Search Results - "Kazi, Misha I."

Colistin heteroresistance in Enterobacter cloacae is regulated by PhoPQ‐dependent 4‐amino‐4‐deoxy‐l‐arabinose addition to lipid A by Kang, Katie N., Klein, Dustin R., Kazi, Misha I., Guérin, François, Cattoir, Vincent, Brodbelt, Jennifer S., Boll, Joseph M.

“…Summary The Enterobacter cloacae complex (ECC) consists of closely related bacteria commonly associated with the human microbiota. ECC are increasingly…”
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Multiple resistance factors collectively promote inoculum-dependent dynamic survival during antimicrobial peptide exposure in Enterobacter cloacae by Murtha, Andrew N, Kazi, Misha I, Kim, Eileen Y, Torres, Facundo V, Rosch, Kelly M, Dörr, Tobias

“…Antimicrobial peptides (AMPs) are a promising tool with which to fight rising antibiotic resistance. However, pathogenic bacteria are equipped with several AMP…”
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High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications by Murtha, Andrew N, Kazi, Misha I, Schargel, Richard D, Cross, Trevor, Fihn, Conrad, Cattoir, Vincent, Carlson, Erin E, Boll, Joseph M, Dörr, Tobias

“…Antibiotic tolerance is an understudied potential contributor to antibiotic treatment failure and the emergence of multidrug-resistant bacteria. The molecular…”
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ToxR Antagonizes H-NS Regulation of Horizontally Acquired Genes to Drive Host Colonization by Kazi, Misha I, Conrado, Aaron R, Mey, Alexandra R, Payne, Shelley M, Davies, Bryan W

“…The virulence regulator ToxR initiates and coordinates gene expression needed by Vibrio cholerae to colonize the small intestine and cause disease. Despite its…”
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Peptidoglycan Recycling Promotes Outer Membrane Integrity and Carbapenem Tolerance in Acinetobacter baumannii by Islam, Nowrosh, Kazi, Misha I, Kang, Katie N, Biboy, Jacob, Gray, Joe, Ahmed, Feroz, Schargel, Richard D, Boutte, Cara C, Dörr, Tobias, Vollmer, Waldemar, Boll, Joseph M

“…β-Lactam antibiotics exploit the essentiality of the bacterial cell envelope by perturbing the peptidoglycan layer, typically resulting in rapid lysis and…”
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Septal Class A Penicillin-Binding Protein Activity and ld-Transpeptidases Mediate Selection of Colistin-Resistant Lipooligosaccharide-Deficient Acinetobacter baumannii by Kang, Katie N, Kazi, Misha I, Biboy, Jacob, Gray, Joe, Bovermann, Hannah, Ausman, Jessie, Boutte, Cara C, Vollmer, Waldemar, Boll, Joseph M

“…Despite dogma suggesting that lipopolysaccharide/lipooligosaccharide (LOS) was essential for viability of Gram-negative bacteria, several clinical isolates…”
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In Mycobacterium abscessus , the Stringent Factor Rel Regulates Metabolism but Is Not the Only (p)ppGpp Synthase by Hunt-Serracín, Augusto César, Kazi, Misha I, Boll, Joseph M, Boutte, Cara C

“…The stringent response is a broadly conserved stress response system that exhibits functional variability across bacterial clades. Here, we characterize the…”
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Generating Transposon Insertion Libraries in Gram-Negative Bacteria for High-Throughput Sequencing by Kazi, Misha I, Schargel, Richard D, Boll, Joseph M

“…Transposon sequencing (Tn-seq) is a powerful method that combines transposon mutagenesis and massive parallel sequencing to identify genes and pathways that…”
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Exploring the Antimicrobial Action of Quaternary Amines against Acinetobacter baumannii by Knauf, Gregory A, Cunningham, Ashley L, Kazi, Misha I, Riddington, Ian M, Crofts, Alexander A, Cattoir, Vincent, Trent, M Stephen, Davies, Bryan W

“…Quaternary amine compounds (QAC) are potent antimicrobials used to prevent the spread of pathogenic bacteria. While they are known for their membrane-damaging…”
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Discovery and characterization of New Delhi metallo-β-lactamase-1 inhibitor peptides that potentiate meropenem-dependent killing of carbapenemase-producing Enterobacteriaceae by Kazi, Misha I, Perry, Blair W, Card, Daren C, Schargel, Richard D, Ali, Hana B, Obuekwe, Victor C, Sapkota, Madhab, Kang, Katie N, Pellegrino, Mark W, Greenberg, David E, Castoe, Todd A, Boll, Joseph M

“…Abstract Objectives Metallo-β-lactamases (MBLs) are an emerging class of antimicrobial resistance enzymes that degrade β-lactam antibiotics, including…”
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Exploring the Antimicrobial Action of Quaternary Amines against italic toggle="yes">Acinetobacter baumannii /italic by Gregory A. Knauf, Ashley L. Cunningham, Misha I. Kazi, Ian M. Riddington, Alexander A. Crofts, Vincent Cattoir, M. Stephen Trent, Bryan W. Davies

“…ABSTRACT Quaternary amine compounds (QAC) are potent antimicrobials used to prevent the spread of pathogenic bacteria. While they are known for their…”
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