Search Results - "Kazuaki Harada"

Usefulness of ultrasonography and elastography in diagnosing oxaliplatin-induced sinusoidal obstruction syndrome by Saito, Rika, Kawamoto, Yasuyuki, Nishida, Mutsumi, Iwai, Takahito, Kikuchi, Yasuka, Yokota, Isao, Takagi, Ryo, Yamamura, Takahiro, Ito, Ken, Harada, Kazuaki, Yuki, Satoshi, Komatsu, Yoshito, Sakamoto, Naoya

“…Background Sinusoidal obstruction syndrome (SOS) refers to liver injury caused by hematopoietic stem cell transplantation (HSCT) and anticancer drugs including…”
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Soluble factors derived from neuroblastoma cell lines suppress dendritic cell differentiation and activation by Harada, Kazuaki, Ihara, Fumie, Takami, Mariko, Kamata, Toshiko, Mise, Naoko, Yoshizawa, Hiroko, Hishiki, Tomoro, Saito, Takeshi, Terui, Keita, Nakata, Mitsuyuki, Komatsu, Shugo, Ikeuchi, Takayuki, Nakayama, Toshinori, Yoshida, Hideo, Motohashi, Shinichiro

“…Dendritic cells (DC) play a key role in the initiation of both antitumor immunity and immunological tolerance. It has been demonstrated that exposure to…”
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Impact of single-heterozygous UGT1A1 on the clinical outcomes of irinotecan monotherapy after fluoropyrimidine and platinum-based combination therapy for gastric cancer: a multicenter retrospective study by Nakano, Shintaro, Yuki, Satoshi, Kawamoto, Yasuyuki, Nakatsumi, Hiroshi, Ando, Takayuki, Kajiura, Shinya, Yoshikawa, Ayumu, Harada, Kazuaki, Hatanaka, Kazuteru, Tanimoto, Aya, Ishiguro, Atsushi, Honda, Takuya, Dazai, Masayoshi, Sasaki, Takahide, Sakamoto, Naoya, Komatsu, Yoshito

“…Background It is unclear whether the UGT1A1 status, single heterozygous (SH) or wild type (WT), is associated with the efficacy and toxicity of irinotecan…”
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Comparative sequence analysis of patient-matched primary colorectal cancer, metastatic, and recurrent metastatic tumors after adjuvant FOLFOX chemotherapy by Harada, Kazuaki, Okamoto, Wataru, Mimaki, Sachiyo, Kawamoto, Yasuyuki, Bando, Hideaki, Yamashita, Riu, Yuki, Satoshi, Yoshino, Takayuki, Komatsu, Yoshito, Ohtsu, Atsushi, Sakamoto, Naoya, Tsuchihara, Katsuya

“…In the era of genome-guided personalized cancer treatment, we must understand chemotherapy-induced genomic changes in tumors. This study evaluated whether…”
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Analysis of the Pancreatic Cancer Microbiome Using Endoscopic Ultrasound–Guided Fine-Needle Aspiration–Derived Samples by Nakano, Shintaro, Kawamoto, Yasuyuki, Komatsu, Yoshito, Saito, Rika, Ito, Ken, Yamamura, Takahiro, Harada, Kazuaki, Yuki, Satoshi, Kawakubo, Kazumichi, Sugiura, Ryo, Kato, Shin, Hirata, Koji, Hirata, Hajime, Nakajima, Masahito, Furukawa, Ryutaro, Takishin, Yunosuke, Nagai, Kousuke, Yokota, Isao, Ota, Keisuke H., Nakaoka, Shinji, Kuwatani, Masaki, Sakamoto, Naoya

“…Most previous studies have analyzed bacteria in tumors using resected pancreatic cancer (PC) tissues, because it is difficult to obtain tissue samples from…”
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Anti-epidermal growth factor receptor treatment for patients with NeoRAS wild-type metastatic colorectal cancer: a case report of two cases by Harada, Kazuaki, Yuki, Satoshi, Kawamoto, Yasuyuki, Nakamura, Takeaki, Kaneko, Shiho, Ishida, Koichi, Sakamoto, Naoya, Komatsu, Yoshito

“…The NeoRAS phenomenon is defined as the conversion of tumor RAS status from mutant-type (MT) to wild-type (WT) after systemic chemotherapy in metastatic…”
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Multicenter, prospective, observational study of chemotherapy-induced dysgeusia in gastrointestinal cancer by Ito, Ken, Yuki, Satoshi, Nakatsumi, Hiroshi, Kawamoto, Yasuyuki, Harada, Kazuaki, Nakano, Shintaro, Saito, Rika, Ando, Takayuki, Sawada, Kentaro, Yagisawa, Masataka, Ishiguro, Atsushi, Dazai, Masayoshi, Iwanaga, Ichiro, Hatanaka, Kazuteru, Sato, Atsushi, Matsumoto, Ryusuke, Shindo, Yoshiaki, Tateyama, Miki, Muranaka, Tetsuhito, Katagiri, Masaki, Yokota, Isao, Sakata, Yuh, Sakamoto, Naoya, Komatsu, Yoshito

“…Purpose Dysgeusia is an adverse event caused by chemotherapy. Although retrospective studies have shown zinc administration improves dysgeusia, there have been…”
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Feasibility of a modified search, coagulation, and clipping method with and without the use of polyglycolic acid sheets and fibrin glue for preventing delayed bleeding after gastric endoscopic submucosal dissection by Abiko, Satoshi, Oda, Soichiro, Meno, Akimitsu, Shido, Akane, Yoshida, Sonoe, Yoshikawa, Ayumu, Harada, Kazuaki, Kawagishi, Naoki, Sano, Itsuki, Oda, Hisashi, Miyagishima, Takuto

“…Methods have been developed for preventing delayed bleeding (DB) after gastric endoscopic submucosal dissection (GESD). However, none of the methods can…”
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Study protocol for HGCSG1801: A multicenter, prospective, phase II trial of second-line FOLFIRI plus aflibercept in patients with metastatic colorectal cancer refractory to anti-EGFR antibodies by Nakatsumi, Hiroshi, Komatsu, Yoshito, Muranaka, Tetsuhito, Yuki, Satoshi, Kawamoto, Yasuyuki, Harada, Kazuaki, Dazai, Masayoshi, Tateyama, Miki, Sasaki, Yusuke, Miyagishima, Takuto, Tsuji, Yasushi, Katagiri, Masaki, Nakamura, Michio, Sogabe, Susumu, Hatanaka, Kazuteru, Meguro, Takashi, Kobayashi, Tomoe, Ishiguro, Atsushi, Muto, Osamu, Shindo, Yoshiaki, Kotaka, Masahito, Ando, Takayuki, Takagi, Ryo, Sakamoto, Naoya, Sakata, Yu

“…Background The first-line chemotherapy for patients with RAS and BRAF wild-type metastatic colorectal cancer (mCRC) commonly involves cytotoxic regimens, such…”
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Antibody‐dependent cellular cytotoxicity toward neuroblastoma enhanced by activated invariant natural killer T cells by Mise, Naoko, Takami, Mariko, Suzuki, Akane, Kamata, Toshiko, Harada, Kazuaki, Hishiki, Tomoro, Saito, Takeshi, Terui, Keita, Mitsunaga, Tetsuya, Nakata, Mitsuyuki, Ikeuchi, Takayuki, Nakayama, Toshinori, Yoshida, Hideo, Motohashi, Shinichiro

“…Anti‐ganglioside GD2 antibodies mainly work through antibody‐dependent cellular cytotoxicity (ADCC) and have demonstrated clinical benefit for children with…”
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Study protocol of the HGCSG1803: a phase II multicentre, non-randomised, single-arm, prospective trial of combination chemotherapy with oxaliplatin, irinotecan and S-1 (OX-IRIS) as first-line treatment for metastatic or relapsed pancreatic cancer by Nakano, Shintaro, Kawamoto, Yasuyuki, Yuki, Satoshi, Harada, Kazuaki, Miyagishima, Takuto, Sogabe, Susumu, Dazai, Masayoshi, Sato, Atsushi, Ishiguro, Atsushi, Nakamura, Michio, Kajiura, Shinya, Takahashi, Yasuo, Tateyama, Miki, Hatanaka, Kazuteru, Tsuji, Yasushi, Sasaki, Takahide, Shindo, Yoshiaki, Kobayashi, Tomoe, Yokota, Isao, Sakamoto, Naoya, Sakata, Yuh, Komatsu, Yoshito

“…IntroductionCombination chemotherapy with oxaliplatin, irinotecan, fluorouracil and leucovorin (FOLFIRINOX) has become one of the standard treatments for…”
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Maximum isometric tongue strength and tongue endurance in healthy adults by Hao, Grace, Chih, Yu‐Chun, Ni, Anpin, Harada, Kazuaki, Thompson, Jorde, Chen, Shiuan‐Chih, Chang, Yu‐Jung

“…Objective Tongue muscles play critical roles in swallowing function. This study was designed to investigate the tongue function of healthy individuals without…”
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Correlation of UGT1A1 Gene Polymorphisms or Prior Irinotecan Treatment and Treatment Outcomes of Nanoliposomal-Irinotecan plus 5-Fluorouracil/Leucovorin for Pancreatic Ductal Adenocarcinoma: A Multicenter, Retrospective Cohort Study (HGCSG2101) by Harada, Kazuaki, Yamamura, Takahiro, Muto, Osamu, Nakamura, Michio, Sogabe, Susumu, Sawada, Kentaro, Nakano, Shintaro, Yagisawa, Masataka, Muranaka, Tetsuhito, Dazai, Masayoshi, Tateyama, Miki, Kobayashi, Yoshimitsu, Kato, Sosuke, Hatanaka, Kazuteru, Kawamoto, Yasuyuki, Yuki, Satoshi, Sakata, Yuh, Sakamoto, Naoya, Komatsu, Yoshito

“…The effects of gene polymorphisms or prior irinotecan treatment on treatment outcomes of nanoliposomal-irinotecan plus 5-fluorouracil/leucovorin…”
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Pericardial tamponade during pembrolizumab treatment in a patient with advanced lung adenocarcinoma: A case report and review of the literature by Harada, Kazuaki, Ogasawara, Makoto, Shido, Akane, Meno, Akimitsu, Oda, Soichiro, Yoshida, Shota, Yoshida, Sonoe, Yoshikawa, Ayumu, Ebata, Ko, Abiko, Satoshi, Kawagishi, Naoki, Sano, Itsuki, Oda, Hisashi, Miyagishima, Takuto

“…Several studies have demonstrated increased pericardial effusion during anti‐PD‐1 immunotherapy, and treatment in patients who have developed pericardial…”
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Study protocol of HGCSG1404 SNOW study: a phase I/II trial of combined chemotherapy of S-1, nab-paclitaxel and oxaliplatin administered biweekly to patients with advanced gastric cancer by Kawamoto, Yasuyuki, Komatsu, Yoshito, Yuki, Satoshi, Sawada, Kentaro, Muranaka, Tetsuhito, Harada, Kazuaki, Nakatsumi, Hiroshi, Fukushima, Hiraku, Ishiguro, Atsushi, Dazai, Masayoshi, Hatanaka, Kazuteru, Nakamura, Michio, Iwanaga, Ichiro, Uebayashi, Minoru, Sogabe, Susumu, Kobayashi, Yoshimitsu, Miyagishima, Takuto, Ono, Kota, Sakamoto, Naoya, Sakata, Yuh

“…In Japan, S-1 plus cisplatin (SP) regimen has become a standard therapy for patients with advanced gastric cancer. Moreover, the S-1 plus oxaliplatin regimen…”
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Usefulness of procalcitonin serum level for the discrimination of severe sepsis from sepsis: a multicenter prospective study by Endo, Shigeatsu, Aikawa, Naoki, Fujishima, Seitaro, Sekine, Isao, Kogawa, Kazuhiro, Yamamoto, Yasuhiro, Kushimoto, Shigeki, Yukioka, Hidekazu, Kato, Noboru, Totsuka, Kyoichi, Kikuchi, Ken, Ikeda, Toshiaki, Ikeda, Kazumi, Yamada, Hiroyuki, Harada, Kazuaki, Satomura, Shinji

“…Abstract Procalcitonin serum level has been recommended as a new marker of bacterial infectious diseases. The aim of this prospective, multicenter study was to…”
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Efficacy and Safety of Bolus 5-Fluorouracil and L-Leucovorin as Salvage Chemotherapy for Oral Fluoropyrimidine-Resistant Unresectable or Recurrent Gastric Cancer: A Single Center Experience by Muranaka, Tetsuhito, Yuki, Satoshi, Komatsu, Yoshito, Sawada, Kentaro, Harada, Kazuaki, Kawamoto, Yasuyuki, Nakatsumi, Hiroshi, Sakamoto, Naoya

“…The International Organization for Standardization-5fluorouracil (FU) 10 trial found that bolus 5-FU and l-leucovorin was not inferior to S-1 in the treatment…”
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Design of a simple evolutionary multiobjective optimization method based on the combined use of scalarization and particle swarm optimization by Masuda, Kazuaki, Harada, Kazuaki, Kurihara, Kenzo

“…This paper proposes a general methodology of multiobjective optimization based on the combined use of scalarization and evolutionary computation approaches…”
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Multicenter prospective study of procalcitonin as an indicator of sepsis by Aikawa, Naoki, Fujishima, Seitaro, Endo, Shigeatu, Sekine, Isao, Kogawa, Kazuhiro, Yamamoto, Yasuhiro, Kushimoto, Shigeki, Yukioka, Hidekazu, Kato, Noboru, Totsuka, Kyoichi, Kikuchi, Ken, Ikeda, Toshiaki, Ikeda, Kazumi, Harada, Kazuaki, Satomura, Shinji

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Retrospective analysis of drug intake affecting the intestinal microbiota and the therapeutic effects of chemotherapy on gastric cancer by Nakamura, Takeaki, Watanabe, Ryosuke, Yamamura, Takahiro, Harada, Kazuaki, Kawamoto, Yasuyuki, Yuki, Satoshi, Sakamoto, Naoya, Komatsu, Yoshito

“…379 Background: Administration of some medications, such as antibiotics, antacids, and probiotic supplementation, may affects the treatment outcomes of immune…”
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