Search Results - "Ke, Youqiang"
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The cancer-promoting gene fatty acid-binding protein 5 (FABP5) is epigenetically regulated during human prostate carcinogenesis
Published in Biochemical journal (15-02-2016)“…FABPs (fatty-acid-binding proteins) are a family of low-molecular-mass intracellular lipid-binding proteins consisting of ten isoforms. FABPs are involved in…”
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High expression of Fatty Acid‐Binding Protein 5 promotes cell growth and metastatic potential of colorectal cancer cells
Published in FEBS open bio (01-03-2016)“…Fatty acid‐binding proteins (FABPs) are responsible for binding and storing hydrophobic ligands such as long‐chain fatty acids, and for transporting these…”
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Increased Id-1 expression is significantly associated with poor survival of patients with prostate cancer
Published in Human pathology (01-09-2007)“…Summary The levels of Id-1 (inhibitor of DNA binding or inhibitor of cell differentiation) expression in a series of prostate cell lines and in an archival set…”
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siRNA knockdown of ribosomal protein gene RPL19 abrogates the aggressive phenotype of human prostate cancer
Published in PloS one (22-07-2011)“…We provide novel functional data that posttranscriptional silencing of gene RPL19 using RNAi not only abrogates the malignant phenotype of PC-3M prostate…”
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Letter to the Editor: Perspectives on mRNA Vaccine Development for Cancer
Published in Journal of interferon & cytokine research (01-11-2022)“…Recently, messenger ribonucleic acid (mRNA) vaccine research and development became a hotspot in the field of prevention and treatment of Corona Virus Disease…”
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Heat shock protein expression independently predicts clinical outcome in prostate cancer
Published in Cancer research (Chicago, Ill.) (15-12-2000)“…Heat shock proteins (hsps) occupy a central role in the regulation of intracellular homeostasis, and differential expression of individual hsps occurs in a…”
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Prognostic significance of osteopontin expression in human prostate cancer
Published in International journal of cancer (01-05-2006)“…To test the hypothesis that expression of osteopontin (OPN), an integrin‐binding glycoprotein, can independently predict the potential aggressiveness of…”
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Increased Expression of Id Family Proteins in Small Cell Lung Cancer and its Prognostic Significance
Published in Clinical cancer research (15-04-2008)“…Purpose: To study the molecular pathology of human small cell lung cancer (SCLC), molecular biology approaches were used to identify genes involved in…”
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High-level expression of cutaneous fatty acid-binding protein in prostatic carcinomas and its effect on tumorigenicity
Published in Oncogene (08-05-2003)“…The expression of cutaneous fatty acid-binding protein (C-FABP) in prostate tissues was examined by immunohistochemistry. Among the 76 cases, all seven (100%)…”
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Expression of cutaneous fatty acid-binding protein (C-FABP) in prostate cancer : Potential prognostic marker and target for tumourigenicity-suppression
Published in International journal of oncology (01-04-2008)“…C-FABP or E-FABP is a metastasis inducing gene over expressed in human prostate carcinomas. To study its prognostic significance, an archival set of prostate…”
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Atelocollagen-delivered siRNA targeting the FABP5 gene as an experimental therapy for prostate cancer in mouse xenografts
Published in International journal of oncology (2010)“…The gene FABP5 encodes cutaneous fatty acid binding protein (C-FABP) that is up-regulated in prostate cancer where it acts as a putative oncogene. To test the…”
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Suppressing tumourigenicity of prostate cancer cells by inhibiting osteopontin expression
Published in International journal of oncology (01-04-2011)“…Expression of osteopontin (OPN) is increased in prostate cancer cells. The possibility of utilising the increased OPN as a target to suppress the…”
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Inhibition of tumourigenicity of small cell lung cancer cells by suppressing Id3 expression
Published in International journal of oncology (01-09-2010)“…Id3 is over-expressed in small cell lung cancer (SCLC). To test whether the tumourigenicity of SCLC cells can be inhibited by suppressing Id3 expression, we…”
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Tazarotene-Induced Gene 1 (TIG1) Expression in Prostate Carcinomas and Its Relationship to Tumorigenicity
Published in JNCI : Journal of the National Cancer Institute (03-04-2002)“…Background: Prostate cancer is the most common noncutaneous male cancer and one of the least understood malignant diseases. Identifying key genetic factors…”
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Tissue microarray of head and neck squamous carcinoma : validation of the methodology for the study of cutaneous fatty acid-binding protein, vascular endothelial growth factor, involucrin and Ki-67
Published in Virchows Archiv : an international journal of pathology (01-10-2005)“…Tissue microarrays allow the simultaneous analysis of many tumours using small-diameter cores sampled from larger blocks of tissue, but may be limited by…”
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Primer: tissue fixation and preservation for optimal molecular analysis of urologic tissues
Published in Nature clinical practice urology (01-05-2006)“…Appreciation of the different methods of tissue handling is a prerequisite to obtaining accurate and biologically relevant tissue-based information. When a…”
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Identification of the messenger RNA for human cutaneous fatty acid-binding protein as a metastasis inducer
Published in Cancer research (Chicago, Ill.) (01-05-2000)“…Using our recently developed systematic differential display and complete comparison of gene expression approaches combined with other methods, we have…”
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Human cutaneous fatty acid-binding protein induces metastasis by up-regulating the expression of vascular endothelial growth factor gene in rat Rama 37 model cells
Published in Cancer research (Chicago, Ill.) (01-06-2001)“…Human cutaneous fatty acid-binding protein (C-FABP) gene is capable of inducing the metastatic phenotype when overexpressed in nonmetastatic rat Rama 37 cells…”
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SBFI26 induces triple‐negative breast cancer cells ferroptosis via lipid peroxidation
Published in Journal of cellular and molecular medicine (01-04-2024)“…SBFI26, an inhibitor of FABP5, has been shown to suppress the proliferation and metastasis of tumour cells. However, the underlying mechanism by which SBFI26…”
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Molecular mechanisms on how FABP5 inhibitors promote apoptosis‐induction sensitivity of prostate cancer cells
Published in Cell biology international (01-05-2023)“…Previous work showed that FABP5 inhibitors suppressed the malignant progression of prostate cancer cells, and this suppression might be achieved partially by…”
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