CD40mAb adjuvant induces a rapid antibody response that may be beneficial in post-exposure prophylaxis
Active vaccination can be effective as a post-exposure prophylaxis, but the rapidity of the immune response induced, relative to the incubation time of the pathogen, is critical. We show here that CD40mAb conjugated to antigen induces a more rapid specific antibody response than currently used immun...
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Published in: | Journal of immune based therapies and vaccines Vol. 8; no. 1; p. 1 |
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Main Authors: | , , , , , |
Format: | Journal Article |
Language: | English |
Published: |
England
BioMed Central Ltd
04-02-2010
BioMed Central |
Subjects: | |
Online Access: | Get full text |
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Summary: | Active vaccination can be effective as a post-exposure prophylaxis, but the rapidity of the immune response induced, relative to the incubation time of the pathogen, is critical. We show here that CD40mAb conjugated to antigen induces a more rapid specific antibody response than currently used immunological adjuvants, alum and monophosphoryl lipid A. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1476-8518 1476-8518 |
DOI: | 10.1186/1476-8518-8-1 |