Use of the flexible film isolator as a single circuit hypoxic chamber for small animals

Use of the flexible film isolator as a single circuit hypoxic chamber for small animals

PVC isolators are now widely used for housing animals and provide a readily available pretested air-tight chamber (Pendry, 1984; Trexler, 1984). We have adapted a flexible film isolator for use as a hypoxic chamber for small animals. The environment within the chamber can be easily and continuously...

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Bibliographic Details
Published in:Laboratory animals (London) Vol. 19; no. 3; pp. 258 - 261
Main Authors: Winter, R.J.D, Keast, C.G, Butler, P.R.E, Rudd, R.M
Format: Journal Article
Language:English
Published: London, England SAGE Publications 01-07-1985
Subjects:
Animals
Atmosphere Exposure Chambers
Cardiomegaly - veterinary
Environment, Controlled
Hypertension, Pulmonary - veterinary
hypoxia
Hypoxia - physiopathology
Hypoxia - veterinary
isolation
laboratory animals
Polycythemia - veterinary
Rats
Rats, Inbred Strains
Rodent Diseases - physiopathology
small animal rearing
Space life sciences
ANIMALS
LABORATORY
ANOXIA
RESPIRATION
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Summary:PVC isolators are now widely used for housing animals and provide a readily available pretested air-tight chamber (Pendry, 1984; Trexler, 1984). We have adapted a flexible film isolator for use as a hypoxic chamber for small animals. The environment within the chamber can be easily and continuously monitored with indwelling probes, obviating the need for a seperate circuit for gas analysis. This design has been used for long-term studies of chronic hypoxia.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0023-6772
1758-1117
DOI:10.1258/002367785780893610