Search Results - "Kedar, I"
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Imaging-based prostate cancer screening among BRCA mutation carriers—results from the first round of screening
Published in Annals of oncology (01-11-2020)“…Male-carriers of BRCA1/2 gene mutations have an increased risk of prostate cancer (PCa) with a more aggressive phenotype. Current screening-guidelines suggest…”
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Common founder BRCA2 pathogenic variants and breast cancer characteristics in Ethiopian Jews
Published in Breast cancer research and treatment (01-05-2022)“…Purpose BRCA1/2 founder pathogenic variants (PVs) occur in various populations, but data on the mutational spectrum in Africans are limited. We examined…”
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Oncotype-DX recurrence score distribution in breast cancer patients with BRCA1/2 mutations
Published in Breast cancer research and treatment (01-06-2016)“…Oncotype-DX assay has never been validated for BRCA mutation carriers. This study compares the recurrence score (RS) distribution in BRCA-positive breast…”
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The gastrointestinal manifestation of constitutional mismatch repair deficiency syndrome: from a single adenoma to polyposis-like phenotype and early onset cancer
Published in Clinical genetics (01-11-2015)“…Data on the clinical presentation of constitutional mismatch repair deficiency syndrome (CMMRD) is accumulating. However, as the extraintestinal manifestations…”
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Genetic features of Lynch syndrome in the Israeli population
Published in Clinical genetics (01-06-2015)“…Diagnosis of Lynch syndrome (LS) may be complex. Knowledge of mutation spectrum and founder mutations in specific populations facilitates the diagnostic…”
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A novel founder MSH2 deletion in Ethiopian Jews is mainly associated with early-onset colorectal cancer
Published in Familial cancer (01-04-2022)“…Lynch syndrome is an inherited cancer predisposition syndrome caused by germline defects in any of the mismatch repair (MMR) genes. Diagnosis of carriers makes…”
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Switching from Tacrolimus to Sirolimus Halts the Appearance of New Sebaceous Neoplasms in Muir‐Torre Syndrome
Published in American journal of transplantation (01-02-2007)“…Little is known about the effects of immunosuppression on patients with hereditary nonpolyposis colorectal cancer (HNPCC). We describe a kidney transplant…”
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Thalidomide reduces serum C‐reactive protein and interleukin‐6 and induces response to IL‐2 in a fraction of metastatic renal cell cancer patients who failed IL‐2‐based therapy
Published in International journal of cancer (10-06-2004)“…Interleukin‐2 (IL‐2) has some antitumor activity in patients with renal cell carcinoma. It has been noted that response to IL‐2 and prognosis may be adversely…”
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Prolonged overall survival of metastatic gastric cancer patients with BRCA germline mutations
Published in Annals of oncology (01-06-2018)Get full text
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Medical records hit the "intranet"
Published in Nature medicine (01-04-1996)Get full text
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A negative second trimester triple test and absence of specific ultrasonographic markers may decrease the need for genetic amniocentesis in advanced maternal age by 60
Published in Prenatal diagnosis (01-01-2002)“…Objective A study was conducted to evaluate the sensitivity of combining a second trimester triple test and targeted ultrasound in order to detect Down…”
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AIDS physicians find support in the trenches
Published in Nature medicine (01-02-1996)Get full text
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LBA22 Imaging based PCa screening among BRCA mutation carriers: Results from the first round of screening
Published in Annals of oncology (01-09-2020)Get full text
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Replication asynchrony increases in women at risk for aneuploid offspring
Published in Chromosome research (01-02-2000)“…We attempted to demonstrate a relation between a loss of replication control, centromere dysfunction, and predisposition to non-disjunction. Couples with a…”
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ARE ALL PHENOTYPICALLY-NORMAL TURNER SYNDROME FETUSES MOSAICS?
Published in Prenatal diagnosis (01-09-1996)“…Cytogenetic and fluorescent in situ hybridization (FISH) studies were performed on several formalin‐fixed tissues obtained from four fetuses diagnosed at…”
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Thermochemotherapy: Synergism between Hyperthermia (42-43 degrees) and Adriamycin (or Bleomycin) in Mammalian Cell Inactivation
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1975)“…The sensitivity of cells exposed in vitro to the antibiotics bleomycin or adriamycin is only mildly increased at 41 degrees over that seen at 37 degrees…”
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Fluorescent in-situ hybridization (FISH) as an aid to marker chromosome identification in prenatal diagnosis
Published in European journal of obstetrics & gynecology and reproductive biology (01-03-1995)“…Five cases of supernumerary marker chromosomes were identified in prenatal diagnosis as derived from chromosomes 18, X, and Y. One unexpected finding was in a…”
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Differential Diagnosis and Management of Very Low Second Trimester Maternal Serum Unconjugated Estriol Levels, With Special Emphasis on the Diagnosis of X-Linked Ichthyosis
Published in Obstetrical & gynecological survey (01-03-1996)“…Incorporation of maternal serum unconjugated estriol into the calculation of risk may increase the yield of serum screening performed during pregnancy for…”
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