Search Results - "Kazmier, Kelli"

An improved lysozyme substrate preparation method for the biochemistry kinetics laboratory by Bodor, Koppany, Kazmier, Kelli N.

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Investigation of conformational sampling of LeuT due to Na site mutations at thr 354 and ser 355 with DEER EPR spectroscopy by Elson, Brynn E., Kazmier, Kelli N., Stein, Richard A.

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The role of K288A in conformational selection in LeuT by Rothfuss, Spencer J., Stein, Richard A., Kazmier, Kelli N.

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Alternating access mechanisms of LeuT-fold transporters: trailblazing towards the promised energy landscapes by Kazmier, Kelli, Claxton, Derek P, Mchaourab, Hassane S

“…[Display omitted] •Alternating access in the LeuT-fold class of transporters is discussed.•Structural analysis suggests mechanistic divergence among class…”
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Conformational dynamics and pH-regulation in ApcT by Kazmier, Kelli N., Peng, Dungeng, Verhalen, Brandy, Matthieu, Jeanette, Quick, Matthias, Stein, Richard A., Mchaourab, Hassane S.

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Conformational dynamics of ligand-dependent alternating access in LeuT by Kazmier, Kelli, Sharma, Shruti, Quick, Matthias, Islam, Shahidul M, Roux, Benoît, Weinstein, Harel, Javitch, Jonathan A, Mchaourab, Hassane S

“…LeuT is a Na + -coupled amino acid transporter that is similar in sequence and function to eukaryotic neurotransmitter/sodium symporters, which are active in…”
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Conformational cycle and ion-coupling mechanism of the Na⁺/hydantoin transporter Mhp1 by Kazmier, Kelli, Sharma, Shruti, Islam, Shahidul M., Roux, Benoît, Mchaourab, Hassane S.

“…Significance Na ⁺-coupled symporters use the cellular Na ⁺ gradient to power transport of physiologically important molecules across the lipid membrane…”
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Navigating Membrane Protein Structure, Dynamics, and Energy Landscapes Using Spin Labeling and EPR Spectroscopy by Claxton, Derek P, Kazmier, Kelli, Mishra, Smriti, Mchaourab, Hassane S

“…A detailed understanding of the functional mechanism of a protein entails the characterization of its energy landscape. Achieving this ambitious goal requires…”
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Conformational transitions of the sodium-dependent sugar transporter, vSGLT by Paz, Aviv, Claxton, Derek P., Kumar, Jay Prakash, Kazmier, Kelli, Bisignano, Paola, Sharma, Shruti, Nolte, Shannon A., Liwag, Terrin M., Nayak, Vinod, Wright, Ernest M., Grabe, Michael, Mchaourab, Hassane S., Abramson, Jeff

“…Sodium-dependent transporters couple the flow of Na⁺ ions down their electrochemical potential gradient to the uphill transport of various ligands. Many of…”
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Toward the Fourth Dimension of Membrane Protein Structure: Insight into Dynamics from Spin-Labeling EPR Spectroscopy by Mchaourab, Hassane S., Steed, P. Ryan, Kazmier, Kelli

“…Trapping membrane proteins in the confines of a crystal lattice obscures dynamic modes essential for interconversion between multiple conformations in the…”
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Algorithm for selection of optimized EPR distance restraints for de novo protein structure determination by Kazmier, Kelli, Alexander, Nathan S., Meiler, Jens, Mchaourab, Hassane S.

“…A hybrid protein structure determination approach combining sparse Electron Paramagnetic Resonance (EPR) distance restraints and Rosetta de novo protein…”
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Ligand-Dependent Conformational Cycle of the Na+/Hydantoin Transporter Mhp1 by Kazmier, Kelli, Sharma, Shruti, Islam, Shahidul M., Roux, Benoit, Mchaourab, Hassane S.

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Revealing the Transport Cycle Dynamics of the Sodium Dependent Sugar Transporter by Double Electron-Electron Resonance and Wide-Angle X-ray Scattering by Paz, Aviv, Claxton, Derek P., Sharma, Shruti, Kazmier, Kelli, Prakash Kumar, Jay, Nolte, Shannon A., Liwag, Terrin M., Mchaourab, Hassane S., Abramson, Jeff

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Structure, Dynamics, and Mechanism of the Leucine Transporter Studied by Double Electron Electron Resonance Spectroscopy by Kazmier, Kelli, Quick, Matthias, Shi, Lei, Weinstein, Harel, Javitch, Jonathan A., Mchaourab, Hassane S.

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Optimal Selection of EPR Distance Restraints for Global Folding of Protein Structure by Kazmier, Kelli, Alexander, Nathan S., Meiler, Jens, Mchaourab, Hassane S.

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Calculation of the EPR Spectrum of a Small Nitroxide from Molecular Dynamics Simulations by Kazmier, Kelli N., Lybrand, Terry P., Hustedt, Eric J.

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Revealing the Mechanistic Diversity of the LeuT Fold: A Comparative Analysis of the Leucine Transporter and the Hydantoin Transporter using Electron Paramagnetic Resonance Spectroscopy by Kazmier, Kelli Nicole

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