Search Results - "Keefe, Lisa"

FakeMeat: How big a deal will animal meat analogs ultimately be? by Keefe, Lisa M

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Accelerating pharmaceutical structure-guided drug design: a successful model by Keefe, Lisa J., Stoll, Vincent S.

“…•Quality, reliability, speed, and security ensure success in drug discovery.•Routine, frequent, fast data collection provide cost-effective value to…”
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Polo: an open‐source graphical user interface for crystallization screening by Holleman, Ethan T., Duguid, Erica, Keefe, Lisa J., Bowman, Sarah E. J.

“…Polo is a Python‐based graphical user interface designed to streamline viewing and analysis of images to monitor crystal growth, with a specific target to…”
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Global radiation damage: temperature dependence, time dependence and how to outrun it by Warkentin, Matthew, Hopkins, Jesse B., Badeau, Ryan, Mulichak, Anne M., Keefe, Lisa J., Thorne, Robert E.

“…A series of studies that provide a consistent and illuminating picture of global radiation damage to protein crystals, especially at temperatures above ∼200 K,…”
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Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes by Edwards, Megan R., Liu, Hejun, Shabman, Reed S., Ginell, Garrett M., Luthra, Priya, Ramanan, Parmeshwaran, Keefe, Lisa J., Köllner, Bernd, Amarasinghe, Gaya K., Taylor, Derek J., Leung, Daisy W., Basler, Christopher F.

“…Non-retroviral integrated RNA viral sequences (NIRVs) potentially encoding ∼280 amino acid homologs to filovirus VP35 proteins are present across the Myotis…”
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Structure of the Neurospora SET Domain Protein DIM-5, a Histone H3 Lysine Methyltransferase by Zhang, Xing, Tamaru, Hisashi, Khan, Seema I., Horton, John R., Keefe, Lisa J., Selker, Eric U., Cheng, Xiaodong

“…AdoMet-dependent methylation of histones is part of the “histone code” that can profoundly influence gene expression. We describe the crystal structure of…”
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Towards protein-crystal centering using second-harmonic generation (SHG) microscopy by Kissick, David J., Dettmar, Christopher M., Becker, Michael, Mulichak, Anne M., Cherezov, Vadim, Ginell, Stephan L., Battaile, Kevin P., Keefe, Lisa J., Fischetti, Robert F., Simpson, Garth J.

“…The potential of second‐harmonic generation (SHG) microscopy for automated crystal centering to guide synchrotron X‐ray diffraction of protein crystals was…”
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Preparing veterinary students for entry-level practice by identifying new graduate outcomes by Rogers, Kenita S, Green, Eleanor M, Chaney, Kristin P, Macik, Maria L, Turner, Jacqueline S, Keefe, Lisa M, Scallan, Elizabeth M, Korich, Jodi A, Fowler, Debra

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Curriculum Redesign in Veterinary Medicine: Part I by Chaney, Kristin P, Macik, Maria L, Turner, Jacqueline S, Korich, Jodi A, Rogers, Kenita S, Fowler, Debra, Scallan, Elizabeth M, Keefe, Lisa M

“…Curricular review is considered a necessary component for growth and enhancement of academic programs and requires time, energy, creativity, and persistence…”
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Mini-beam collimator applications at the Advanced Photon Source by Xu, Shenglan, Keefe, Lisa J., Mulichak, Anne, Yan, Lifen, Alp, Ercan E., Zhao, Jiyong, Fischetti, Robert F.

“…In 2007, the General Medicine and Cancer Institutes Collaborative Access Team (GM/CA CAT, Sector 23, Advanced Photon Source) began providing mini-beam…”
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Curriculum Redesign in Veterinary Medicine: Part II by Macik, Maria L, Chaney, Kristin P, Turner, Jacqueline S, Rogers, Kenita S, Scallan, Elizabeth M, Korich, Jodi A, Fowler, Debra, Keefe, Lisa M

“…Curricular review is considered a necessary component for growth and enhancement of academic programs and requires time, energy, creativity, and persistence…”
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Linear fitting of multi-threshold counting data with a pixel-array detector for spectral X-ray imaging by Muir, Ryan D., Pogranichney, Nicholas R., Muir, J. Lewis, Sullivan, Shane Z., Battaile, Kevin P., Mulichak, Anne M., Toth, Scott J., Keefe, Lisa J., Simpson, Garth J.

“…Experiments and modeling are described to perform spectral fitting of multi‐threshold counting measurements on a pixel‐array detector. An analytical model was…”
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From lab to leadership: pursuing passion and purpose by Keefe, Lisa J.

“…Abstract only…”
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Global radiation damage at 300 and 260 K with dose rates approaching 1 MGy s by Warkentin, Matthew, Badeau, Ryan, Hopkins, Jesse B, Mulichak, Anne M, Keefe, Lisa J, Thorne, Robert E

“…Global radiation damage to 19 thaumatin crystals has been measured using dose rates from 3 to 680 kGy s⁻¹. At room temperature damage per unit dose appears to…”
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Focusing, collimation and flux throughput at the IMCA-CAT bending-magnet beamline at the Advanced Photon Source by Koshelev, Irina, Huang, Rong, Graber, Timothy, Meron, Mati, Muir, J. Lewis, Lavender, William, Battaile, Kevin, Mulichak, Anne M., Keefe, Lisa J.

“…The IMCA‐CAT bending‐magnet beamline was upgraded with a collimating mirror in order to achieve the energy resolution required to conduct high‐quality multi‐…”
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IMCA-CAT: accelerating drug discovery through synchrotron-based structural biology by Keefe, Lisa J.

“…Abstract only…”
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The use of harvested white-tailed deer (Odocoileus virginianus) and geographic information system (GIS) methods to characterize distribution and locate spatial clusters of Borrelia burgdorferi and its vector Ixodes scapularis in Indiana by Keefe, Lisa M, Moro, Manuel H, Vinasco, Javier, Hill, Catherine, Wu, Ching C, Raizman, Eran A

“…Ixodes scapularis (Say) is the vector for Borrelia burgdorferi (Bb) the causative agent of Lyme disease (LD). The increased number and presence of ticks in the…”
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The Creation of a Collaborative, Case-Based Learning Experience in a Large-Enrollment Classroom by Tayce, Jordan D, Saunders, Ashley B, Keefe, Lisa, Korich, Jodi

“…Numerous educational studies have shown that passive learning methods are frequently associated with disappointing learning outcomes, yet many faculty…”
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Advancing structure-based drug design: IMCA-CAT responds to emerging needs of the pharmaceutical industry by Yoder, Jesse, Mulichak, Anne M., Muir, J. Lewis, Zoellner, Eric, Digilio, Joe, Duguid, Erica, Keefe, Lisa

“…Abstract only…”
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APS-U update and structural biology future directions by Fischetti, Robert, Venugopalan, Nagarajan, Srajer, Vukica, Henning, Robert, Keefe, Lisa, Joachimiak, Andrzej, Michalska, Karolina, Anderson, Spencer, Brunzelle, Joseph S., Chrzas, John, Rose, John, Capel, Malcolm, Benach, Jordi

“…Abstract only…”
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