Search Results - "Kazuma, Satoshi"

Recombinant thrombomodulin and recombinant antithrombin attenuate pulmonary endothelial glycocalyx degradation and neutrophil extracellular trap formation in ventilator-induced lung injury in the context of endotoxemia by Kikuchi, Kenichiro, Kazuma, Satoshi, Yamakage, Michiaki

“…Vascular endothelial damage is involved in the development and exacerbation of ventilator-induced lung injury (VILI). Pulmonary endothelial glycocalyx and…”
Get full text

Effect of linezolid on platelet count in critically ill patients with thrombocytopenia by Tatsumi, Hiroomi, Akatsuka, Masayuki, Kuroda, Hiromitsu, Kazuma, Satoshi, Suzuki, Shintaro, Masuda, Yoshiki

“…Linezolid (LZD) is one of the antibiotics used to treat methicillin-resistant Staphylococcus aureus. In Japan, the dose of LZD is not generally adjusted by…”
Get full text

Albumin protects the ultrastructure of the endothelial glycocalyx of coronary arteries in myocardial ischemia-reperfusion injury in vivo by Sawashita, Yasuaki, Kazuma, Satoshi, Tokinaga, Yasuyuki, Kikuchi, Kenichiro, Hirata, Naoyuki, Masuda, Yoshiki, Yamakage, Michiaki

“…Myocardial ischemia-reperfusion (I/R) injury induces endothelial glycocalyx (GCX) degradation. Several candidate GCX-protective factors including albumin have…”
Get full text

Comparative Study of TOF-Cuff, a New Neuromuscular Blockade Monitor, and TOF-Watch, an Acceleromyography by Kazuma, Satoshi, Wakasugi, Keiko, Hagiwara, Hiroya, Yamakage, Michiaki

“…Train-of-four ratios were recorded to assess the agreement between the TOF-Cuff and TOF-Watch, and residual paresis was assessed to evaluate the clinical…”
Get full text

Validation of the relationship between coagulopathy and localization of hydroxyethyl starch on the vascular endothelium in a rat hemodilution model by Azumaguchi, Ryu, Tokinaga, Yasuyuki, Kazuma, Satoshi, Kimizuka, Motonobu, Hamada, Kosuke, Sato, Tomoe, Yamakage, Michiaki

“…Various anticoagulant properties have been associated with hydroxyethyl starch (HES). However, the mechanism remains unclear and it has not been fully…”
Get full text

A Rapid Increase in Serum Lactate Levels after Cardiovascular Surgery Is Associated with Postoperative Serious Adverse Events: A Single Center Retrospective Study by Kikuchi, Kenichiro, Kazuma, Satoshi, Masuda, Yoshiki

“…Hyperlactatemia is a common predictive factor for poor post-cardiovascular surgery outcomes. However, it is not well understood whether the rapid postoperative…”
Get full text

Effects of anesthetic agents on contractions of the pregnant rat myometrium in vivo and in vitro by Kimizuka, Motonobu, Tokinaga, Yasuyuki, Azumaguchi, Ryu, Hamada, Kosuke, Kazuma, Satoshi, Yamakage, Michiaki

“…Background Several anesthetic agents are used in cesarean sections for both regional and general anesthesia purposes. However, there are no data comparing the…”
Get full text

Author Correction: Validation of the relationship between coagulopathy and localization of hydroxyethyl starch on the vascular endothelium in a rat hemodilution model by Azumaguchi, Ryu, Tokinaga, Yasuyuki, Kazuma, Satoshi, Kimizuka, Motonobu, Hamada, Kosuke, Sato, Tomoe, Yamakage, Michiaki

Get full text

Sevoflurane Promotes Regeneration of the Endothelial Glycocalyx by Upregulating Sialyltransferase by Kazuma, Satoshi, Tokinaga, Yasuyuki, Kimizuka, Motonobu, Azumaguchi, Ryu, Hamada, Kohsuke, Yamakage, Michiaki

“…During ischemia-reperfusion injury, the endothelial glycocalyx is damaged by oxidative stress-induced release of hydrogen peroxide, leading to decreased…”
Get full text

Improvement in ICU Mortality From Sepsis Associated With Recuperation From Septic Multiple-Organ Failure: A Retrospective, Single-Center, Cohort Study by Kikuchi, Kenichiro, Kazuma, Satoshi, Masuda, Yoshiki

“…Although mortality due to sepsis has decreased in recent decades, there are few studies on the timing of death during ICU stay. Characteristics of patients…”
Get full text

Frequent tracheal suctioning is associated with extubation failure in patients with successful spontaneous breathing trial: a single-center retrospective cohort study by Haruna, Junpei, Tatsumi, Hiroomi, Kazuma, Satoshi, Sasaki, Aki, Masuda, Yoshiki

“…Background Extubation failure, i.e., reintubation in ventilated patients, is a well-known risk factor for mortality and prolonged stay in the intensive care…”
Get full text

Effect of renal clearance on vancomycin area under the concentration–time curve deviations in critically ill patients by Ishigo, Tomoyuki, Ibe, Yuta, Fujii, Satoshi, Kazuma, Satoshi, Aigami, Tomohiro, Kashiwagi, Yuri, Takada, Ryo, Takahashi, Satoshi, Fukudo, Masahide, Toda, Takaki

“…Augmented renal clearance (ARC) increases vancomycin (VCM) clearance. Therefore, higher VCM doses are recommended in patients with ARC; however, impacts of ARC…”
Get full text

Clinical Effect of the Traditional Japanese Herbal Medicine "Goreisan" on Water Balance in Patients With Severe Acute Pancreatitis by Tatsumi, Hiroomi, Akatsuka, Masayuki, Kuroda, Hiromitsu, Kazuma, Satoshi, Masuda, Yoshiki

“…Since severe acute pancreatitis (SAP) involves inflammatory mediators produced by local inflammation of the pancreas that trigger a systemic inflammatory…”
Get full text

Association between Extended Meropenem Regimen and Achievement of Aggressive PK/PD in Patients Receiving Continuous Renal Replacement Therapy for Septic AKI by Chihara, Shinya, Ishigo, Tomoyuki, Kazuma, Satoshi, Matsumoto, Kana, Morita, Kunihiko, Masuda, Yoshiki

“…Aggressive pharmacokinetic (PK)/pharmacodynamic (PD) targets have shown better microbiological eradication rates and a lower propensity to develop resistant…”
Get full text

Recovery of postoperative cognitive function in elderly patients after a long duration of desflurane anesthesia: a pilot study by Tachibana, Shunsuke, Hayase, Tomo, Osuda, Michiko, Kazuma, Satoshi, Yamakage, Michiaki

“…Postoperative cognitive dysfunction (POCD) increases morbidity and mortality. The mechanisms underlying POCD remain elusive; however, systemic responses…”
Get full text

Practical approach to thrombocytopenia in patients with sepsis: a narrative review by Satoh, Kasumi, Wada, Takeshi, Tampo, Akihito, Takahashi, Gaku, Hoshino, Kota, Matsumoto, Hironori, Taira, Takayuki, Kazuma, Satoshi, Masuda, Takamitsu, Tagami, Takashi, Ishikura, Hiroyasu

“…Thrombocytopenia frequently occurs in patients with sepsis. Disseminated intravascular coagulation (DIC) may be a possible cause of thrombocytopenia owing to…”
Get full text

Using an ICU Diary to Communicate With Family Members of COVID-19 Patients in ICU: A Case Report by Haruna, Junpei, Tatsumi, Hiroomi, Kazuma, Satoshi, Kuroda, Hiromitsu, Goto, Yuya, Aisaka, Wakiko, Terada, Hirofumi, Masuda, Yoshiki

“…Visitation restrictions for family members are problematic in intensive care management due to the COVID-19 pandemic. We analyzed the usefulness of an…”
Get full text

Optimal target blood pressure in elderly with septic shock (OPTPRESS) trial: study protocol for a randomized controlled trial by Endo, Akira, Yamakawa, Kazuma, Tagami, Takashi, Umemura, Yutaka, Takahashi, Kyosuke, Nagasawa, Hiroki, Araki, Yuichi, Kojima, Mitsuaki, Sera, Toshiki, Yagi, Masayuki, Yamamoto, Ryo, Takahashi, Jiro, Nakane, Masaki, Takeda, Chikashi, Narita, Chihiro, Kazuma, Satoshi, Okura, Hiroko, Takahashi, Hiroyuki, Wada, Takeshi, Tahara, Shu, Matsuoka, Ayaka, Masaki, Todani, Shiraishi, Atsushi, Shimoyama, Keiichiro, Yokokawa, Yuta, Nakamura, Rintaro, Sageshima, Hisako, Yanagida, Yuichiro, Takahashi, Kunihiko, Otomo, Yasuhiro

“…Abstract Background Hemodynamic stabilization is a core component in the resuscitation of septic shock. However, the optimal target blood pressure remains…”
Get full text

Comparison of the National Early Warning Scores and Rapid Emergency Medicine Scores with the APACHE II Scores as a Prediction of Mortality in Patients with Medical Emergency Team Activation: A Single-centre Retrospective Cohort Study by Haruna, Junpei, Tatsumi, Hiroomi, Kazuma, Satoshi, Kuroda, Hiromitsu, Goto, Yuya, Aisaka, Wakiko, Terada, Hirofumi, Sonoda, Tomoko, Masuda, Yoshiki

“…Abstract Introduction The medical emergency team enables the limitation of patients’ progression to critical illness in the general ward. The early warning…”
Get full text

Desflurane inhibits endothelium-dependent vasodilation more than sevoflurane with inhibition of endothelial nitric oxide synthase by different mechanisms by Kazuma, Satoshi, Tokinaga, Yasuyuki, Takada, Yukimasa, Azumaguchi, Ryu, Kimizuka, Motonobu, Hayashi, Shunsuke, Yamakage, Michiaki

“…The effects of desflurane on endothelium-dependent vasodilation remain uncertain, whereas sevoflurane is known to inhibit it. Endothelium-dependent…”
Get full text