Search Results - "Keelan, J.A"

Pharmacological inhibition of inflammatory pathways for the prevention of preterm birth by Keelan, J.A

“…Abstract The major cause of spontaneous preterm birth (sPTB) at less than 32 weeks of gestation is intrauterine inflammation as a consequence of colonisation…”
Get full text

Pharmacological inhibition of inflammatory pathways for prevention of preterm birth by Keelan, J.A

Get full text

Trans-placental passage and anti-inflammatory effects of solithromycin in the human placenta by Keelan, J.A, Pugazhenthi, K

“…Abstract Introduction Solithromycin is a 4th generation macrolide/fluoroketolide antibiotic that has potential applications in the treatment and prevention of…”
Get full text

The inflammatory state of the rat placenta increases in late gestation and is further enhanced by glucocorticoids in the labyrinth zone by Mark, P.J, Lewis, J.L, Jones, M.L, Keelan, J.A, Waddell, B.J

“…Abstract Introduction Inflammation plays central roles in key aspects of successful reproduction: ovulation, implantation and parturition. In this study we…”
Get full text

Cytokines of the Placenta and Extra-placental Membranes: Roles and Regulation During Human Pregnancy and Parturition by Bowen, J.M., Chamley, L., Keelan, J.A., Mitchell, M.D.

“…Summary In an earlier, companion, review, we concluded that cytokines produced by the placenta and associated membranes are likely to be involved in control of…”
Get full text

Effects of omega-3 and omega-6 fatty acids on human placental cytokine production by Melody, S.M, Vincent, R, Mori, T.A, Mas, E, Barden, A.E, Waddell, B.J, Keelan, J.A

“…Abstract Introduction Dietary supplementation with omega-3 long chain polyunsaturated fatty acids ( n -3 PUFAs) may exert benefits in pregnancy through…”
Get full text

Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors by Aye, I.L.M.H, Waddell, B.J, Mark, P.J, Keelan, J.A

“…Abstract Oxygenated cholesterol metabolites known as oxysterols display potent biological activities ranging from regulation of lipid homeostasis to…”
Get full text

Cytokines of the Placenta and Extra-placental Membranes: Biosynthesis, Secretion and Roles in Establishment of Pregnancy in Women by Bowen, J.M., Chamley, L., Mitchell, M.D., Keelan, J.A.

“…Virtually all known cytokines have been demonstrated to be expressed in the placenta and associated fetal and maternal membranes during normal gestation. In…”
Get full text

The Xenobiotic Transporter ABCG2 Plays a Novel Role in Differentiation of Trophoblast-like BeWo Cells by Evseenko, D.A, Paxton, J.W, Keelan, J.A

“…Abstract Trophoblast cells undergo loss of plasma membrane lipid asymmetry during cell fusion without further progression to terminal phases of apoptosis. The…”
Get full text

Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation by Chui, A, Evseenko, D.A, Brennecke, S.P, Keelan, J.A, Kalionis, B, Murthi, P

“…Abstract Dlx3, a member of the large homeobox gene family of transcription factors, is important for murine placental development. Targeted deletion of Dlx3 in…”
Get full text

Expression, Localisation and Activity of ATP Binding Cassette (ABC) Family of Drug Transporters in Human Amnion Membranes by Aye, I.L.M.H, Paxton, J.W, Evseenko, D.A, Keelan, J.A

“…Abstract Placental ATP-binding cassette (ABC) transporters limit fetal exposure to xenobiotics by regulating transplacental passage into the fetal circulation;…”
Get full text

ABCA1 and placental cholesterol efflux by Keelan, J.A, Aye, I.L.M.H, Mark, P.J, Waddell, B.J

Get full text

Testicular function in a birth cohort of young men by Hart, R.J., Doherty, D.A., McLachlan, R.I., Walls, M.L., Keelan, J.A., Dickinson, J.E., Skakkebaek, N.E., Norman, R.J., Handelsman, D.J.

Get full text

IFPA Meeting 2009 Workshops Report by Lash, G.E, Burton, G.J, Chamley, L.W, Clifton, V.L, Constancia, M, Crocker, I.P, Dantzer, V, Desoye, G, Drewlo, S, Hemmings, D.G, Hiendleder, S, Kalionis, B, Keelan, J.A, Kudo, Y, Lewis, R.M, Manuelpillai, U, Murthi, P, Natale, D, Pfarrer, C, Robertson, S, Saffery, R, Saito, S, Sferruzzi-Perri, A, Sobrevia, L, Waddell, B.J, Roberts, C.T

“…Abstract Workshops are an important part of the annual meeting of the International Federation of Placenta Associations (IFPA). At IFPA Meeting 2009 diverse…”
Get full text

Activin A Exerts both Pro- and Anti-inflammatory Effects on Human Term Gestational Tissues by Keelan, J.A., Zhou, R.-L., Mitchell, M.D.

“…There is a growing appreciation of the importance of activin as a modulator of immune function. The aim of the present study was to determine whether activin A…”
Get full text

Identification and removal of contaminating microbial DNA from PCR reagents: impact on low‐biomass microbiome analyses by Stinson, L.F., Keelan, J.A., Payne, M.S.

“…Reagent‐derived contamination can compromise the integrity of microbiome data, particularly in low microbial biomass samples. This contamination has recently…”
Get full text

In vitro maturation as an alternative to standard in vitro fertilization for patients diagnosed with polycystic ovaries: a comparative analysis of fresh, frozen and cumulative cycle outcomes by Walls, M.L., Hunter, T., Ryan, J.P., Keelan, J.A., Nathan, E., Hart, R.J.

“…STUDY QUESTION Is in vitro maturation (IVM) as successful as standard in vitro fertilization (IVF) for the treatment of patients with polycystic ovaries (PCO)…”
Get full text

Testicular function in a birth cohort of young men by Hart, R.J., Doherty, D.A., McLachlan, R.I., Walls, M.L., Keelan, J.A., Dickinson, J.E., Skakkebaek, N.E., Norman, R.J., Handelsman, D.J.

“…STUDY QUESTION By investigating a birth cohort with a high ongoing participation rate to derive an unbiased population, what are the parameters and influences…”
Get full text

In vitro maturation is associated with increased early embryo arrest without impairing morphokinetic development of useable embryos progressing to blastocysts by Walls, M.L., Ryan, J.P., Keelan, J.A., Hart, R.

“…STUDY QUESTIONS Does polycystic ovarian syndrome (PCOS) or in vitro maturation (IVM) treatment affect embryo development events and morphokinetic parameters…”
Get full text

Characterization of the bacterial microbiome in first‐pass meconium using propidium monoazide (PMA) to exclude nonviable bacterial DNA by Stinson, L.F., Keelan, J.A., Payne, M.S.

“…Numerous studies have reported bacterial DNA in first‐pass meconium samples, suggesting that the human gut microbiome is seeded prior to birth. However, these…”
Get full text