Search Results - "Ke, Qiong"
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Ill‐fitting prosthesis is associated with an increased risk of elevated blood pressures
Published in Journal of oral rehabilitation (01-07-2024)“…Objective Previous studies focused on the benefits of adequate prosthodontic treatment, while few studies have investigated the prosthodontic‐related risks to…”
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2
The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy
Published in Nature medicine (01-10-2016)“…The lncRNA Chaer controls hypertrophic heart growth by binding to and interfering with the function of the epigenetic regulator PRC2. Epigenetic reprogramming…”
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3
The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling
Published in Nature communications (01-06-2016)“…Tumour necrosis factor receptor-associated factor 6 (TRAF6) is a ubiquitin E3 ligase that regulates important biological processes. However, the role of TRAF6…”
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Hepatic Interferon Regulatory Factor 6 Alleviates Liver Steatosis and Metabolic Disorder by Transcriptionally Suppressing Peroxisome Proliferator‐Activated Receptor γ in Mice
Published in Hepatology (Baltimore, Md.) (01-06-2019)“…Nonalcoholic fatty liver disease (NAFLD) has become a worldwide epidemic. A large and growing unmet therapeutic need has inspired numerous studies in the…”
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Nek6 knockdown polarized macrophages into a pro-inflammatory phenotype via inhibiting STAT3 expression
Published in International journal of experimental pathology (01-10-2023)“…Recently macrophage polarization has emerged as playing an essential role in the oathogenesis of atherosclerosis, which is the most important underlying…”
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Metformin Is Associated with Higher Incidence of Acidosis, but Not Mortality, in Individuals with COVID-19 and Pre-existing Type 2 Diabetes
Published in Cell metabolism (06-10-2020)“…The safety and efficacy of anti-diabetic drugs are critical for maximizing the beneficial impacts of well-controlled blood glucose on the prognosis of…”
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The E3 Ligase TRIM16 Is a Key Suppressor of Pathological Cardiac Hypertrophy
Published in Circulation research (13-05-2022)“…Pathological cardiac hypertrophy is one of the leading causes of heart failure with highly complicated pathogeneses. The E3 ligase TRIM16 (tripartite…”
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Cell adhesion-mediated mitochondria transfer contributes to mesenchymal stem cell-induced chemoresistance on T cell acute lymphoblastic leukemia cells
Published in Journal of hematology and oncology (22-01-2018)“…Despite the high cure rate of T cell acute lymphoblastic leukemia (T-ALL), drug resistance to chemotherapy remains a significant clinical problem. Bone marrow…”
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TRAF Family Member 4 Promotes Cardiac Hypertrophy Through the Activation of the AKT Pathway
Published in Journal of the American Heart Association (05-09-2023)“…Background Pathological cardiac hypertrophy is a major cause of heart failure morbidity. The complex mechanism of intermolecular interactions underlying the…”
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10
Nestin regulates cellular redox homeostasis in lung cancer through the Keap1–Nrf2 feedback loop
Published in Nature communications (06-11-2019)“…Abnormal cancer antioxidant capacity is considered as a potential mechanism of tumor malignancy. Modulation of oxidative stress status is emerging as an…”
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11
Transplantation of hPSC-derived pericyte-like cells promotes functional recovery in ischemic stroke mice
Published in Nature communications (15-10-2020)“…Pericytes play essential roles in blood–brain barrier (BBB) integrity and dysfunction or degeneration of pericytes is implicated in a set of neurological…”
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Non-contact assessment of cardiac physiology using FO-MVSS-based ballistocardiography: a promising approach for heart failure evaluation
Published in Scientific reports (08-02-2024)“…Continuous monitoring of cardiac motions has been expected to provide essential cardiac physiology information on cardiovascular functioning. A fiber-optic…”
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13
Energy substrate metabolism and oxidative stress in metabolic cardiomyopathy
Published in Journal of molecular medicine (Berlin, Germany) (01-12-2022)“…Metabolic cardiomyopathy is an emerging cause of heart failure in patients with obesity, insulin resistance, and diabetes. It is characterized by impaired…”
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14
NULP1 Alleviates Cardiac Hypertrophy by Suppressing NFAT3 Transcriptional Activity
Published in Journal of the American Heart Association (18-08-2020)“…Background The development of pathological cardiac hypertrophy involves the coordination of a series of transcription activators and repressors, while their…”
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15
Tripartite Motif 8 Contributes to Pathological Cardiac Hypertrophy Through Enhancing Transforming Growth Factor β–Activated Kinase 1–Dependent Signaling Pathways
Published in Hypertension (Dallas, Tex. 1979) (01-02-2017)“…Tripartite motif (TRIM) 8 functions as an E3 ubiquitin ligase, interacting with and ubiquitinating diverse substrates, and is implicated in various…”
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Restoration of Circulating MFGE8 (Milk Fat Globule-EGF Factor 8) Attenuates Cardiac Hypertrophy Through Inhibition of Akt Pathway
Published in Hypertension (Dallas, Tex. 1979) (01-10-2017)“…Cardiac hypertrophy occurs in response to numerous stimuli like neurohumoral stress, pressure overload, infection, and injury, and leads to heart failure…”
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17
Lipoprotein(a) distribution and its association with carotid arteriopathy in the Chinese population
Published in Atherosclerosis (01-05-2023)“…The distribution of lipoprotein(a) [Lp(a)] has not been well-studied in a large population in China. The relationship between Lp(a) and carotid atherosclerosis…”
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Tumor Necrosis Factor Receptor–Associated Factor 3 Is a Positive Regulator of Pathological Cardiac Hypertrophy
Published in Hypertension (Dallas, Tex. 1979) (01-08-2015)“…Cardiac hypertrophy, a common early symptom of heart failure, is regulated by numerous signaling pathways. Here, we identified tumor necrosis factor…”
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19
Targeted ablation of the left middle cervical ganglion prevents ventricular arrhythmias and cardiac injury induced by AMI
Published in Basic research in cardiology (01-02-2024)“…Cardiac sympathetic overactivation is a critical driver in the progression of acute myocardial infarction (AMI). The left middle cervical ganglion (LMCG) is an…”
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20
The prevalence of MAFLD and its association with atrial fibrillation in a nationwide health check-up population in China
Published in Frontiers in endocrinology (Lausanne) (27-09-2022)“…Background and aims The epidemiological characteristics of MAFLD and its relationship with atrial fibrillation (AF) are limited in China. Therefore, we…”
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