Search Results - "Ke, Juntao"
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Genetic variants in m6A modification genes are associated with esophageal squamous-cell carcinoma in the Chinese population
Published in Carcinogenesis (New York) (10-07-2020)“…N 6 -methyladenosine (m 6 A) is an abundant modification in RNAs that affects RNA metabolism, and it is reported to be closely related to cancer occurrence and…”
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CancerSplicingQTL: a database for genome-wide identification of splicing QTLs in human cancer
Published in Nucleic acids research (08-01-2019)“…Abstract Alternative splicing (AS) is a widespread process that increases structural transcript variation and proteome diversity. Aberrant splicing patterns…”
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Systematic Functional Interrogation of Genes in GWAS Loci Identified ATF1 as a Key Driver in Colorectal Cancer Modulated by a Promoter-Enhancer Interaction
Published in American journal of human genetics (03-07-2019)“…Genome-wide association studies (GWASs) have identified approximately 100 colorectal cancer (CRC) risk loci. However, the causal genes in these loci have not…”
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Integrative expression quantitative trait locus–based analysis of colorectal cancer identified a functional polymorphism regulating SLC22A5 expression
Published in European journal of cancer (1990) (01-04-2018)“…Multiple single nucleotide polymorphisms (SNPs) have been found to be highly correlated with colorectal cancer (CRC) risk. However, the variants identified…”
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5
Microbial community structure and shift pattern of industry brine after a long-term static storage in closed tank
Published in Frontiers in microbiology (02-09-2022)“…Brine from Dingyuan Salt Mine (Anhui, China), an athalassohaline hypersaline environment formed in the early tertiary Oligocene, is used to produce table salt…”
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Biodegradation of phthalic acid esters (PAEs) by Janthinobacterium sp. strain E1 under stress conditions
Published in Journal of general and applied microbiology (01-01-2024)“…Phthalates esters (PAEs) are a kind of polymeric material additives widely been added into plastics to improve products’ flexibility. It can easily cause…”
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LINC01149 variant modulates MICA expression that facilitates hepatitis B virus spontaneous recovery but increases hepatocellular carcinoma risk
Published in Oncogene (01-02-2020)“…Interpreting disease-causing variants, especially in noncoding regions by genome-wide association studies (GWAS), has become one of the most challenging and…”
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A Rare Variant P507L in TPP1 Interrupts TPP1-TIN2 Interaction, Influences Telomere Length, and Confers Colorectal Cancer Risk in Chinese Population
Published in Cancer epidemiology, biomarkers & prevention (01-09-2018)“…Telomere dysfunction triggers cellular senescence and constitutes a driving force for cancer initiation. Genetic variants in genes involved in telomere…”
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Expression, purification, and enzymatic characterization of an extracellular protease from Halococcus salifodinae
Published in Brazilian journal of microbiology (01-12-2023)“…Extracellular proteases from halophilic archaea displays increased enzymatic activities in hypersaline environment. In this study, an extracellular…”
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Reelin gene variants and risk of autism spectrum disorders: An integrated meta-analysis
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01-03-2014)“…Autism spectrum disorder (ASD) is a severe neurological disorder with a high degree of heritability. Reelin gene (RELN), which plays a crucial role in the…”
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Evaluation on the Performance of Hydraulic Bitumen Binders under High and Low Temperatures for Pumped Storage Power Station Projects
Published in Materials (03-03-2022)“…The high and low-temperature performance of five hydraulic bitumen binders was evaluated using the dynamic shear rheometer (DSR) test, infrared spectrum test…”
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Exome-wide analysis identifies three low-frequency missense variants associated with pancreatic cancer risk in Chinese populations
Published in Nature communications (11-09-2018)“…Germline coding variants have not been systematically investigated for pancreatic ductal adenocarcinoma (PDAC). Here we report an exome-wide investigation…”
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Non-linear dose–response relationship between cigarette smoking and pancreatic cancer risk: Evidence from a meta-analysis of 42 observational studies
Published in European journal of cancer (1990) (01-01-2014)“…Abstract Background Question remains about the shape of the dose–response relationship between cigarette smoking and pancreatic cancer risk. Methods Relevant…”
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Starvation Affects the Muscular Morphology, Antioxidant Enzyme Activity, Expression of Lipid Metabolism-Related Genes, and Transcriptomic Profile of Javelin Goby (Synechogobius hasta)
Published in Aquaculture nutrition (2022)“…Fish in natural and cultivated environments can be challenged by starvation. However, inducing starvation in a controlled manner cannot only reduce feed…”
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Prevalence and associated risk factors of dyslexic children in a middle-sized city of China: a cross-sectional study
Published in PloS one (15-02-2013)“…There are many discussions about dyslexia based on studies conducted in western countries, and some risk factors to dyslexia, such as gender and home literacy…”
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Three functional variants were identified to affect RPS24 expression and significantly associated with risk of colorectal cancer
Published in Archives of toxicology (2020)“…GWAS-identified 10q22.3 loci with lead SNP rs704017 are significantly associated with CRC risk in both Asian and European populations. However, the functional…”
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Dietary mushroom intake may reduce the risk of breast cancer: evidence from a meta-analysis of observational studies
Published in PloS one (01-04-2014)“…Epidemiological studies have investigated the potential anticancer effects of mushroom intake. This review aims to clarify the evidence on the association of…”
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A genetic variant rs1801274 in FCGR2A as a potential risk marker for Kawasaki disease: a case-control study and meta-analysis
Published in PloS one (05-08-2014)“…Recent genome-wide association study found rs1801274, a functional single nucleotide polymorphism (SNP) in IgG receptor gene FCGR2A, was associated with…”
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Genetic variant in MTRR, but not MTR, is associated with risk of congenital heart disease: an integrated meta-analysis
Published in PloS one (04-03-2014)“…Congenital heart disease (CHD) is one of the most common birth defects and the leading cause of deaths among individuals with congenital structural…”
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The SLC4A7 variant rs4973768 is associated with breast cancer risk: evidence from a case–control study and a meta-analysis
Published in Breast cancer research and treatment (01-12-2012)“…Recent genome-wide association study has identified a genetic variant rs4973768, located in 3′-UTR of solute carrier family 4, sodium bicarbonate…”
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