Search Results - "Kee, Boon Pin"
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The first association study of Protein Tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) gene polymorphisms in Malaysian patients with Crohn’s disease
Published in Gene (20-08-2022)“…•Five SNPs in PTPN2 were not significantly associated with CD in Malaysian patients.•Malaysian Chinese with rs487273 G/T genotype have a lower occurrence of…”
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Implementing HLA-B58:01 testing prior to allopurinol initiation in Malaysian primary care setting: A qualitative study from doctors' and patients' perspective
Published in PloS one (11-01-2024)“…Allopurinol, the first-line treatment for chronic gout, is a common causative drug for severe cutaneous adverse reactions (SCAR). HLA-B*58:01 allele was…”
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Identification of Plasmodium knowlesi Merozoite Surface Protein‐119 (PkMSP‐119) novel binding peptides from a phage display library
Published in Tropical medicine & international health (01-02-2020)“…Objective Plasmodium knowlesi, the fifth human malaria parasite, has caused mortality in humans. We aimed to identify P. knowlesi novel binding peptides…”
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Differential expression of small RNAs in biofilm-producing clinical methicillin-susceptible Staphylococcus aureus recovered from human urine
Published in Heliyon (30-10-2024)“…Bacterial small RNAs (sRNAs) play crucial roles in coordinating gene regulatory networks in various physiological processes, including biofilm formation. In…”
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Genetic polymorphisms of ATG16L1 and IRGM genes in Malaysian patients with Crohn's disease
Published in Journal of digestive diseases (01-01-2020)“…Objective To investigate the association between genetic polymorphisms in ATG16L1 and IRGM genes and the development of Crohn's disease (CD) in Malaysian…”
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Whole mitochondrial genome sequencing of Malaysian patients with cardiomyopathy
Published in PeerJ (San Francisco, CA) (14-04-2022)“…Cardiomyopathy (CMP) constitutes a diverse group of myocardium diseases affecting the pumping ability of the heart. Genetic predisposition is among the major…”
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The study of seroprevalence of hepatitis E virus and an investigation into the lifestyle behaviours of the aborigines in Malaysia
Published in Zoonoses and public health (01-05-2020)“…Malaysia is a non‐endemic country for hepatitis E virus (HEV) infection. However, seroprevalence as high as 50% among samples of aboriginal people were…”
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spa diversity of methicillin-resistant and -susceptible Staphylococcus aureus in clinical strains from Malaysia: a high prevalence of invasive European spa -type t032
Published in PeerJ (San Francisco, CA) (08-04-2021)“…is one of the important pathogens causing nosocomial infection. typing allows identification of clones in hospital isolates and is useful for epidemiological…”
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Phenotypic and molecular detection of biofilm formation in clinical methicillin-resistant Staphylococcus aureus isolates from Malaysia
Published in Journal of Taibah University for Science (31-12-2022)“…Methicillin-resistant Staphylococcus aureus (MRSA) is among the top threats to global public health and biofilm production is one of the factors attributed to…”
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Sequencing-based detection of 23S rRNA domain V mutations in treatment-naïve Helicobacter pylori patients from Malaysia
Published in Journal of global antimicrobial resistance. (01-12-2020)“…•Total of 37 point mutations were detected, including 6 known and 31 novel mutations.•Results support A2147G as a clinically significant point mutation.•Novel…”
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Plant-derived chimeric antibodies inhibit the invasion of human fibroblasts by Toxoplasma gondii
Published in PeerJ (San Francisco, CA) (11-12-2018)“…The parasite causes an opportunistic infection, that is, particularly severe in immunocompromised patients, infants, and neonates. Current antiparasitic drugs…”
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Association of NOD1, CXCL16, STAT6 and TLR4 gene polymorphisms with Malaysian patients with Crohn's disease
Published in PeerJ (San Francisco, CA) (31-03-2016)“…Crohn's disease (CD) is a prominent type of inflammatory bowel disease (IBD) that can affect any part of the gastrointestinal tract. CD is known to have higher…”
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Development of a species-specific PCR-RFLP targeting rpoD gene fragment for discrimination of Aeromonas species
Published in Journal of medical microbiology (01-09-2018)Get full text
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14
One-Step Differential Detection of OXA-48-Like Variants Using High-Resolution Melting (HRM) Analysis
Published in Antibiotics (Basel) (15-05-2020)“…OXA-48-like carbapenemase gene remains a hidden threat, as different OXA-48 variants have varying presentations of susceptibility to antibiotics that might…”
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Cloning and expression of a Vi mimotope of Salmonella enterica serovar Typhi through nucleotide-nucleotide hybridization approach
Published in African journal of biotechnology (15-09-2009)“…A recombinant His-Vi protein of Salmonella enterica serovar Typhi was successfully constructed and cloned into an expression vector through a…”
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Genetic variations of penicillin-binding protein 1A: insights into the current status of amoxicillin-based regimens for Helicobacter pylori eradication in Malaysia
Published in Journal of medical microbiology (01-05-2024)“…Resistance towards amoxicillin in causes significant therapeutic impasse in healthcare settings worldwide. In Malaysia, the standard treatment regimen includes…”
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Molecular identification and biofilm-forming ability of Elizabethkingia species
Published in Microbial pathogenesis (01-01-2022)“…Recently, Elizabethkingia species have gained attention as a cause of life-threatening infections. The identification via phenotypic methods of three important…”
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The phenotypes and genotypes associated with biofilm formation among methicillin-susceptible Staphylococcus aureus (MSSA) isolates collected from a tertiary hospital in Terengganu, Malaysia
Published in International microbiology (01-11-2023)“…Methicillin-susceptible Staphylococcus aureus (MSSA) is an important nosocomial pathogen worldwide. This study aims to investigate the in vitro biofilm-forming…”
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Genetic Polymorphisms of Interleukin-4 Third Intron Region in the Malaysian Patients with Systemic Lupus Erythematosus
Published in Journal of medical sciences (Faisalābād, Pakistan) (15-06-2008)“…In this study, we analysed the genetic polymorphisms present in the third intron region of Interleukin-4 gene in Malaysian patients with Systemic Lupus…”
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Novel mutations in SKIV2L and TTC37 genes in Malaysian children with trichohepatoenteric syndrome
Published in Gene (15-07-2016)“…Trichohepatoenteric syndrome (THES) is a rare autosomal recessive disorder that is classically associated with intractable diarrhea with an onset within the…”
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