Search Results - "Kedziora, Katarzyna M."

Initiation of lamellipodia and ruffles involves cooperation between mDia1 and the Arp2/3 complex by Isogai, Tadamoto, van der Kammen, Rob, Leyton-Puig, Daniela, Kedziora, Katarzyna M, Jalink, Kees, Innocenti, Metello

“…Protrusion of lamellipodia and ruffles requires polymerization of branched actin filaments by the Arp2/3 complex. Although regulation of Arp2/3 complex…”
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Evidence that the human cell cycle is a series of uncoupled, memoryless phases by Chao, Hui Xiao, Fakhreddin, Randy I, Shimerov, Hristo K, Kedziora, Katarzyna M, Kumar, Rashmi J, Perez, Joanna, Limas, Juanita C, Grant, Gavin D, Cook, Jeanette Gowen, Gupta, Gaorav P, Purvis, Jeremy E

“…The cell cycle is canonically described as a series of four consecutive phases: G1, S, G2, and M. In single cells, the duration of each phase varies, but the…”
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The molecular architecture of cell cycle arrest by Stallaert, Wayne, Taylor, Sovanny R, Kedziora, Katarzyna M, Taylor, Colin D, Sobon, Holly K, Young, Catherine L, Limas, Juanita C, Varblow Holloway, Jonah, Johnson, Martha S, Cook, Jeanette Gowen, Purvis, Jeremy E

“…The cellular decision governing the transition between proliferative and arrested states is crucial to the development and function of every tissue. While the…”
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An in vitro platform for quantifying cell cycle phase lengths in primary human intestinal epithelial cells by Cotton, Michael J., Ariel, Pablo, Chen, Kaiwen, Walcott, Vanessa A., Dixit, Michelle, Breau, Keith A., Hinesley, Caroline M., Kedziora, Katarzyna M., Tang, Cynthia Y., Zheng, Anna, Magness, Scott T., Burclaff, Joseph

“…The intestinal epithelium dynamically controls cell cycle, yet no experimental platform exists for directly analyzing cell cycle phases in non-immortalized…”
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The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD by Ghosh, Sayan, Sharma, Ruchi, Bammidi, Sridhar, Koontz, Victoria, Nemani, Mihir, Yazdankhah, Meysam, Kedziora, Katarzyna M., Stolz, Donna Beer, Wallace, Callen T., Yu-Wei, Cheng, Franks, Jonathan, Bose, Devika, Shang, Peng, Ambrosino, Helena M., Dutton, James R., Geng, Zhaohui, Montford, Jair, Ryu, Jiwon, Rajasundaram, Dhivyaa, Hose, Stacey, Sahel, José-Alain, Puertollano, Rosa, Finkel, Toren, Zigler, J. Samuel, Sergeev, Yuri, Watkins, Simon C., Goetzman, Eric S., Ferrington, Deborah A., Flores-Bellver, Miguel, Kaarniranta, Kai, Sodhi, Akrit, Bharti, Kapil, Handa, James T., Sinha, Debasish

“…Non-neovascular or dry age-related macular degeneration (AMD) is a multi-factorial disease with degeneration of the aging retinal-pigmented epithelium (RPE)…”
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Optotaxis: Caged Lysophosphatidic Acid Enables Optical Control of a Chemotactic Gradient by Hövelmann, Felix, Kedziora, Katarzyna M, Nadler, André, Müller, Rainer, Jalink, Kees, Schultz, Carsten

“…Lysophosphatidic acid (LPA) is a serum-borne lipid mediator that binds to a variety of different G protein-coupled receptors to trigger an exceptionally wide…”
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Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome by Matas-Rico, Elisa, van Veen, Michiel, Leyton-Puig, Daniela, van den Berg, Jeroen, Koster, Jan, Kedziora, Katarzyna M., Molenaar, Bas, Weerts, Marjolein J.A., de Rink, Iris, Medema, René H., Giepmans, Ben N.G., Perrakis, Anastassis, Jalink, Kees, Versteeg, Rogier, Moolenaar, Wouter H.

“…Neuroblastoma is a pediatric embryonal malignancy characterized by impaired neuronal differentiation. A better understanding of neuroblastoma differentiation…”
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AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis by Descovich, Carlos P, Lough, Kendall J, Jena, Akankshya, Wu, Jessica J, Yom, Jina, Spitzer, Danielle C, Uppalapati, Manuela, Kedziora, Katarzyna M, Williams, Scott E

“…Oriented cell divisions balance self-renewal and differentiation in stratified epithelia such as the skin epidermis. During peak epidermal stratification, the…”
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Inheritance of OCT4 predetermines fate choice in human embryonic stem cells by Wolff, Samuel C, Kedziora, Katarzyna M, Dumitru, Raluca, Dungee, Cierra D, Zikry, Tarek M, Beltran, Adriana S, Haggerty, Rachel A, Cheng, JrGang, Redick, Margaret A, Purvis, Jeremy E

“…It is well known that clonal cells can make different fate decisions, but it is unclear whether these decisions are determined during, or before, a cell's own…”
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Antibiotic-induced accumulation of lipid II synergizes with antimicrobial fatty acids to eradicate bacterial populations by Sidders, Ashelyn E, Kedziora, Katarzyna M, Arts, Melina, Daniel, Jan-Martin, de Benedetti, Stefania, Beam, Jenna E, Bui, Duyen T, Parsons, Joshua B, Schneider, Tanja, Rowe, Sarah E, Conlon, Brian P

“…Antibiotic tolerance and antibiotic resistance are the two major obstacles to the efficient and reliable treatment of bacterial infections. Identifying…”
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Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells by van Veen, Michiel, Matas-Rico, Elisa, van de Wetering, Koen, Leyton-Puig, Daniela, Kedziora, Katarzyna M, De Lorenzi, Valentina, Stijf-Bultsma, Yvette, van den Broek, Bram, Jalink, Kees, Sidenius, Nicolai, Perrakis, Anastassis, Moolenaar, Wouter H

“…The urokinase receptor (uPAR) is a glycosylphosphatidylinositol (GPI)-anchored protein that promotes tissue remodeling, tumor cell adhesion, migration and…”
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Harnessing ultrasound-stimulated phase change contrast agents to improve antibiotic efficacy against methicillin-resistant Staphylococcus aureus biofilms by Durham, Phillip G., Sidders, Ashelyn E., Beam, Jenna E., Kedziora, Katarzyna M., Dayton, Paul A., Conlon, Brian P., Papadopoulou, Virginie, Rowe, Sarah E.

“…Bacterial biofilms, often associated with chronic infections, respond poorly to antibiotic therapy and frequently require surgical intervention. Biofilms…”
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PFA fixation enables artifact-free super-resolution imaging of the actin cytoskeleton and associated proteins by Leyton-Puig, Daniela, Kedziora, Katarzyna M, Isogai, Tadamoto, van den Broek, Bram, Jalink, Kees, Innocenti, Metello

“…Super-resolution microscopy (SRM) allows precise localization of proteins in cellular organelles and structures, including the actin cytoskeleton. Yet sample…”
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Chemical screen for epigenetic barriers to single allele activation of Oct4 by Headley, Kathryn M., Kedziora, Katarzyna M., Alejo, Aidin, Lai, Elianna Zhi-Xiang, Purvis, Jeremy E., Hathaway, Nathaniel A.

“…Here we utilized the chromatin in vivo assay (CiA) mouse platform to directly examine the epigenetic barriers impeding the activation of the CiA:Oct4 allele in…”
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Method of calibration of a fluorescence microscope for quantitative studies by KEDZIORA, KATARZYNA M., PREHN, JOHEN H.M., DOBRUCKI, JUREK, BERNAS, TYTUS

“…Summary Confocal microscopy is based on measurement of intensity of fluorescence originating from a limited volume in the imaged specimen. The intensity is…”
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Accurate delineation of cell cycle phase transitions in living cells with PIP-FUCCI by Grant, Gavin D., Kedziora, Katarzyna M., Limas, Juanita C., Cook, Jeanette Gowen, Purvis, Jeremy E.

“…Cell cycle phase transitions are tightly orchestrated to ensure efficient cell cycle progression and genome stability. Interrogating these transitions is…”
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The consequences of differential origin licensing dynamics in distinct chromatin environments by Mei, Liu, Kedziora, Katarzyna M, Song, Eun-Ah, Purvis, Jeremy E, Cook, Jeanette Gowen

“…Eukaryotic chromosomes contain regions of varying accessibility, yet DNA replication factors must access all regions. The first replication step is loading MCM…”
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Bistable switches as integrators and actuators during cell cycle progression by Stallaert, Wayne, Kedziora, Katarzyna M., Chao, Hui Xiao, Purvis, Jeremy E.

“…Progression through the cell cycle is driven by bistable switches—specialized molecular circuits that govern transitions from one cellular state to another…”
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Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding by Skrajna, Aleksandra, Goldfarb, Dennis, Kedziora, Katarzyna M, Cousins, Emily M, Grant, Gavin D, Spangler, Cathy J, Barbour, Emily H, Yan, Xiaokang, Hathaway, Nathaniel A, Brown, Nicholas G, Cook, Jeanette G, Major, Michael B, McGinty, Robert K

“…Abstract Nuclear proteins bind chromatin to execute and regulate genome-templated processes. While studies of individual nucleosome interactions have suggested…”
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Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA–mDia2 signaling and filopodium formation by Argenzio, Elisabetta, Klarenbeek, Jeffrey, Kedziora, Katarzyna M., Nahidiazar, Leila, Isogai, Tadamoto, Perrakis, Anastassis, Jalink, Kees, Moolenaar, Wouter H., Innocenti, Metello

“…Chloride intracellular channel 4 (CLIC4) is a cytosolic protein implicated in diverse actin-based processes, including integrin trafficking, cell adhesion, and…”
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