Search Results - "Kazuaki Chayama"

Prevalence and associated metabolic factors of nonalcoholic fatty liver disease in the general population from 2009 to 2010 in Japan: a multicenter large retrospective study by Eguchi, Yuichiro, Hyogo, Hideyuki, Ono, Masafumi, Mizuta, Toshihiko, Ono, Naofumi, Fujimoto, Kazuma, Chayama, Kazuaki, Saibara, Toshiji

“…Background The prevalence of nonalcoholic fatty liver disease (NAFLD) has been increasing. This study aimed to assess the recent prevalence of NAFLD and to…”
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Evidence-based clinical practice guidelines for Liver Cirrhosis 2020 by Yoshiji, Hitoshi, Nagoshi, Sumiko, Akahane, Takemi, Asaoka, Yoshinari, Ueno, Yoshiyuki, Ogawa, Koji, Kawaguchi, Takumi, Kurosaki, Masayuki, Sakaida, Isao, Shimizu, Masahito, Taniai, Makiko, Terai, Shuji, Nishikawa, Hiroki, Hiasa, Yoichi, Hidaka, Hisashi, Miwa, Hiroto, Chayama, Kazuaki, Enomoto, Nobuyuki, Shimosegawa, Tooru, Takehara, Tetsuo, Koike, Kazuhiko

“…The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010, and the second edition was published in 2015 by the Japanese…”
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Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 2020 by Tokushige, Katsutoshi, Ikejima, Kenichi, Ono, Masafumi, Eguchi, Yuichiro, Kamada, Yoshihiro, Itoh, Yoshito, Akuta, Norio, Yoneda, Masato, Iwasa, Motoh, Yoneda, Masashi, Otsuka, Motoyuki, Tamaki, Nobuharu, Kogiso, Tomomi, Miwa, Hiroto, Chayama, Kazuaki, Enomoto, Nobuyuki, Shimosegawa, Tooru, Takehara, Tetsuo, Koike, Kazuhiko

“…Nonalcoholic fatty liver disease (NAFLD) has become a serious public health issue not only in Western countries but also in Japan. Within the wide spectrum of…”
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MicroRNAs as Biomarkers for Liver Disease and Hepatocellular Carcinoma by Hayes, C Nelson, Chayama, Kazuaki

“…Serum levels of liver enzymes, such as alanine transaminase, aspartate transaminase, and α-fetoprotein, provide insight into liver function and are used during…”
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A nationwide survey on non-B, non-C hepatocellular carcinoma in Japan: 2011–2015 update by Tateishi, Ryosuke, Uchino, Koji, Fujiwara, Naoto, Takehara, Tetsuo, Okanoue, Takeshi, Seike, Masataka, Yoshiji, Hitoshi, Yatsuhashi, Hiroshi, Shimizu, Masahito, Torimura, Takuji, Moriyama, Mitsuhiko, Sakaida, Isao, Okada, Hiroyuki, Chiba, Tetsuhiro, Chuma, Makoto, Nakao, Kazuhiko, Isomoto, Hajime, Sasaki, Yutaka, Kaneko, Shuichi, Masaki, Tsutomu, Chayama, Kazuaki, Koike, Kazuhiko

“…Background We previously reported that the incidence of hepatocellular carcinoma (HCC) with non-viral etiologies increased rapidly between 1991 and 2010 in…”
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Computer-aided diagnosis of colorectal polyp histology by using a real-time image recognition system and narrow-band imaging magnifying colonoscopy by Kominami, Yoko, MD, Yoshida, Shigeto, MD, PhD, Tanaka, Shinji, MD, PhD, Sanomura, Yoji, MD, PhD, Hirakawa, Tsubasa, ME, Raytchev, Bisser, PhD, Tamaki, Toru, PhD, Koide, Tetsusi, PhD, Kaneda, Kazufumi, PhD, Chayama, Kazuaki, MD, PhD

“…Background and Aims It is necessary to establish cost-effective examinations and treatments for diminutive colorectal tumors that consider the treatment risk…”
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Hepatitis B virus evades innate immunity of hepatocytes but activates cytokine production by macrophages by Cheng, Xiaoming, Xia, Yuchen, Serti, Elisavet, Block, Peter Daniel, Chung, Michelle, Chayama, Kazuaki, Rehermann, Barbara, Liang, T. Jake

“…Hepatitis B virus (HBV) infects hepatocytes specifically and causes immune‐mediated liver damage. How HBV interacts with the innate immunity at the early phase…”
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Evidence‐based clinical practice guidelines for liver cirrhosis 2020 by Yoshiji, Hitoshi, Nagoshi, Sumiko, Akahane, Takemi, Asaoka, Yoshinari, Ueno, Yoshiyuki, Ogawa, Koji, Kawaguchi, Takumi, Kurosaki, Masayuki, Sakaida, Isao, Shimizu, Masahito, Taniai, Makiko, Terai, Shuji, Nishikawa, Hiroki, Hiasa, Yoichi, Hidaka, Hisashi, Miwa, Hiroto, Chayama, Kazuaki, Enomoto, Nobuyuki, Shimosegawa, Tooru, Takehara, Tetsuo, Koike, Kazuhiko

“…The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010, and the second edition was published in 2015 by the Japanese…”
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Role of tumor‐associated macrophages at the invasive front in human colorectal cancer progression by Inagaki, Katsuaki, Kunisho, Shoma, Takigawa, Hidehiko, Yuge, Ryo, Oka, Shiro, Tanaka, Shinji, Shimamoto, Fumio, Chayama, Kazuaki, Kitadai, Yasuhiko

“…Macrophages are an essential component of antitumor activity; however, the role of tumor‐associated macrophages (TAMs) in colorectal cancer (CRC) remains…”
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Clinical impact and characteristics of the narrow-band imaging magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team by Sumimoto, Kyoku, MD, Tanaka, Shinji, MD, PhD, Shigita, Kenjiro, MD, Hirano, Daiki, MD, Tamaru, Yuzuru, MD, Ninomiya, Yuki, MD, Asayama, Naoki, MD, Hayashi, Nana, MD, PhD, Oka, Shiro, MD, PhD, Arihiro, Koji, MD, PhD, Yoshihara, Masaharu, MD, PhD, Chayama, Kazuaki, MD, PhD

“…Background and Aims The Japan NBI Expert Team (JNET) was established in 2011 and has proposed a universal narrow-band imaging (NBI) magnifying endoscopic…”
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Characteristics and Early Diagnosis of Gastric Cancer Discovered after Helicobacter pylori Eradication by Ito, Masanori, Tanaka, Shinji, Chayama, Kazuaki

“…The prevalence of gastric cancer after eradication (GCAE) is increasing dramatically in Japan. GCAE has characteristic features, and we must understand these…”
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Road to elimination of HCV: Clinical challenges in HCV management by Hayes, C. Nelson, Imamura, Michio, Tanaka, Junko, Chayama, Kazuaki

“…Since its discovery in 1989, the road to a cure for hepatitis C virus (HCV) has been slow, but most patients can now expect to achieve a sustained virological…”
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Evidence‐based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 2020 by Tokushige, Katsutoshi, Ikejima, Kenichi, Ono, Masafumi, Eguchi, Yuichiro, Kamada, Yoshihiro, Itoh, Yoshito, Akuta, Norio, Yoneda, Masato, Iwasa, Motoh, Yoneda, Masashi, Otsuka, Motoyuki, Tamaki, Nobuharu, Kogiso, Tomomi, Miwa, Hiroto, Chayama, Kazuaki, Enomoto, Nobuyuki, Shimosegawa, Tooru, Takehara, Tetsuo, Koike, Kazuhiko

“…Nonalcoholic fatty liver disease (NAFLD) has become a serious public health issue not only in Western countries but also in Japan. Within the wide spectrum of…”
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Individual patient data meta-analysis of controlled attenuation parameter (CAP) technology for assessing steatosis by Karlas, Thomas, Petroff, David, Sasso, Magali, Fan, Jian-Gao, Mi, Yu-Qiang, de Lédinghen, Victor, Kumar, Manoj, Lupsor-Platon, Monica, Han, Kwang-Hyub, Cardoso, Ana C, Ferraioli, Giovanna, Chan, Wah-Kheong, Wong, Vincent Wai-Sun, Myers, Robert P, Chayama, Kazuaki, Friedrich-Rust, Mireen, Beaugrand, Michel, Shen, Feng, Hiriart, Jean-Baptiste, Sarin, Shiv K, Badea, Radu, Jung, Kyu Sik, Marcellin, Patrick, Filice, Carlo, Mahadeva, Sanjiv, Wong, Grace Lai-Hung, Crotty, Pam, Masaki, Keiichi, Bojunga, Joerg, Bedossa, Pierre, Keim, Volker, Wiegand, Johannes

“…Graphical abstract…”
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Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations by Wardell, Christopher P., Fujita, Masashi, Yamada, Toru, Simbolo, Michele, Fassan, Matteo, Karlic, Rosa, Polak, Paz, Kim, Jaegil, Hatanaka, Yutaka, Maejima, Kazuhiro, Lawlor, Rita T., Nakanishi, Yoshitsugu, Mitsuhashi, Tomoko, Fujimoto, Akihiro, Furuta, Mayuko, Ruzzenente, Andrea, Conci, Simone, Oosawa, Ayako, Sasaki-Oku, Aya, Nakano, Kaoru, Tanaka, Hiroko, Yamamoto, Yujiro, Michiaki, Kubo, Kawakami, Yoshiiku, Aikata, Hiroshi, Ueno, Masaki, Hayami, Shinya, Gotoh, Kunihito, Ariizumi, Shun-ichi, Yamamoto, Masakazu, Yamaue, Hiroki, Chayama, Kazuaki, Miyano, Satoru, Getz, Gad, Scarpa, Aldo, Hirano, Satoshi, Nakamura, Toru, Nakagawa, Hidewaki

“…[Display omitted] •Biliary tract cancers are clinically and genetically heterogeneous.•32 significantly mutated genes were identified, some negatively…”
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Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes by Xue, Ruidong, Chen, Lu, Zhang, Chong, Fujita, Masashi, Li, Ruoyan, Yan, Shu-Mei, Ong, Choon Kiat, Liao, Xiwen, Gao, Qiang, Sasagawa, Shota, Li, Yanmeng, Wang, Jincheng, Guo, Hua, Huang, Qi-Tao, Zhong, Qian, Tan, Jing, Qi, Lisha, Gong, Wenchen, Hong, Zhixian, Li, Meng, Zhao, Jingmin, Peng, Tao, Lu, Yinying, Lim, Kiat Hon Tony, Boot, Arnoud, Ono, Atushi, Chayama, Kazuaki, Zhang, Zemin, Rozen, Steve George, Teh, Bin Tean, Wang, Xin Wei, Nakagawa, Hidewaki, Zeng, Mu-Sheng, Bai, Fan, Zhang, Ning

“…We performed genomic and transcriptomic sequencing of 133 combined hepatocellular and intrahepatic cholangiocarcinoma (cHCC-ICC) cases, including separate,…”
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Clinical significance of endoscopic ultrasonography in diagnosing invasion depth of early gastric cancer prior to endoscopic submucosal dissection by Kuroki, Kazutaka, Oka, Shiro, Tanaka, Shinji, Yorita, Naoki, Hata, Kosaku, Kotachi, Takahiro, Boda, Tomoyuki, Arihiro, Koji, Chayama, Kazuaki

“…Background and aim Endoscopic ultrasonography is a reliable diagnostic modality for determining indications of endoscopic submucosal dissection for early…”
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Involvement of non-Helicobacter pylori helicobacter infections in Helicobacter pylori-negative gastric MALT lymphoma pathogenesis and efficacy of eradication therapy by Takigawa, Hidehiko, Yuge, Ryo, Masaki, Satoshi, Otani, Rina, Kadota, Hiroki, Naito, Toshikatsu, Hayashi, Ryohei, Urabe, Yuji, Oka, Shiro, Tanaka, Shinji, Chayama, Kazuaki, Kitadai, Yasuhiko

“…Background Eradication therapy is known to be effective against Helicobacter pylori -positive gastric MALT lymphoma but predicting the efficacy of eradication…”
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Modeling suggests that virion production cycles within individual cells is key to understanding acute hepatitis B virus infection kinetics by Hailegiorgis, Atesmachew, Ishida, Yuji, Collier, Nicholson, Imamura, Michio, Shi, Zhenzhen, Reinharz, Vladimir, Tsuge, Masataka, Barash, Danny, Hiraga, Nobuhiko, Yokomichi, Hiroshi, Tateno, Chise, Ozik, Jonathan, Uprichard, Susan L, Chayama, Kazuaki, Dahari, Harel

“…Hepatitis B virus (HBV) infection kinetics in immunodeficient mice reconstituted with humanized livers from inoculation to steady state is highly dynamic…”
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Long-term outcomes after endoscopic submucosal dissection for superficial colorectal tumors by Shigita, Kenjiro, MD, Oka, Shiro, MD, PhD, Tanaka, Shinji, MD, PhD, Sumimoto, Kyoku, MD, Hirano, Daiki, MD, Tamaru, Yuzuru, MD, Ninomiya, Yuki, MD, Asayama, Naoki, MD, Hayashi, Nana, MD, PhD, Shimamoto, Fumio, MD, PhD, Arihiro, Koji, MD, PhD, Chayama, Kazuaki, MD, PhD

“…Background and Aims Endoscopic submucosal dissection (ESD) is an effective procedure for en bloc resection of superficial colorectal tumors regardless of tumor…”
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