Search Results - "Keebaugh, Erin S."
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Lactobacilli Modulate Epithelial Cytoprotection through the Nrf2 Pathway
Published in Cell reports (Cambridge) (25-08-2015)“…An optimal gut microbiota influences many beneficial processes in the metazoan host. However, the molecular mechanisms that mediate and function in…”
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The Nutritional Environment Influences the Impact of Microbes on Drosophila melanogaster Life Span
Published in mBio (09-07-2019)“…Microbes can extend life span by contributing to the nutritional value of malnourishing fly culture medium. The beneficial effect of microbes during…”
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Microbial Quantity Impacts Drosophila Nutrition, Development, and Lifespan
Published in iScience (29-06-2018)“…In Drosophila, microbial association can promote development or extend life. We tested the impact of microbial association during malnutrition and show that…”
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Microbes without Borders: Decompartmentalization of the Aging Gut
Published in Cell host & microbe (10-02-2016)“…The microbiota supports intestinal homeostasis in developing animals. With increased age, gut maintenance declines and microbes can stray from traditional…”
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Mgat1-dependent N-glycosylation of membrane components primes Drosophila melanogaster blood cells for the cellular encapsulation response
Published in PLoS pathogens (01-07-2012)“…In nature, larvae of the fruitfly Drosophila melanogaster are commonly infected by parasitoid wasps, and so have evolved a robust immune response to counter…”
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Evolutionary responses of Drosophila melanogaster under chronic malnutrition
Published in Frontiers in ecology and evolution (01-04-2018)“…species have successfully spread and adapted to diverse climates across the globe. For , rotting vegetative matter provides the primary substrate for mating…”
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Diet influences host–microbiota associations in Drosophila
Published in Proceedings of the National Academy of Sciences - PNAS (15-05-2018)“…Gut microbes were previously suggested to influence mate preference in Drosophila melanogaster. Mate selectivity depended on the microbiota associated with…”
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Insights from natural host-parasite interactions: the Drosophila model
Published in Developmental and comparative immunology (01-01-2014)“…Immune responses against opportunistic pathogens have been extensively studied in Drosophila, leading to a detailed map of the genetics behind innate immunity…”
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Nutrition Influences Caffeine-Mediated Sleep Loss in Drosophila
Published in Sleep (New York, N.Y.) (01-11-2017)“…Plant-derived caffeine is regarded as a defensive compound produced to prevent herbivory. Caffeine is generally repellent to insects and often used to study…”
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Fruit flies diversify their offspring in response to parasite infection
Published in Science (American Association for the Advancement of Science) (14-08-2015)“…The evolution of sexual reproduction is often explained by Red Queen dynamics: Organisms must continually evolve to maintain fitness relative to interacting…”
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Breaking Down Walls: Microbiota and the Aging Gut
Published in Cell host & microbe (12-04-2017)“…A range of animal species show increased inflammation with age. In this issue of Cell Host & Microbe, Thevaranjan et al. (2017) reveal that heightened…”
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Extracellular matrix protein N-glycosylation mediates immune self-tolerance in Drosophila melanogaster
Published in Proceedings of the National Academy of Sciences - PNAS (28-09-2021)“…In order to respond to infection, hosts must distinguish pathogens from their own tissues. This allows for the precise targeting of immune responses against…”
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Mifepristone Reduces Food Palatability and Affects Drosophila Feeding and Lifespan
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-02-2017)“…The Drosophila GeneSwitch system facilitates the spatial and temporal control of gene expression through dietary supplementation of mifepristone (RU486)…”
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Adaptive Evolution of a Novel Drosophila Lectin Induced by Parasitic Wasp Attack
Published in Molecular biology and evolution (01-02-2012)“…Drosophila melanogaster has long been used as a model for the molecular genetics of innate immunity. Such work has uncovered several immune receptors that…”
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15
Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase γ
Published in Laboratory investigation (01-04-2007)“…POLG is the human gene that encodes the catalytic subunit of DNA polymerase γ (Pol γ), the replicase for human mitochondrial DNA (mtDNA). A POLG Y955C point…”
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EVOLUTION. Fruit flies diversify their offspring in response to parasite infection
Published in Science (American Association for the Advancement of Science) (14-08-2015)“…The evolution of sexual reproduction is often explained by Red Queen dynamics: Organisms must continually evolve to maintain fitness relative to interacting…”
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17
Mgat1-dependent N-glycosylation of membrane components primes drosophila melanogaster blood cells for the cellular encapsulation response
Published in PLoS pathogens (01-07-2012)Get full text
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18
Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase
Published in Laboratory investigation (01-04-2007)“…POLG is the human gene that encodes the catalytic subunit of DNA polymerase gamma (Pol gamma), the replicase for human mitochondrial DNA (mtDNA). A POLG Y955C…”
Get full text
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