Search Results - "Ke, Yi‐Ci"
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Mild Chronic Colitis Triggers Parkinsonism in LRRK2 Mutant Mice Through Activating TNF‐α Pathway
Published in Movement disorders (01-04-2022)“…Background Leucine‐rich repeat kinase 2 (LRRK2) is a common risk gene for Parkinson's disease (PD) and inflammatory bowel disorders. However, the penetrance of…”
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Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson's disease
Published in eLife (15-11-2021)“…The most frequent missense mutations in familial Parkinson's disease (PD) occur in the highly conserved gene with G2019S mutation. We previously established a…”
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Reply to: Mild Chronic Colitis Triggers Parkinsonism in LRRK2 Mutant Mice through Activating TNF‐α Pathway
Published in Movement disorders (01-03-2022)Get full text
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Early Dysbiosis and Dampened Gut Microbe Oscillation Precede Motor Dysfunction and Neuropathology in Animal Models of Parkinson's Disease
Published in Journal of Parkinson's disease (01-01-2022)“…Studies have shown different gut microbiomes in patients with Parkinson's disease (PD) compared to unaffected controls. However, when the gut microbiota shift…”
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Structure-Activity Relationship of Synthetic 2-Phenylnaphthalenes with Hydroxyl Groups that Inhibit Proliferation and Induce Apoptosis of MCF-7 Cancer Cells
Published in PloS one (22-10-2015)“…In this study, six 2-phenylnaphthalenes with hydroxyl groups were synthesized in high yields by the demethylation of the corresponding…”
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Mitochondrial UQCRC1 mutations cause autosomal dominant parkinsonism with polyneuropathy
Published in Brain (London, England : 1878) (05-12-2020)“…Parkinson's disease is a neurodegenerative disorder with a multifactorial aetiology. Nevertheless, the genetic predisposition in many families with…”
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ATM-mediated co-chaperone DNAJB11 phosphorylation facilitates α-synuclein folding upon DNA double-stranded breaks
Published in NAR Molecular Medicine (18-04-2024)“…Abstract Parkinson's disease (PD) is a prevalent neurodegenerative disorder marked by the pathological accumulation of α-synuclein aggregates in dopaminergic…”
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