compound 1, through extensive use of structure-based design and a focus on PI3Kδ potency, isoform selectivity, and inhaled PK properties,…”
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The Squalestatins: Decarboxy and 4-Deoxy Analogues as Potent Squalene Synthase Inhibitors
Published in Journal of medicinal chemistry (05-01-1996)“…Squalestatins without either the hydroxy group at C-4 or the carboxylic acid at C-3 or C-4 were prepared and evaluated for their ability to inhibit rat liver…”
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The discovery and synthesis of highly potent, A 2a receptor agonists
Published in Bioorganic & medicinal chemistry letters (01-02-2000)Get full text
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Inhibitors of cholesterol biosynthesis. 1. 3,5-Dihydroxy-7-(N-imidazolyl)-6-heptenoates and -heptanoates, a novel series of HMG-CoA reductase inhibitors
Published in Journal of medicinal chemistry (12-11-1993)“…3,5-Dihydroxy-7-(N-imidazolyl)heptanoates 4 and the corresponding heptenoates 5 were synthesized as novel classes of potent HMG-CoA reductase (HMGR) inhibitors…”
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