Search Results - "Keck, Tobias"

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs by Wellner, Ulrich, Schubert, Jörg, Burk, Ulrike C., Schmalhofer, Otto, Zhu, Feng, Sonntag, Annika, Waldvogel, Bettina, Vannier, Corinne, Darling, Douglas, Hausen, Axel zur, Brunton, Valerie G., Morton, Jennifer, Sansom, Owen, Schüler, Julia, Stemmler, Marc P., Herzberger, Christoph, Hopt, Ulrich, Keck, Tobias, Brabletz, Simone, Brabletz, Thomas

“…The epithelial-to-mesenchymal transition transcription factor ZEB1 is involved in metastasis. It is now shown to regulate the tumour-initiating capacity of…”
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The Lymph Node Ratio is the Strongest Prognostic Factor after Resection of Pancreatic Cancer by Riediger, Hartwig, Keck, Tobias, Wellner, Ulrich, zur Hausen, Axel, Adam, Ulrich, Hopt, Ulrich T., Makowiec, Frank

“…Introduction Survival after surgery of pancreatic cancer is still poor, even after curative resection. Some prognostic factors like the status of the resection…”
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Neoadjuvant chemotherapy with gemcitabine plus cisplatin followed by radical liver resection versus immediate radical liver resection alone with or without adjuvant chemotherapy in incidentally detected gallbladder carcinoma after simple cholecystectomy or in front of radical resection of BTC (ICC/ECC) - a phase III study of the German registry of incidental gallbladder carcinoma platform (GR)- the AIO/ CALGP/ ACO- GAIN-trial by Goetze, Thorsten O, Bechstein, Wolf O, Bankstahl, Ulli Simone, Keck, Tobias, Königsrainer, Alfred, Lang, Sven A, Pauligk, Claudia, Piso, Pompiliu, Vogel, Arndt, Al-Batran, Salah-Eddin

“…Currently, complete surgical resection represents the only potentially curative treatment option for Biliary Tract Cancer (BTC) including Gallbladder Cancer…”
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ZEB1‐associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat by Meidhof, Simone, Brabletz, Simone, Lehmann, Waltraut, Preca, Bogdan‐Tiberius, Mock, Kerstin, Ruh, Manuel, Schüler, Julia, Berthold, Maria, Weber, Anika, Burk, Ulrike, Lübbert, Michael, Puhr, Martin, Culig, Zoran, Wellner, Ulrich, Keck, Tobias, Bronsert, Peter, Küsters, Simon, Hopt, Ulrich T, Stemmler, Marc P, Brabletz, Thomas

“…Therapy resistance is a major clinical problem in cancer medicine and crucial for disease relapse and progression. Therefore, the clinical need to overcome it,…”
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Transatlantic registries of pancreatic surgery in the United States of America, Germany, the Netherlands, and Sweden: Comparing design, variables, patients, treatment strategies, and outcomes by Mackay, Tara. M., Gleeson, Elizabeth M., Wellner, Ulrich F., Williamsson, Caroline, Busch, Olivier R., Groot Koerkamp, Bas, Keck, Tobias, van Santvoort, Hjalmar C., Tingstedt, Bobby, Pitt, Henry A., Besselink, Marc G.

“…Registries of pancreatic surgery have become increasingly popular as they facilitate both quality improvement and clinical research. We aimed to compare…”
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Prognostic significance of Zinc finger E-box binding homeobox 1 (ZEB1) expression in cancer cells and cancer-associated fibroblasts in pancreatic head cancer by Bronsert, Peter, MD, Kohler, Ilona, MD, Timme, Sylvia, MD, Kiefer, Selina, MD, Werner, Martin, MD, Schilling, Oliver, PhD, Vashist, Yogesh, MD, Makowiec, Frank, MD, Brabletz, Thomas, MD, Hopt, Ulrich T., MD, Bausch, Dirk, MD, Kulemann, Birte, MD, Keck, Tobias, MD, MBA, FACS, Wellner, Ulrich F., MD

“…Background Pancreatic ductal adenocarcinoma (PDAC) is characterized by an aggressive biology and poor prognosis. Experimental evidence has suggested a role for…”
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Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial by Diener, Markus K, MD, Seiler, Christoph M, Prof, Rossion, Inga, MD, Kleeff, Jörg, Prof, Glanemann, Matthias, MD, Butturini, Giovanni, MD, Tomazic, Ales, MD, Bruns, Christiane J, Prof, Busch, Olivier RC, Prof, Farkas, Stefan, MD, Belyaev, Orlin, MD, Neoptolemos, John P, Prof, Halloran, Christopher, MD, Keck, Tobias, Prof, Niedergethmann, Marco, Prof, Gellert, Klaus, Prof, Witzigmann, Helmut, Prof, Kollmar, Otto, MD, Langer, Peter, Prof, Steger, Ulrich, MD, Neudecker, Jens, MD, Berrevoet, Frederik, MD, Ganzera, Silke, MD, Heiss, Markus M, Prof, Luntz, Steffen P, MD, Bruckner, Thomas, PhD, Kieser, Meinhard, Prof, Büchler, Markus W, Prof

“…Summary Background The ideal closure technique of the pancreas after distal pancreatectomy is unknown. We postulated that standardised closure with a stapler…”
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Influence of Anastomotic Leak After Elective Colorectal Cancer Resection on Survival and Local Recurrence: A Propensity Score Analysis by Zimmermann, Markus S, Wellner, Ulrich, Laubert, Tilman, Ellebrecht, David B, Bruch, Hans-Peter, Keck, Tobias, Schlöricke, Erik, Benecke, Claudia R

“…BACKGROUND:The occurrence of anastomotic leakage is still a life-threatening complication for patients after colorectal surgery. In literature not only an…”
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Short- and long-term results of duodenum preservation versus resection for the management of chronic pancreatitis: A prospective, randomized study by Keck, Tobias, MD, Adam, Ulrich, MD, Makowiec, Frank, MD, Riediger, Hartwig, MD, Wellner, Ulrich, MD, Tittelbach-Helmrich, Dietlind, MD, Hopt, Ulrich T., MD

“…Background Individualization of operations for chronic pancreatitis (CP) offers tailored operative approaches for the management of complications of CP. For…”
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Alignment of stroma fibers, microvessel density and immune cell populations determine overall survival in pancreatic cancer—An analysis of stromal morphology by Bolm, Louisa, Zghurskyi, Petro, Lapshyn, Hryhoriy, Petrova, Ekaterina, Zemskov, Sergiy, Vashist, Yogesh K, Deichmann, Steffen, Honselmann, Kim C, Bronsert, Peter, Keck, Tobias, Wellner, Ulrich F

“…Introduction The aim of this study was to define histo-morphological stroma characteristics by analyzing stromal components, and to evaluate their impact on…”
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Towards a Holistic Workflow Optimization in the Operating Theater: Exploring Optimal Placements of Robotic Systems by Adiyaman, Cem, Hagenah, Jannis, Kundrat, Dennis, Keck, Tobias, Männel, Georg

“…The level of digitalization and automation, including robotic systems, is increasing in modern operating theaters. However, the integration of such systems…”
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Deep transfer learning methods for colon cancer classification in confocal laser microscopy images by Gessert, Nils, Bengs, Marcel, Wittig, Lukas, Drömann, Daniel, Keck, Tobias, Schlaefer, Alexander, Ellebrecht, David B.

“…Purpose The gold standard for colorectal cancer metastases detection in the peritoneum is histological evaluation of a removed tissue sample. For feedback…”
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Tumor budding as a prognostic factor in pancreatic ductal adenocarcinoma by Petrova, Ekaterina, Zielinski, Verena, Bolm, Louisa, Schreiber, Cleopatra, Knief, Juliana, Thorns, Christoph, Bronsert, Peter, Timme-Bronsert, Sylvia, Bausch, Dirk, Perner, Sven, Keck, Tobias, Wellner, Ulrich

“…In this retrospective study, we analyzed the association between tumor budding and perineural invasion as well as their prognostic role in pancreatic ductal…”
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Randomized Controlled Single-Center Trial Comparing Pancreatogastrostomy Versus Pancreaticojejunostomy After Partial Pancreatoduodenectomy by Wellner, Ulrich F., Sick, Olivia, Olschewski, Manfred, Adam, Ulrich, Hopt, Ulrich T., Keck, Tobias

“…Background The aim of this single-center randomized trial was to compare the perioperative outcome of pancreatoduodenectomy with pancreatogastrostomy (PG) vs…”
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Detailed analysis of epithelial-mesenchymal transition and tumor budding identifies predictors of long-term survival in pancreatic ductal adenocarcinoma by Kohler, Ilona, Bronsert, Peter, Timme, Sylvia, Werner, Martin, Brabletz, Thomas, Hopt, Ulrich Theodor, Schilling, Oliver, Bausch, Dirk, Keck, Tobias, Wellner, Ulrich Friedrich

“…Background and Aim Pancreatic ductal adenocarcinoma (PDAC) is characterized by aggressive biology and poor prognosis even after resection. Long‐term survival…”
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Dietary supplementation with n-3-fatty acids in patients with pancreatic cancer and cachexia: marine phospholipids versus fish oil - a randomized controlled double-blind trial by Werner, Kristin, Küllenberg de Gaudry, Daniela, Taylor, Lenka A, Keck, Tobias, Unger, Clemens, Hopt, Ulrich T, Massing, Ulrich

“…Like many other cancer patients, most pancreatic carcinoma patients suffer from severe weight loss. As shown in numerous studies with fish oil (FO)…”
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A simple scoring system based on clinical factors related to pancreatic texture predicts postoperative pancreatic fistula preoperatively by Wellner, Ulrich Friedrich, Kayser, Gian, Lapshyn, Hryhoriy, Sick, Olivia, Makowiec, Frank, Höppner, Jens, Hopt, Ulrich Theodor, Keck, Tobias

“…Postoperative pancreatic fistula (POPF) is regarded as the most serious complication of pancreatic surgery. The preoperative risk stratification of patients by…”
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The use and clinical outcome of total pancreatectomy in the United States, Germany, the Netherlands, and Sweden by Latenstein, Anouk E.J., Mackay, Tara M., Beane, Joal D., Busch, Olivier R., van Dieren, Susan, Gleeson, Elizabeth M., Koerkamp, Bas Groot, van Santvoort, Hjalmar C., Wellner, Ulrich F., Williamsson, Caroline, Tingstedt, Bobby, Keck, Tobias, Pitt, Henry A., Besselink, Marc G.

“…Total pancreatectomy has high morbidity and mortality and differences among countries are currently unknown. This study compared the use and postoperative…”
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Perioperative and Long-Term Outcome after Standard Pancreaticoduodenectomy, Additional Portal Vein and Multivisceral Resection for Pancreatic Head Cancer by Kulemann, Birte, Hoeppner, Jens, Wittel, Uwe, Glatz, Torben, Keck, Tobias, Wellner, Ulrich F., Bronsert, Peter, Sick, Olivia, Hopt, Ulrich T., Makowiec, Frank, Riediger, Hartwig

“…Introduction The value of extended resection (portal vein, multivisceral) in patients with pancreatic adenocarcinoma (PDAC) is not well defined. We analyzed…”
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Figures do matter: A literature review of 4587 robotic pancreatic resections and their implications on training by Levi Sandri, Giovanni B., Abu Hilal, Mohammed, Dokmak, Safi, Edwin, Bjørn, Hackert, Thilo, Keck, Tobias, Khatkov, Igor, Besselink, Marc G., Boggi, Ugo, Sanchez‐Velazquez, Patricia, Soubrane, Olivier, Vanlander, Aude, Awad Nogoud, Alaeldin, Aldrighetti, Luca, Hoti, Emir

“…Background The use of robotic assistance in minimally invasive pancreatic resection is quickly growing. Methods We present a systematic review of the…”
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