The Circumferential Loading of a Direct Cardiac Compression Assist Device

The Circumferential Loading of a Direct Cardiac Compression Assist Device

Heart disease is the developed world's largest killer. Transplantation of the failing heart remains the most effective treatment currently employed, but demand far exceeds donor supply. In a bid to address this imbalance, the use of mechanical circulatory support has been explored since the mid...

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Bibliographic Details
Published in:2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Vol. 2007; pp. 1031 - 1034
Main Authors: Keeling, D.G., Levesley, M.C., Walker, P.G., Hanson, B.M., Watterson, K., Pereni, C.I., Jaber, O.
Format: Conference Proceeding Journal Article
Language:English
Published: United States IEEE 01-01-2007
Subjects:
Actuators
Blood Flow Velocity - physiology
Blood Pressure - physiology
Cardiac disease
Cardiovascular diseases
Compressive Strength
Computational modeling
Computer Simulation
Computer-Aided Design
Equipment Design
Equipment Failure Analysis
Filling
Friction
Heart
Heart - physiology
Heart-Assist Devices
In vitro
Models, Cardiovascular
Muscles
Supply and demand
Surface treatment
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Summary:Heart disease is the developed world's largest killer. Transplantation of the failing heart remains the most effective treatment currently employed, but demand far exceeds donor supply. In a bid to address this imbalance, the use of mechanical circulatory support has been explored since the mid-1960s. This paper utilizes one such device, which achieves assistance by mechanically compressing the epicardial surface of the failing heart. The circumferential normal loading of the device is investigated, showing how frictional effects inherent to the device's operation affect localized surface pressure. Results showed that as distance from the device's actuator increased, assistive systolic force reduced, whilst device constriction to ventricular filling detrimentally increased. Active device relaxation was shown to limit the diastolic effect outlined above, providing the simulated diseased heart with an improved cardiac output. The results also raise questions concerning device in-vivo positioning and short-comings with the current heart simulator.
ISBN:9781424407873
1424407877
ISSN:1094-687X
1557-170X
1558-4615
DOI:10.1109/IEMBS.2007.4352470