Search Results - "Keeble, E."

The functions of TRPA1 and TRPV1: moving away from sensory nerves by Fernandes, ES, Fernandes, MA, Keeble, JE

“…The transient receptor potential vanilloid 1 and ankyrin 1 (TRPV1 and TRPA1, respectively) channels are members of the TRP superfamily of structurally related,…”
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The sympathetic nervous system is controlled by transient receptor potential vanilloid 1 in the regulation of body temperature by Alawi, Khadija M., Aubdool, Aisah A., Liang, Lihuan, Wilde, Elena, Vepa, Abhinav, Psefteli, Maria‐Paraskevi, Brain, Susan D., Keeble, Julie E.

“…ABSTRACT Transient receptor potential vanilloid 1 (TRPV1) is involved in sensory nerve nociceptive signaling. Recently, it has been discovered that TRPV1…”
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TRPV1 deletion enhances local inflammation and accelerates the onset of systemic inflammatory response syndrome by Fernandes, Elizabeth S, Liang, Lihuan, Smillie, Sarah-Jane, Kaiser, Frank, Purcell, Robert, Rivett, Damian W, Alam, Saydul, Howat, Sarah, Collins, Helen, Thompson, Stephen J, Keeble, Julie E, Riffo-Vasquez, Yanira, Bruce, Kenneth D, Brain, Susan D

“…The transient receptor potential vanilloid 1 (TRPV1) is primarily localized to sensory nerve fibers and is associated with the stimulation of pain and…”
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Pharmacology and potential therapeutic applications of nitric oxide‐releasing non‐steroidal anti‐inflammatory and related nitric oxide‐donating drugs by Keeble, J E, Moore, P K

“…This review examines the biological significance, therapeutic potential and mechanism(s) of action of a range of nitric oxide‐releasing non‐steroidal…”
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Presentation, treatment and outcome of long‐bone fractures in pet rabbits (Oryctolagus cuniculus) by Garcia‐Pertierra, S., Ryan, J., Richardson, J., Koterwas, B., Keeble, E., Eatwell, K., Clements, D. N.

“…Objectives To describe the incidence, aetiology, characteristics, assessment, management and outcome of long‐bone fractures in rabbits presenting to a single…”
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Husbandry risk factors associated with hock pododermatitis in UK pet rabbits (Oryctolagus cuniculus) by Mancinelli, E., Keeble, E., Richardson, J., Hedley, J.

“…Pododermatitis, often called ‘sore hocks’, is a chronic, granulomatous, ulcerative dermatitis which most commonly affects the plantar aspect of the caudal…”
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Femoral condylar fractures in four continental giant breed rabbits by Dorlis, C., Garcia‐Pertierra, S., Richardson, J., Koterwas, B., Keeble, E., Eatwell, K., Ryan, J., Clements, D. N.

“…Four male neutered continental giant rabbits aged between 10 and 30 months were presented with femoral condylar fractures, which developed without an observed…”
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Seroprevalence of antibodies to Encephalitozoon cuniculi in domestic rabbits in the United Kingdom by Keeble, E. J., Shaw, D. J.

“…Serum samples from 97 clinically healthy domestic rabbits were tested for antibodies to Encephalitozoon cuniculi by an indirect ELISA technique. Fifty (52 per…”
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Divergent Relationships between Fecal Microbiota and Metabolome following Distinct Antibiotic-Induced Disruptions by Choo, Jocelyn M, Kanno, Tokuwa, Zain, Nur Masirah Mohd, Leong, Lex E X, Abell, Guy C J, Keeble, Julie E, Bruce, Kenneth D, Mason, A James, Rogers, Geraint B

“…The intestinal microbiome plays an essential role in regulating many aspects of host physiology, and its disruption through antibiotic exposure has been…”
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Partial ear canal ablation and lateral bulla osteotomy in rabbits by Eatwell, K., Mancinelli, E., Hedley, J., Keeble, E., Kovalik, M., Yool, D. A.

“…Six lop rabbits were presented with clinical signs of otitis media or externa. The presence of disease was confirmed by computerized tomography examination,…”
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Participation of peripheral tachykinin NK1 receptors in the carrageenan-induced inflammation of the rat temporomandibular joint by Denadai-Souza, Alexandre, Camargo, Livia de Lucca, Ribela, Maria T.C.P, Keeble, Julie E, Costa, Soraia K.P, Muscará, Marcelo N

“…Abstract Temporomandibular disorders represent one of the major challenges in dentistry therapeutics. This study was undertaken to evaluate the time course of…”
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A role for substance P in arthritis? by Keeble, J.E., Brain, S.D.

“…Substance P is a neuropeptide that is released from sensory nerves and which has a number of pro-inflammatory effects. In this article, we review the evidence…”
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Medical management of Trichophyton dermatophytosis using a novel treatment regimen in L'Hoest's monkeys (Cercopithecus lhoesti) by Keeble, E. J., Neuber, A., Hume, L., Goodman, G.

“…An outbreak of Trichophyton dermatophytosis was diagnosed in a group of four L'Hoest's monkeys (Cercopithecus lhoesti) housed in the primate section at a…”
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Encephalitozoon cuniculi in rabbits by Keeble, E

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Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner by Fernandes, Elizabeth S, Russell, Fiona A, Alawi, Khadija M, Sand, Claire, Liang, Lihuan, Salamon, Robin, Bodkin, Jennifer V, Aubdool, Aisah A, Arno, Matthew, Gentry, Clive, Smillie, Sarah-Jane, Bevan, Stuart, Keeble, Julie E, Malcangio, Marzia, Brain, Susan D

“…The effect of cold temperature on arthritis symptoms is unclear. The aim of this study was to investigate how environmental cold affects pain and blood flow in…”
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Suspected allergic reaction to penicillamine in mute swans by Keeble, E

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Endocrine diseases in small mammals by Keeble, Emma

“…ALTHOUGH endocrine diseases of small pet mammals are frequently encountered in veterinary practice, they are only rarely reported in the literature and may,…”
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Tumour necrosis factor α mediates transient receptor potential vanilloid 1-dependent bilateral thermal hyperalgesia with distinct peripheral roles of interleukin-1β, protein kinase C and cyclooxygenase-2 signalling by Russell, Fiona A., Fernandes, Elizabeth S., Courade, Jean-Philippe, Keeble, Julie E., Brain, Susan D.

“…TNFα plays a pivotal role in rheumatoid arthritis (RA) but little is known of the mechanisms that link the inflammatory and nociceptive effects of TNFα. We…”
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Effects of epidermal growth factor, interleukin 1 and nitric oxide on prostaglandin production by guinea-pig uterus by Keeble, JE, Poyser, NL

“…Initial experiments in the present study investigated the effects of epidermal growth factor (EGF), interleukin 1beta (IL-1beta) and sodium nitroprusside (a…”
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Outcomes of hospital admissions among frail older people: a 2-year cohort study by Keeble, Eilís, Roberts, Helen C, Williams, Christopher D, Van Oppen, James, Conroy, Simon Paul

“…'Frailty crises' are a common cause of hospital admission among older people and there is significant focus on admission avoidance. However, identifying…”
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