Search Results - "Keech, Cheryl"

Phase 1–2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine by Keech, Cheryl, Albert, Gary, Cho, Iksung, Robertson, Andreana, Reed, Patricia, Neal, Susan, Plested, Joyce S, Zhu, Mingzhu, Cloney-Clark, Shane, Zhou, Haixia, Smith, Gale, Patel, Nita, Frieman, Matthew B, Haupt, Robert E, Logue, James, McGrath, Marisa, Weston, Stuart, Piedra, Pedro A, Desai, Chinar, Callahan, Kathleen, Lewis, Maggie, Price-Abbott, Patricia, Formica, Neil, Shinde, Vivek, Fries, Louis, Lickliter, Jason D, Griffin, Paul, Wilkinson, Bethanie, Glenn, Gregory M

“…A recombinant SARS-CoV-2 spike protein nanoparticle vaccine delivered in the deltoid muscle on days 0 and 21 was found to be immunogenic at both 5 μg and 25 μg…”
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A Phase 1 Randomized, Placebo-controlled, Observer-blinded Trial to Evaluate the Safety and Immunogenicity of Inactivated Streptococcus pneumoniae Whole-cell Vaccine in Adults by Keech, Cheryl A., Morrison, Royce, Anderson, Porter, Tate, Andrea, Flores, Jorge, Goldblatt, David, Briles, David, Hural, John, Malley, Richard, Alderson, Mark R.

“…BACKGROUND:Broadly protective pneumococcal vaccines that are affordable for low-resource countries are needed. Streptococcus pneumoniae whole cell vaccine…”
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Advances in RSV vaccine research and development – A global agenda by Higgins, Deborah, Trujillo, Carrie, Keech, Cheryl

“…Highlights • RSV is a significant annual cause of lower respiratory tract illness globally. • Pediatric and elderly populations are most vulnerable, but no…”
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Year-by-year analysis of cardiovascular events in the Multiple Outcomes of Raloxifene Evaluation (MORE) trial by Keech, Cheryl A., Sashegyi, Andreas, Barrett-Connor, Elizabeth

“…ABSTRACT Objective: To assess the effect of raloxifene 60 mg/day (RLX) on year-by-year cardiovascular (CV) events in postmenopausal women participating in the…”
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Safety assessment of raloxifene over eight years in a clinical trial setting by Martino, Silvana, Disch, Damon, Dowsett, Sherie A., Keech, Cheryl A., Mershon, John L.

“…ABSTRACT Objective: Osteoporosis is a chronic disorder that warrants long-term therapy. If benefits are to outweigh risks, the long-term safety profiles of…”
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Vascular events in the Multiple Outcomes of Raloxifene Evaluation (MORE) trial: incidence, patient characteristics, and effect of raloxifene by Duvernoy, Claire S, Kulkarni, Pandurang M, Dowsett, Sherie A, Keech, Cheryl A

“…OBJECTIVE:To determine the incidence of arterial and venous thromboembolic (VTE) events, to determine the effect of raloxifene on the incidence of combined…”
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Carotid artery intima-media thickness after raloxifene treatment by Mack, Wendy J, Dhungana, Bala, Dowsett, Sherie A, Keech, Cheryl A, Feng, Mei, Li, Yanjie, Hodis, Howard N

“…Raloxifene, a selective estrogen receptor modulator (SERM), decreases total and low-density lipoprotein cholesterol (LDL-C) in postmenopausal women and…”
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Effects of raloxifene and low-dose simvastatin coadministration on plasma lipids in postmenopausal women with primary hypercholesterolemia by Insull, William, Davidson, Michael H., Kulkarni, Pandurang M., Siddhanti, Suresh, Ciaccia, Angelina V., Keech, Cheryl A.

“…Raloxifene and low-dose simvastatin can each reduce low-density lipoprotein (LDL) cholesterol without affecting high-density lipoprotein (HDL) cholesterol and…”
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Stillbirth: Case definition and guidelines for data collection, analysis, and presentation of maternal immunization safety data by Tavares Da Silva, Fernanda, Gonik, Bernard, McMillan, Mark, Keech, Cheryl, Dellicour, Stephanie, Bhange, Shraddha, Tila, Mihaela, Harper, Diana M, Woods, Charles, Kawai, Alison Tse, Kochhar, Sonali, Munoz, Flor M

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Comparison of the safety and immunogenicity of a novel Matrix-M-adjuvanted nanoparticle influenza vaccine with a quadrivalent seasonal influenza vaccine in older adults: a phase 3 randomised controlled trial by Shinde, Vivek, Cho, Iksung, Plested, Joyce S, Agrawal, Sapeckshita, Fiske, Jamie, Cai, Rongman, Zhou, Haixia, Pham, Xuan, Zhu, Mingzhu, Cloney-Clark, Shane, Wang, Nan, Zhou, Bin, Lewis, Maggie, Price-Abbott, Patty, Patel, Nita, Massare, Michael J, Smith, Gale, Keech, Cheryl, Fries, Louis, Glenn, Gregory M

“…Improved seasonal influenza vaccines for older adults that can induce broadly cross-reactive antibodies and enhanced T-cell responses, particularly against A…”
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Immunogenicity and safety of BPZE1, an intranasal live attenuated pertussis vaccine, versus tetanus–diphtheria–acellular pertussis vaccine: a randomised, double-blind, phase 2b trial by Keech, Cheryl, Miller, Vicki E, Rizzardi, Barbara, Hoyle, Christopher, Pryor, Melinda J, Ferrand, Jonathan, Solovay, Ken, Thalen, Marcel, Noviello, Stephanie, Goldstein, Peter, Gorringe, Andrew, Cavell, Breeze, He, Qiushui, Barkoff, Alex-Mikael, Rubin, Keith, Locht, Camille

“…Bordetella pertussis epidemics persist as transmission remains unabated despite high acellular pertussis vaccination rates. BPZE1, a live attenuated intranasal…”
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Respiratory distress in the neonate: Case definition & guidelines for data collection, analysis, and presentation of maternal immunization safety data by Sweet, Leigh R., Keech, Cheryl, Klein, Nicola P., Marshall, Helen S., Tagbo, Beckie N., Quine, David, Kaur, Pawandeep, Tikhonov, Ilia, Nisar, Muhammad Imran, Kochhar, Sonali, Muñoz, Flor M.

“…According to the American Academy of Pediatrics, approximately 10% of neonates need some assistance to begin breathing at birth, with up to 1% requiring…”
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1183. Serum Bactericidal Activity Induced by Live Attenuated Pertussis Vaccine BPZE1 is Comparable to Boostrix by Keech, Cheryl A, Gorringe, Andrew, Cavell, Breeze, Goldstein, Peter, Rubin, Keith

“…Abstract Background In a Phase 2b, multi-center, placebo-controlled, randomized study, intranasal BPZE1 induced mucosal and serum antibodies to pertussis…”
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Gestational diabetes mellitus: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data by Kachikis, Alisa, Eckert, Linda O., Walker, Christie, Oteng-Ntim, Eugene, Guggilla, Rama, Gupta, Manish, Patwardhan, Manasi, Mataya, Ronald, Mallett Moore, Tamala, Alguacil-Ramos, Ana Maria, Keech, Cheryl, Gravett, Michael, Murphy, Helen, Kochhar, Sonali, Chescheir, Nancy

“…According to the International Diabetes Federation (IDF), about 16.8% of live-births are born to women with hyperglycemia in pregnancy [1]. Ideally, studies…”
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Effects of raloxifene on lipid and lipoprotein levels in postmenopausal osteoporotic women with and without hypertriglyceridemia by Dayspring, Thomas, Qu, Yongming, Keech, Cheryl

“…This post hoc analysis reports the effects of raloxifene on lipids and lipoproteins in 2659 women with either normal (≤150 mg/dL) or high (>150 mg/dL)…”
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1047-186 Raloxifene improves lipoprotein, apolipoprotein and fibrinogen in postmenopausal osteoporotic women with or without hypertriglyceridemia by Dayspring, Thomas, Qu, Yongming, Keech, Cheryl A

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Interaction of basal positive and negative transcription elements controls repression of the proximal rat prolactin promoter in nonpituitary cells by Jackson, S M, Keech, C A, Williamson, D J, Gutierrez-Hartmann, A

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cyclic adenosine 3',5'-monophosphate activation of the rat prolactin promoter is restricted to the pituitary-specific cell type by Keech, C A, Jackson, S M, Siddiqui, S K, Ocran, K W, Gutierrez-Hartmann, A

“…Pituitary lactotroph cell function and PRL gene expression are highly regulated by the cAMP-protein kinase-A (PKA) pathway. To further our understanding of the…”
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Insulin activation of rat prolactin promoter activity by Keech, C A, Gutierrez-Hartmann, A

“…The role of insulin regulation of rat prolactin (rPRL) gene transcription was studied using GH4 rat pituitary tumor cells transiently transfected with plasmids…”
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Interaction of Basal Positive and Negative Transcription Elements Controls Repression of the Proximal Rat Prolactin Promoter in Nonpituitary Cells by Jackson, Stephen M., Keech, Cheryl A., Williamson, Douglas J., Gutierrez-Hartmann, Arthur

“…The proximal rat prolactin (rPRL) promoter contains three cell-specific elements, designated footprints I, III, and IV, which restrict rPRL gene expression to…”
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