Search Results - "Keane, Margaret G"

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    A Review of the Diagnosis and Management of Premalignant Pancreatic Cystic Lesions by Keane, Margaret G, Afghani, Elham

    Published in Journal of clinical medicine (19-03-2021)
    “…Pancreatic cystic lesions are an increasingly common clinical finding. They represent a heterogeneous group of lesions that include two of the three known…”
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    Systematic review of novel ablative methods in locally advanced pancreatic cancer by Keane, Margaret G, Bramis, Konstantinos, Pereira, Stephen P, Fusai, Giuseppe K

    Published in World journal of gastroenterology : WJG (07-03-2014)
    “…Unresectable locally advanced pancreatic cancer with or without metastatic disease is associated with a very poor prognosis.Current standard therapy is limited…”
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    Excess diabetes mellitus-related deaths during the COVID-19 pandemic in the United States by Lv, Fan, Gao, Xu, Huang, Amy Huaishiuan, Zu, Jian, He, Xinyuan, Sun, Xiaodan, Liu, Jinli, Gao, Ning, Jiao, Yang, Keane, Margaret G., Zhang, Lei, Yeo, Yee Hui, Wang, Youfa, Ji, Fanpu

    Published in EClinicalMedicine (01-12-2022)
    “…Diabetes mellitus (DM) is a critical risk factor for severe SARS-CoV-2 infection, and SARS-CoV-2 infection contributes to worsening glycemic control. The…”
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    Paediatric pancreaticobiliary endoscopy: a 21-year experience from a tertiary hepatobiliary centre and systematic literature review by Keane, Margaret G, Kumar, Mayur, Cieplik, Natascha, Thorburn, Douglas, Johnson, Gavin J, Webster, George J, Chapman, Michael H, Lindley, Keith J, Pereira, Stephen P

    Published in BMC pediatrics (09-02-2018)
    “…In adults ERCP and endoscopic ultrasound (EUS) are standard methods of evaluating and treating many hepatopancreaticobiliary (HPB) conditions. HPB disease is…”
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    Cdc7 is a potent anti-cancer target in pancreatic cancer due to abrogation of the DNA origin activation checkpoint by Huggett, Matthew T, Tudzarova, Slavica, Proctor, Ian, Loddo, Marco, Keane, Margaret G, Stoeber, Kai, Williams, Gareth H, Pereira, Stephen P

    Published in Oncotarget (05-04-2016)
    “…Cdc7 is a serine/threonine kinase which is responsible for the 'firing' of replication origins leading to initiation of DNA replication. Inhibition or…”
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    Sociodemographic trends in the incidence of pancreatic and biliary tract cancer in UK primary care by Keane, Margaret G, Horsfall, Laura J, Rait, Greta, Pereira, Stephen P

    Published in PloS one (30-09-2014)
    “…The UK incidence of pancreatic ductal adenocarcinoma (PDAC) is approximately 9/100,000 population compared with 1-2/100,000 for biliary tract cancer (BTC)…”
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    A prospective trial of CONfocal endomicroscopy in CYSTic lesions of the pancreas: CONCYST-01 by Keane, Margaret G., Wehnert, Natascha, Perez-Machado, Miguel, Fusai, Giuseppe K., Thorburn, Douglas, Oppong, Kofi W., Carroll, Nicholas, Metz, Andrew J., Pereira, Stephen P.

    Published in Endoscopy International Open (01-09-2019)
    “…Abstract Background and study aims Pancreatic cystic lesions (PCL) are common. While some harbor malignant potential, accurate preoperative diagnosis remains…”
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    Novel biomarkers and endoscopic techniques for diagnosing pancreaticobiliary malignancy [version 1; peer review: 2 approved] by Keane, Margaret G, Shah, Amar, Pereira, Stephen P, Joshi, Deepak

    Published in F1000 research (2017)
    “…The UK incidence of pancreatic ductal adenocarcinoma is 9 per 100,000 population, and biliary tract cancer occurs at a rate of 1-2 per 100,000. The incidence…”
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    Clinical and radiological features that predict malignant transformation in cystic lesions of the pancreas: a retrospective case note review by Keane, Margaret G, Dadds, Hannah R, El Sayed, Ghassan, Luong, Tu Vinh, Davidson, Brian R, Fusai, Guiseppe K, Thorburn, Douglas, Pereira, Stephen P

    Published in AMRC open research (16-01-2020)
    “…Pancreatic cystic lesions (PCL) are being detected with increasing frequency. Current methods of stratifying risk of malignant transformation are imperfect…”
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    Early detection of pancreatic cancer by Pereira, Stephen P, Oldfield, Lucy, Ney, Alexander, Hart, Phil A, Keane, Margaret G, Pandol, Stephen J, Li, Debiao, Greenhalf, William, Jeon, Christie Y, Koay, Eugene J, Almario, Christopher V, Halloran, Christopher, Lennon, Anne Marie, Costello, Eithne

    Published in The lancet. Gastroenterology & hepatology (01-07-2020)
    “…Pancreatic ductal adenocarcinoma is most frequently detected at an advanced stage. Such late detection restricts treatment options and contributes to a dismal…”
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    Suturing a 20-mm lumen-apposing metal stent allows for safe same-session EUS-directed transgastric intervention in patients with Roux-en-Y gastric bypass anatomy: a multicenter study (with video) by Keane, Margaret G., Higa, Jennifer T., La Selva, Danielle, Khashab, Mouen A., Irani, Shayan S.

    Published in Gastrointestinal endoscopy (01-02-2023)
    “…EUS-directed transgastric intervention (EDGI) is an established technique for the management of pancreaticobiliary pathology in Roux-en-Y gastric bypass (RYGB)…”
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