Search Results - "Keating, D."
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Aqueous Phase Separation as a Possible Route to Compartmentalization of Biological Molecules
Published in Accounts of chemical research (18-12-2012)“…How could the incredible complexity of modern cells evolve from something simple enough to have appeared in a primordial soup? This enduring question has…”
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2
Formation of Multiphase Complex Coacervates and Partitioning of Biomolecules within them
Published in Biomacromolecules (10-02-2020)“…Biological systems employ liquid–liquid phase separation to localize macromolecules and processes. The properties of intracellular condensates that allow for…”
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3
Phosphorylation-mediated RNA/peptide complex coacervation as a model for intracellular liquid organelles
Published in Nature chemistry (01-02-2016)“…Biological cells are highly organized, with numerous subcellular compartments. Phosphorylation has been hypothesized as a means to control the…”
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4
From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways
Published in Molecular psychiatry (01-06-2016)“…The human body hosts an enormous abundance and diversity of microbes, which perform a range of essential and beneficial functions. Our appreciation of the…”
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5
Liquid–liquid phase separation in artificial cells
Published in Interface focus (06-10-2018)“…Liquid–liquid phase separation (LLPS) in biology is a recently appreciated means of intracellular compartmentalization. Because the mechanisms driving phase…”
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Phospholipid Membrane Formation Templated by Coacervate Droplets
Published in Langmuir (31-08-2021)“…We report the formation of coacervate-supported phospholipid membranes by hydrating a dried lipid film in the presence of coacervate droplets…”
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7
Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates
Published in Nature communications (30-01-2019)“…Membraneless compartments, such as complex coacervates, have been hypothesized as plausible prebiotic micro-compartments due to their ability to sequester RNA;…”
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Prebiotically-relevant low polyion multivalency can improve functionality of membraneless compartments
Published in Nature communications (23-11-2020)“…Multivalent polyions can undergo complex coacervation, producing membraneless compartments that accumulate ribozymes and enhance catalysis, and offering a…”
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Polyanion-Assisted Ribozyme Catalysis Inside Complex Coacervates
Published in ACS chemical biology (21-06-2019)“…Owing to their ability to encapsulate biomolecules, complex coacervates formed by associative phase separation of oppositely charged polyelectrolytes have been…”
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Variations in body weight, food intake and body composition after long‐term high‐fat diet feeding in C57BL/6J mice
Published in Obesity (Silver Spring, Md.) (01-10-2014)“…Objective To investigate the variations in body weight, food intake, and body composition of both male and female C57BL/6J mice during a diet‐induced obesity…”
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11
Using self-paced reading in research with heritage speakers: a role for reading skill in the online processing of Spanish verb argument specifications
Published in Frontiers in psychology (03-05-2023)“…Relatively little is known about how heritage speakers process language in real time, despite recent calls for the use of online methods such as self-paced…”
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12
Bioreactor droplets from liposome-stabilized all-aqueous emulsions
Published in Nature communications (20-08-2014)“…Artificial bioreactors are desirable for in vitro biochemical studies and as protocells. A key challenge is maintaining a favourable internal environment while…”
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13
Sensitivity to Violations of Gender Agreement in Native and Nonnative Spanish: An Eye-Movement Investigation
Published in Language learning (01-09-2009)“…This article reports the results of an eye‐tracking experiment that investigated the effects of structural distance on readers' sensitivity to violations of…”
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14
Reliability and Concurrent Validity of Global Physical Activity Questionnaire (GPAQ): A Systematic Review
Published in International journal of environmental research and public health (26-10-2019)“…This study aimed to systematically review previous studies on the reliability and concurrent validity of the Global Physical Activity Questionnaire (GPAQ). A…”
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15
Multiphase Water-in-Oil Emulsion Droplets for Cell-Free Transcription–Translation
Published in Langmuir (27-05-2014)“…The construction of genetically encoded cellular mimics in compartments containing organized synthetic cytosols is desirable for the development of artificial…”
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16
Impact of wet-dry cycling on the phase behavior and compartmentalization properties of complex coacervates
Published in Nature communications (27-10-2020)“…Wet-dry cycling on the early Earth is thought to have facilitated production of molecular building blocks of life, but its impact on self-assembly and…”
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17
Combining Catalytic Microparticles with Droplets Formed by Phase Coexistence: Adsorption and Activity of Natural Clays at the Aqueous/Aqueous Interface
Published in Scientific reports (12-06-2017)“…Natural clay particles have been hypothesized as catalysts on the early Earth, potentially facilitating the formation of early organic (bio) molecules…”
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18
Will reducing sugar-sweetened beverage consumption reduce obesity? Evidence supporting conjecture is strong, but evidence when testing effect is weak
Published in Obesity reviews (01-08-2013)“…Summary We provide arguments to the debate question and update a previous meta‐analysis with recently published studies on effects of sugar‐sweetened beverages…”
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Microenvironments created by liquid-liquid phase transition control the dynamic distribution of bacterial division FtsZ protein
Published in Scientific reports (11-10-2016)“…The influence of membrane-free microcompartments resulting from crowding-induced liquid/liquid phase separation (LLPS) on the dynamic spatial organization of…”
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20
Submicrometer Metallic Barcodes
Published in Science (American Association for the Advancement of Science) (05-10-2001)“…We synthesized multimetal microrods intrinsically encoded with submicrometer stripes. Complex striping patterns are readily prepared by sequential…”
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