Search Results - "Kearsley, John"

Anti-MUC1 monoclonal antibody (C595) and docetaxel markedly reduce tumor burden and ascites, and prolong survival in an in vivo ovarian cancer model by Wang, Li, Chen, Hongmin, Pourgholami, Mohammad H, Beretov, Julia, Hao, Jingli, Chao, Hongtu, Perkins, Alan C, Kearsley, John H, Li, Yong

“…MUC1 is associated with cellular transformation and tumorigenicity and is considered as an important tumor-associated antigen (TAA) for cancer therapy. We…”
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Emerging roles of radioresistance in prostate cancer metastasis and radiation therapy by Chang, Lei, Graham, Peter H., Hao, Jingli, Bucci, Joseph, Cozzi, Paul J., Kearsley, John H., Li, Yong

“…Radiation therapy (RT) continues to be one of the most popular treatment options for localized prostate cancer (CaP). Local CaP recurrence after RT is a…”
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Prediction of Local Recurrence, Distant Metastases, and Death After Breast-Conserving Therapy in Early-Stage Invasive Breast Cancer Using a Five-Biomarker Panel by MILLAR, Ewan K. A, GRAHAM, Peter H, NASSER, Elias, KEARSLEY, John H, DELANEY, Geoff, PAPADATOS, George, FOX, Christopher, SUTHERLAND, Robert L, O'TOOLE, Sandra A, MCNEIL, Catriona M, BROWNE, Lois, MOREY, Adrienne L, EGGLETON, Sarah, BERETOV, Julia, THEOCHAROUS, Constantine, CAPP, Anne

“…To determine the clinical utility of intrinsic molecular phenotype after breast-conserving therapy (BCT) with lumpectomy and whole-breast irradiation with or…”
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CD44 variant 6 is associated with prostate cancer metastasis and chemo-/radioresistance by Ni, Jie, Cozzi, Paul J., Hao, Jing L., Beretov, Julia, Chang, Lei, Duan, Wei, Shigdar, Sarah, Delprado, Warick J., Graham, Peter H., Bucci, Joseph, Kearsley, John H., Li, Yong

“…INTRODUCTION Prostate cancer (CaP) is the second leading malignancy in older men in Western countries. The role of CD44 variant 6 (CD44v6) in CaP progression…”
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In vitro and in vivo prostate cancer metastasis and chemoresistance can be modulated by expression of either CD44 or CD147 by Hao, Jingli, Madigan, Michele C, Khatri, Aparajita, Power, Carl A, Hung, Tzong-Tyng, Beretov, Julia, Chang, Lei, Xiao, Weiwei, Cozzi, Paul J, Graham, Peter H, Kearsley, John H, Li, Yong

“…CD44 and CD147 are associated with cancer metastasis and progression. Our purpose in the study was to investigate the effects of down-regulation of CD44 or…”
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Combination therapy with the histone deacetylase inhibitor LBH589 and radiation is an effective regimen for prostate cancer cells by Xiao, Weiwei, Graham, Peter H, Hao, Jingli, Chang, Lei, Ni, Jie, Power, Carl A, Dong, Qihan, Kearsley, John H, Li, Yong

“…Radiation therapy (RT) continues to be one of the most popular treatment options for localized prostate cancer (CaP). The purpose of the study was to…”
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Role of the EpCAM (CD326) in prostate cancer metastasis and progression by Ni, Jie, Cozzi, Paul J., Duan, Wei, Shigdar, Sarah, Graham, Peter H., John, Kearsley H., Li, Yong

“…Despite significant advances in surgery, radiotherapy and chemotherapy to treat prostate cancer (CaP), many patients die of secondary disease (metastases)…”
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Wal's story: reflections on presence by Kearsley, John H

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Cancer stem cells in prostate cancer chemoresistance by Ni, Jie, Cozzi, Paul, Hao, Jingli, Duan, Wei, Graham, Peter, Kearsley, John, Li, Yong

“…There is currently no cure for metastatic castration-resistant prostate cancer (CRPC). Chemoresistance and metastatic disease remain the main causes of…”
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The impact of breast cosmetic and functional outcomes on quality of life: long-term results from the St. George and Wollongong randomized breast boost trial by Hau, Eric, Browne, Lois, Capp, Anne, Delaney, Geoff P., Fox, Christopher, Kearsley, John H., Millar, Ewan, Nasser, Elias H., Papadatos, George, Graham, Peter H.

“…The aims of this study were to evaluate the impact of cosmetic and functional outcomes after breast-conserving surgery (BCS) and radiation on quality of life…”
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Low dose histone deacetylase inhibitor, LBH589, potentiates anticancer effect of docetaxel in epithelial ovarian cancer via PI3K/Akt pathway in vitro by Chao, Hongtu, Wang, Li, Hao, Jingli, Ni, Jie, Chang, Lei, Graham, Peter H, Kearsley, John H, Li, Yong

“…Abstract The purpose of this study was to investigate the effect of combination of LBH589 with docetaxel (DTX) on the growth and survival of epithelial ovarian…”
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Rembrandt, Michelangelo, and Stories of Healing by Kearsley, John H., PhD, FRACP, FRANZCR

“…Abstract Two contemporary patient narratives provide an opportunity to reflect on the role of clinicians in the healing process, as seen in the works of…”
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Clinical pharmacology of isoflavones and its relevance for potential prevention of prostate cancer by De Souza, Paul L, Russell, Pamela J, Kearsley, John H, Howes, Laurence G

“…Isoflavones are phytoestrogens that have pleiotropic effects in a wide variety of cancer cell lines. Many of these biological effects involve key components of…”
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CD44 is a biomarker associated with human prostate cancer radiation sensitivity by Xiao, WeiWei, Graham, Peter H., Power, Carl A., Hao, Jingli, Kearsley, John H., Li, Yong

“…CD44 plays an important role in cancer metastasis, chemotherapy, and radiation resistance. The present study investigated the relationship of CD44 expression…”
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Proteomics for Breast Cancer Urine Biomarkers by Beretov, Julia, Wasinger, Valerie C., Graham, Peter H., Millar, Ewan K., Kearsley, John H., Li, Yong

“…Although the survival of breast cancer (BC) patients has increased over the last two decades due to improved screening programs and postoperative adjuvant…”
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"Tu Souffres, Cela Suffit": the compassionate hospital by Kearsley, John H, Youngson, Robin

“…The authors propose that the characteristics of personal (individual) compassion may be extrapolated to the concept of corporate (organizational) compassion…”
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"It is not a disease we treat, but a person": medical students' reflections on their first rotations to an oncology and palliative care unit by Kearsley, John H, Lobb, Elizabeth A

“…Although CST is now widely offered, one aspect of it that appears to be underemphasized is that it affords students the opportunity for personal and…”
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A preliminary study to develop an intervention to facilitate communication between couples in advanced cancer by Mowll, Jane, Lobb, Elizabeth A, Lane, Lisbeth, Lacey, Judith, Chochinov, Harvey M, Kelly, Brian, Agar, Meera, Links, Matthew, Kearsley, John H

“…Psychosocial interventions directed to couples where one has advanced cancer can reduce distress, enhance communication, and provide an opportunity for…”
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Tear Fluid Protein Biomarkers by You, Jingjing, Willcox, Mark D., Madigan, Michele C., Wasinger, Valerie, Schiller, Belinda, Walsh, Bradley J., Graham, Peter H., Kearsley, John H., Li, Yong

“…The tear film covers and protects the ocular surface. It contains various molecules including a large variety of proteins. The protein composition of the tear…”
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'Workshops in healing' for senior medical students: a 5-year overview and appraisal by Kearsley, John H, Lobb, Elizabeth A

“…We report upon the design, content and feedback from an interactive, experiential series of Workshops in Healing for senior medical students. Fifty-six final…”
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