Search Results - "Ke, Aiwu"

Tumor associated macrophages-derived exosomes facilitate hepatocellular carcinoma malignance by transferring lncMMPA to tumor cells and activating glycolysis pathway by Xu, Minghao, Zhou, Chenhao, Weng, Jialei, Chen, Zhaoshuo, Zhou, Qiang, Gao, Jian, Shi, Guoming, Ke, Aiwu, Ren, Ning, Sun, Huichuan, Shen, Yinghao

“…Abstract Background Tumor-associated macrophages (TAMs), which form a large part of the tumor microenvironment, are normally regulated by metabolic…”
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Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarcinoma by Song, Guohe, Shi, Yang, Meng, Lu, Ma, Jiaqiang, Huang, Siyuan, Zhang, Juan, Wu, Yingcheng, Li, Jiaxin, Lin, Youpei, Yang, Shuaixi, Rao, Dongning, Cheng, Yifei, Lin, Jian, Ji, Shuyi, Liu, Yuming, Jiang, Shan, Wang, Xiaoliang, Zhang, Shu, Ke, Aiwu, Wang, Xiaoying, Cao, Ya, Ji, Yuan, Zhou, Jian, Fan, Jia, Zhang, Xiaoming, Xi, Ruibin, Gao, Qiang

“…Intrahepatic cholangiocarcinoma (iCCA) is a highly heterogeneous cancer with limited understanding of its classification and tumor microenvironment. Here, by…”
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Global immune characterization of HBV/HCV-related hepatocellular carcinoma identifies macrophage and T-cell subsets associated with disease progression by Song, Guohe, Shi, Yang, Zhang, Meiying, Goswami, Shyamal, Afridi, Saifullah, Meng, Lu, Ma, Jiaqiang, Chen, Yi, Lin, Youpei, Zhang, Juan, Liu, Yuming, Jin, Zijie, Yang, Shuaixi, Rao, Dongning, Zhang, Shu, Ke, Aiwu, Wang, Xiaoying, Cao, Ya, Zhou, Jian, Fan, Jia, Zhang, Xiaoming, Xi, Ruibin, Gao, Qiang

“…Diverse immune cells in the tumor microenvironment form a complex ecosystem, but our knowledge of their heterogeneity and dynamics within hepatocellular…”
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Identification of Fasudil as a collaborator to promote the anti-tumor effect of lenvatinib in hepatocellular carcinoma by inhibiting GLI2-mediated hedgehog signaling pathway by Huang, Yilan, Wang, Siwei, Zhang, Xiaojun, Yang, Chen, Wang, Sikai, Cheng, Hongxia, Ke, Aiwu, Gao, Chao, Guo, Kun

“…Lenvatinib is a frontline tyrosine kinase inhibitor for patients with advanced hepatocellular carcinoma (HCC). However, just 25% of patients benefit from the…”
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Intratumor microbiome features reveal antitumor potentials of intrahepatic cholangiocarcinoma by Chai, Xiaoqiang, Wang, Jie, Li, Huanping, Gao, Chao, Li, Shuangqi, Wei, Chuanyuan, Huang, Jianhang, Tian, Yingming, Yuan, Jian, Lu, Jiacheng, Gao, Dongmei, Zheng, Yimin, Huang, Cheng, Zhou, Jian, Shi, Guoming, Ke, Aiwu, Liu, Feng, Fan, Jia, Cai, Jiabin

“…Intrahepatic cholangiocarcinoma (ICC) is a rare malignancy with a high prevalence in China. This study aimed to characterize the ICC tissues' bacterial…”
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Publisher Correction: Single-cell transcriptomic analysis suggests two molecularly distinct subtypes of intrahepatic cholangiocarcinoma by Song, Guohe, Shi, Yang, Meng, Lu, Ma, Jiaqiang, Huang, Siyuan, Zhang, Juan, Wu, Yingcheng, Li, Jiaxin, Lin, Youpei, Yang, Shuaixi, Rao, Dongning, Cheng, Yifei, Lin, Jian, Ji, Shuyi, Liu, Yuming, Jiang, Shan, Wang, Xiaoliang, Zhang, Shu, Ke, Aiwu, Wang, Xiaoying, Cao, Ya, Ji, Yuan, Zhou, Jian, Fan, Jia, Zhang, Xiaoming, Xi, Ruibin, Gao, Qiang

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PGAM1 Inhibition Promotes HCC Ferroptosis and Synergizes with Anti‐PD‐1 Immunotherapy by Zheng, Yimin, Wang, Yining, Lu, Zhou, Wan, Jinkai, Jiang, Lulu, Song, Danjun, Wei, Chuanyuan, Gao, Chao, Shi, Guoming, Zhou, Jian, Fan, Jia, Ke, Aiwu, Zhou, Lu, Cai, Jiabin

“…The combination of immunotherapy and molecular targeted therapy exhibits promising therapeutic efficacy in hepatocellular carcinoma (HCC), but the underlying…”
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Interleukin-8 as a candidate for thymoma identification and recurrence surveillance by Gao, Shilin, Jiang, Jiahao, Jin, Chun, Gao, Jian, Xiong, Dian, Yang, Pengjie, Cui, Shuzhong, Yang, Wenhao, Leng, Qibin, Dong, Jihong, Chen, Gang, Liu, Junzhen, Wang, Li, Ke, Aiwu, Wang, Haikun, Ding, Jianyong

“…Thymoma is the most common tumor of the anterior mediastinum. Routine imaging methods such as computed tomography or magnetic resonance imaging often lead to…”
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Circular RNA circEIF3C promotes intrahepatic cholangiocarcinoma progression and immune evasion via the miR-34a-5p/B7–H4 axis by Zhong, Xiaoming, Ji, Changxue, Ren, Dabin, Ke, Aiwu, Yang, Zhiwen

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Single-cell transcriptomic analysis suggests two molecularly distinct subtypes of intrahepatic cholangiocarcinoma by Song, Guohe, Shi, Yang, Meng, Lu, Ma, Jiaqiang, Huang, Siyuan, Zhang, Juan, Wu, Yingcheng, Li, Jiaxin, Lin, Youpei, Yang, Shuaixi, Rao, Dongning, Cheng, Yifei, Lin, Jian, Ji, Shuyi, Liu, Yuming, Jiang, Shan, Wang, Xiaoliang, Zhang, Shu, Ke, Aiwu, Wang, Xiaoying, Cao, Ya, Ji, Yuan, Zhou, Jian, Fan, Jia, Zhang, Xiaoming, Xi, Ruibin, Gao, Qiang

“…Intrahepatic cholangiocarcinoma (iCCA) is a highly heterogeneous cancer with limited understanding of its classification and tumor microenvironment. Here, by…”
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Expression of DNMT1 and DNMT3a are regulated by GLI1 in human pancreatic cancer by He, ShanShan, Wang, Feng, Yang, LiJuan, Guo, ChuanYong, Wan, Rong, Ke, AiWu, Xu, Ling, Hu, GuoYong, Xu, XuanFu, Shen, Jie, Wang, XingPeng

“…GLI1, as an indispensable transcriptional factor of Hedgehog signaling pathway, plays an important role in the development of pancreatic cancer (PC). DNA…”
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Integrated single cell and bulk sequencing analysis identifies tumor reactive CXCR6+ CD8 T cells as a predictor of immune infiltration and immunotherapy outcomes in hepatocellular carcinoma by Li, Xiaogang, Gao, Zheng, Chen, Jiafeng, Feng, Shanru, Luo, Xuanming, Shi, Yinghong, Tang, Zheng, Liu, Weiren, Zhang, Xin, Huang, Ao, Gao, Qiang, Ke, Aiwu, Zhou, Jian, Fan, Jia, Fu, Xiutao, Ding, Zhenbin

“…Background Various immune cell types in the tumor microenvironment (TME) of hepatocellular carcinoma (HCC) have been identified as important parameters…”
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Resveratrol Inhibits Proliferation and Induces Apoptosis through the Hedgehog Signaling Pathway in Pancreatic Cancer Cell by Mo, Wenhui, Xu, Xuanfu, Xu, Ling, Wang, Feng, Ke, Aiwu, Wang, Xingpeng, Guo, Chuanyong

“…Abstract Purpose: To investigate the effect and possible mechanisms of resveratrol on pancreatic cancer cells in vitro. Methods: After being treated with…”
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BRD4 promotes tumor growth and epithelial-mesenchymal transition in hepatocellular carcinoma by Zhang, Pengfei, Dong, Zhaoru, Cai, Jiabin, Zhang, Chi, Shen, Zaozhuo, Ke, Aiwu, Gao, Dongmei, Fan, Jia, Shi, Guoming

“…Bromodomain and extraterminal domain (BET) proteins are epigenetic readers that play an important role in chromatin remodeling and transcriptional regulation…”
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Quantitative acetylome analysis reveals histone modifications that may predict prognosis in hepatitis B‐related hepatocellular carcinoma by Chai, Xiaoqiang, Guo, Jianfei, Dong, Ruizhao, Yang, Xuan, Deng, Chao, Wei, Chuanyuan, Xu, JiaJie, Han, Weiyu, Lu, Jiacheng, Gao, Chao, Gao, Dongmei, Huang, Cheng, Ke, Aiwu, Li, Shuangqi, Li, Huanping, Tian, Yingming, Gu, Zhongkai, Liu, Shuxian, Liu, Hang, Chen, Qilong, Liu, Feng, Zhou, Jian, Fan, Jia, Shi, Guoming, Wu, Feizhen, Cai, Jiabin

“…Lysine acetylation (Kac) as an important posttranslational modification of histones is essential for the regulation of gene expression in hepatocellular…”
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Identification of RegIV as a novel GLI1 target gene in human pancreatic cancer by Wang, Feng, Xu, Ling, Guo, Chuanyong, Ke, Aiwu, Hu, Guoyong, Xu, Xuanfu, Mo, Wenhui, Yang, Lijuan, Huang, Yinshi, He, Shanshan, Wang, Xingpeng

“…GLI1 is the key transcriptional factor in the Hedgehog signaling pathway in pancreatic cancer. RegIV is associated with regeneration, and cell growth,…”
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Whole-Exome Sequencing-Based Mutational Profiling of Hepatitis B Virus-Related Early-Stage Hepatocellular Carcinoma by Fan, Jia, Zhou, Jian, Huang, Xiaowu, Luo, Chubin, Zhu, Kai, Hu, Zhiqiang, Hu, Jin-Wu, Ke, Aiwu, Sun, Qi-Man, Jiang, Jiahao, Zhan, Hao, Ren, Ning

“…Background. Hepatocellular carcinoma (HCC) ranks as the third leading cause of cancer-related mortality in China with increasing incidence. This study is…”
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The progress of immune checkpoint therapy in primary liver cancer by Zheng, Yimin, Wang, Siwei, Cai, Jiabin, Ke, Aiwu, Fan, Jia

“…After years of in-depth research on immune checkpoints, therapeutic reversal of immune-exhaustion with immune checkpoint inhibitors (ICPIs) has been shown to…”
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Ferroptosis and its interaction with tumor immune microenvironment in liver cancer by Huang, Yilan, Wang, Siwei, Ke, Aiwu, Guo, Kun

“…Exploring effective systemic treatments for liver cancer is still a great challenge worldwide. As a novel form of regulated cell death, ferroptosis has been…”
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Genome-wide mapping of 5-hydroxymethylcytosines in circulating cell-free DNA as a non-invasive approach for early detection of hepatocellular carcinoma by Cai, Jiabin, Chen, Lei, Zhang, Zhou, Zhang, Xinyu, Lu, Xingyu, Liu, Weiwei, Shi, Guoming, Ge, Yang, Gao, Pingting, Yang, Yuan, Ke, Aiwu, Xiao, Linlin, Dong, Ruizhao, Zhu, Yanjing, Yang, Xuan, Wang, Jiefei, Zhu, Tongyu, Yang, Deping, Huang, Xiaowu, Sui, Chengjun, Qiu, Shuangjian, Shen, Feng, Sun, Huichuan, Zhou, Weiping, Zhou, Jian, Nie, Ji, Zeng, Chang, Stroup, Emily Kunce, Zhang, Xu, Chiu, Brian C-H, Lau, Wan Yee, He, Chuan, Wang, Hongyang, Zhang, Wei, Fan, Jia

“…The lack of highly sensitive and specific diagnostic biomarkers is a major contributor to the poor outcomes of patients with hepatocellular carcinoma (HCC). We…”
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