Search Results - "Keaveny, T. M."

Prediction of incident vertebral fracture using CT-based finite element analysis by Allaire, B. T., Lu, D., Johannesdottir, F., Kopperdahl, D., Keaveny, T. M., Jarraya, M., Guermazi, A., Bredella, M. A., Samelson, E. J., Kiel, D. P., Anderson, D. E., Demissie, S., Bouxsein, M. L.

“…Summary Prior studies show vertebral strength from computed tomography-based finite element analysis may be associated with vertebral fracture risk. We found…”
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A biomechanical perspective on bone quality by Hernandez, C.J., Keaveny, T.M.

“…Observations that dual-energy X-ray absorptiometry (DXA) measures of areal bone mineral density cannot completely explain fracture incidence after…”
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Finite element models predict the location of microdamage in cancellous bone following uniaxial loading by Goff, M.G, Lambers, F.M, Sorna, R.M, Keaveny, T.M, Hernandez, C.J

“…Abstract High-resolution finite element models derived from micro-computed tomography images are often used to study the effects of trabecular…”
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BIOMECHANICS OF TRABECULAR BONE by Keaveny, Tony M, Morgan, Elise F, Niebur, Glen L, Yeh, Oscar C

“…Trabecular bone is a complex material with substantial heterogeneity. Its elastic and strength properties vary widely across anatomic sites, and with aging and…”
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Mechanical failure begins preferentially near resorption cavities in human vertebral cancellous bone under compression by Slyfield, C.R, Tkachenko, E.V, Fischer, S.E, Ehlert, K.M, Yi, I.H, Jekir, M.G, O'Brien, R.G, Keaveny, T.M, Hernandez, C.J

“…Abstract The amount of bone turnover in the body has been implicated as a factor that can influence fracture risk and bone strength. Here we test the idea that…”
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Dependence of intertrabecular permeability on flow direction and anatomic site by NAUMAN, E. A, FONG, K. E, KEAVENY, T. M

“…The structure-function relationships for the permeability of trabecular bone may have relevance for tissue engineering, total joint replacements, and whole…”
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Three-dimensional characterization of resorption cavity size and location in human vertebral trabecular bone by Goff, M.G, Slyfield, C.R, Kummari, S.R, Tkachenko, E.V, Fischer, S.E, Yi, Y.H, Jekir, M.G, Keaveny, T.M, Hernandez, C.J

“…Abstract The number and size of resorption cavities in cancellous bone are believed to influence rates of bone loss, local tissue stress and strain and…”
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Biomechanical Computed Tomography analysis (BCT) for clinical assessment of osteoporosis by Keaveny, T.M., Clarke, B.L., Cosman, F., Orwoll, E.S., Siris, E.S., Khosla, S., Bouxsein, M.L.

“…The surgeon general of the USA defines osteoporosis as “a skeletal disorder characterized by compromised bone strength, predisposing to an increased risk of…”
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Convergence behavior of high-resolution finite element models of trabecular bone by Niebur, G L, Yuen, J C, Hsia, A C, Keaveny, T M

“…The convergence behavior of finite element models depends on the size of elements used, the element polynomial order, and on the complexity of the applied…”
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Biomechanical effects of intraspecimen variations in trabecular architecture: a three-dimensional finite element study by Yeh, O.C., Keaveny, T.M.

“…Trabecular architecture is considered important in osteoporosis and has been quantified by a variety of mean parameters characteristic of a whole specimen…”
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Osteoblasts respond to pulsatile fluid flow with short-term increases in PGE2 but no change in mineralization by Nauman, E. A, Satcher, R. L, Keaveny, T. M, Halloran, B. P, Bikle, D. D

“…1  Orthopaedic Biomechanics Laboratory, Department of Mechanical Engineering, University of California, Berkeley 94720-1740; 2  Veterans Affairs Medical…”
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Impact of Spatial Resolution on the Prediction of Trabecular Architecture Parameters by Kothari, M., Keaveny, T.M., Lin, J.C., Newitt, D.C., Genant, H.K., Majumdar, S.

“…Although the efficacy of various measures for the assessment of trabecular bone architecture has been widely studied, the impact of spatial resolution on the…”
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A cellular solid criterion for predicting the axial-shear failure properties of bovine trabecular bone by Fenech, C M, Keaveny, T M

“…In a long-term effort to develop a complete multi-axial failure criterion for human trabecular bone, the overall goal of this study was to compare the ability…”
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Bone density and strength from thoracic and lumbar CT scans both predict incident vertebral fractures independently of fracture location by Johannesdottir, F., Allaire, B., Kopperdahl, D.L., Keaveny, T.M., Sigurdsson, S., Bredella, M.A., Anderson, D.E., Samelson, E.J., Kiel, D.P., Gudnason, V.G., Bouxsein, M.L.

“…Summary In a population-based study, we found that computed tomography (CT)-based bone density and strength measures from the thoracic spine predicted new…”
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Effect of testosterone treatment on the trabecular bone score in older men with low serum testosterone by Cauley, J. A., Ellenberg, S. S., Schwartz, A. V., Ensrud, K. E., Keaveny, T. M., Snyder, P. J.

“…Summary The trabecular bone score (TBS) is an indirect measure of vertebral bone microarchitecture. Our objective was to examine the effect of testosterone…”
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Validity of serial milling-based imaging system for microdamage quantification by Bigley, R.F, Singh, M, Hernandez, C.J, Kazakia, G.J, Martin, R.B, Keaveny, T.M

“…Abstract Understanding the three-dimensional distribution of microdamage within trabecular bone may help provide a better understanding of the mechanisms of…”
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Treatment of bone loss in proximal femurs of postmenopausal osteoporotic women with AGN1 local osteo-enhancement procedure (LOEP) increases hip bone mineral density and hip strength: a long-term prospective cohort study by Howe, J.G., Hill, R.S., Stroncek, J.D., Shaul, J.L., Favell, D., Cheng, R.R., Engelke, K., Genant, H.K., Lee, D.C., Keaveny, T.M., Bouxsein, M.L., Huber, B.

“…Summary This first-in-human study of AGN1 LOEP demonstrated that this minimally-invasive treatment durably increased aBMD in femurs of osteoporotic…”
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Systematic and random errors in compression testing of trabecular bone by Keaveny, T M, Pinilla, T P, Crawford, R P, Kopperdahl, D L, Lou, A

“…We sought to quantify the systematic and random errors associated with end-artifacts in the platens compression test for trabecular bone. Our hypothesis was…”
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Creep contributes to the fatigue behavior of bovine trabecular bone by Bowman, S M, Guo, X E, Cheng, D W, Keaveny, T M, Gibson, L J, Hayes, W C, McMahon, T A

“…Repetitive, low-intensity loading from normal daily activities can generate fatigue damage in trabecular bone, a potential cause of spontaneous fractures of…”
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Mechanical behavior of human trabecular bone after overloading by Keaveny, T M, Wachtel, E F, Kopperdahl, D L

“…With the etiology of osteoporotic fractures as motivation, the goal of this study was to characterize the mechanical behavior of human trabecular bone after…”
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