Search Results - "Kazi, Hala"

High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice by Arnold, Steven E, Lucki, Irwin, Brookshire, Bethany R, Carlson, Gregory C, Browne, Caroline A, Kazi, Hala, Bang, Sookhee, Choi, Bo-Ran, Chen, Yong, McMullen, Mary F, Kim, Sangwon F

“…Abstract Insulin resistance and other features of the metabolic syndrome are increasingly recognized for their effects on cognitive health. To ascertain…”
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Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia by Carlson, Gregory C, Talbot, Konrad, Halene, Tobias B, Gandal, Michael J, Kazi, Hala A, Schlosser, Laura, Phung, Quan H, Gur, Raquel E, Arnold, Steven E, Siegel, Steven J

“…DTNBP1 (dystrobrevin binding protein 1) is a leading candidate susceptibility gene in schizophrenia and is associated with working memory capacity in normal…”
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Akt1 deficiency in schizophrenia and impairment of hippocampal plasticity and function by Balu, Darrick T., Carlson, Gregory C., Talbot, Konrad, Kazi, Hala, Hill-Smith, Tiffany E., Easton, Rachel M., Birnbaum, Morris J., Lucki, Irwin

“…Genetic studies have associated deficient function of the serine/threonine kinase Akt1 with schizophrenia. This disorder is associated with developmental,…”
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Synaptic dysbindin-1 reductions in schizophrenia occur in an isoform-specific manner indicating their subsynaptic location by Talbot, Konrad, Louneva, Natalia, Cohen, Julia W, Kazi, Hala, Blake, Derek J, Arnold, Steven E

“…An increasing number of studies report associations between variation in DTNBP1, a top candidate gene in schizophrenia, and both the clinical symptoms of the…”
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Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin by TALBOT, Konrad, CHO, Dan-Sung, ONG, Wei-Yi, BENSON, Matthew A, HAN, Li-Ying, KAZI, Hala A, KAMINS, Joshua, HAHN, Chang-Gyu, BLAKE, Derek J, ARNOLD, Steven E

“…Variations in the gene encoding the novel protein dysbindin-1 (DTNBP1) are among the most commonly reported genetic variations associated with schizophrenia…”
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Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline by Talbot, Konrad, Wang, Hoau-Yan, Kazi, Hala, Han, Li-Ying, Bakshi, Kalindi P, Stucky, Andres, Fuino, Robert L, Kawaguchi, Krista R, Samoyedny, Andrew J, Wilson, Robert S, Arvanitakis, Zoe, Schneider, Julie A, Wolf, Bryan A, Bennett, David A, Trojanowski, John Q, Arnold, Steven E

“…While a potential causal factor in Alzheimer's disease (AD), brain insulin resistance has not been demonstrated directly in that disorder. We provide such a…”
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An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers by Bomfim, Theresa R, Forny-Germano, Leticia, Sathler, Luciana B, Brito-Moreira, Jordano, Houzel, Jean-Christophe, Decker, Helena, Silverman, Michael A, Kazi, Hala, Melo, Helen M, McClean, Paula L, Holscher, Christian, Arnold, Steven E, Talbot, Konrad, Klein, William L, Munoz, Douglas P, Ferreira, Sergio T, De Felice, Fernanda G

“…Defective brain insulin signaling has been suggested to contribute to the cognitive deficits in patients with Alzheimer's disease (AD). Although a connection…”
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Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer’s disease and tauopathies by Yarchoan, Mark, Toledo, Jon B., Lee, Edward B., Arvanitakis, Zoe, Kazi, Hala, Han, Li-Ying, Louneva, Natalia, Lee, Virginia M.-Y., Kim, Sangwon F., Trojanowski, John Q., Arnold, Steven E.

“…Neuronal insulin signaling abnormalities have been associated with Alzheimer’s disease (AD). However, the specificity of this association and its underlying…”
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Olfactory epithelium amyloid-β and paired helical filament-tau pathology in Alzheimer disease by Arnold, Steven E., Lee, Edward B., Moberg, Paul J., Stutzbach, Lauren, Kazi, Hala, Han, Li-Ying, Lee, Virginia M. Y., Trojanowski, John Q.

“…Objective Olfactory dysfunction is common in Alzheimer disease (AD) and other neurodegenerative diseases. Paired helical filament (PHF)‐tau, α‐synuclein, and…”
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Neuronal Activity-Induced Sterol Regulatory Element Binding Protein-1 (SREBP1) is Disrupted in Dysbindin-Null Mice—Potential Link to Cognitive Impairment in Schizophrenia by Chen, Yong, Bang, Sookhee, McMullen, Mary F., Kazi, Hala, Talbot, Konrad, Ho, Mei-Xuan, Carlson, Greg, Arnold, Steven E., Ong, Wei-Yi, Kim, Sangwon F.

“…Schizophrenia is a chronic debilitating neuropsychiatric disorder that affects about 1 % of the population. Dystrobrevin-binding protein 1 (DTNBP1 or…”
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Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia by Carlson, Gregory C., Talbot, Konrad, Halene, Tobias B., Gandal, Michael J., Kazi, Hala A., Schlosser, Laura, Phung, Quan H., Gur, Raquel E., Arnold, Steven E., Siegel, Steven J.

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Association between in vivo fluorine 18-labeled flutemetamol amyloid positron emission tomography imaging and in vivo cerebral cortical histopathology by Wolk, David A, Grachev, Igor D, Buckley, Chris, Kazi, Hala, Grady, M Sean, Trojanowski, John Q, Hamilton, Roy H, Sherwin, Paul, McLain, Richard, Arnold, Steven E

“…To determine the correspondence of in vivo quantitative estimates of brain uptake of fluorine 18-labeled flutemetamol with immunohistochemical estimates of…”
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O5‐01‐01: Anti‐diabetic drugs protect the brain from defective insulin signaling caused by Alzheimer's toxic Aß oligomers by Bomfim, Theresa, Forny‐Germano, Leticia, Silverman, Michael, Kazi, Hala, Arnold, Steven, Talbot, Konrad, Klein, William, Muñoz, Douglas, Ferreira, Sergio, De Felice, Fernanda

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Anti-diabetic drugs protect the brain from defective insulin signaling caused by Alzheimer's toxic Aß oligomers by Bomfim, Theresa, Forny-Germano, Leticia, Silverman, Michael, Kazi, Hala, Arnold, Steven, Talbot, Konrad, Klein, William, Muñoz, Douglas, Ferreira, Sergio, De Felice, Fernanda

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An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease-associated A[Beta] oligomers by Bomfim, Theresa R, ny-Germano, Leticia, Sathler, Luciana B, Brito-Moreira, Jordano, Houzel, Jean-Christophe, Decker, Helena, Silverman, Michael A, Kazi, Hala, Melo, Helen M, McClean, Paula L, Holscher, Christian, Arnold, Steven E, Talbot, Konrad, Klein, William L, Munoz, Douglas P, Ferreira, Sergio T, De Felice, Fernanda G

“…Defective brain insulin signaling has been suggested to contribute to the cognitive deficits in patients with Alzheimer's disease (AD). Although a connection…”
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Olfactory Epithelium Amyloid-β and PHFtau Pathology in Alzheimer’s Disease by Arnold, Steven E., Lee, Edward B., Moberg, Paul J., Stutzbach, Lauren, Kazi, Hala, Han, Li-Ying, Lee, Virginia M.Y., Trojanowski, John Q.

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Olfactory epithelium amyloid-b and paired helical filament-tau pathology in Alzheimer disease by Arnold, Steven E, Lee, Edward B, Moberg, Paul J, Stutzbach, Lauren, Kazi, Hala, Han, Li-Ying, Lee, Virginia M Y, Trojanowski, John Q

“…Objective Olfactory dysfunction is common in Alzheimer disease (AD) and other neurodegenerative diseases. Paired helical filament (PHF)-tau, -synuclein, and…”
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Brain insulin resistance demonstrated in Alzheimer's disease is closely associated with elevated IRS-1 pS and cognitive deficits by Talbot, Konrad, Wang, Hoau-Yan, Kazi, Hala, Han, Li-Ying, Bakshi, Kalindi, Wilson, Robert, Schneider, Julie, Bennett, David, Wolf, Bryan, Trojanowski, John, Arnold, Steven

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O4‐02‐01: Brain insulin resistance demonstrated in Alzheimer's disease is closely associated with elevated IRS‐1 pS and cognitive deficits by Talbot, Konrad, Wang, Hoau‐Yan, Kazi, Hala, Han, Li‐Ying, Bakshi, Kalindi, Wilson, Robert, Schneider, Julie, Bennett, David, Wolf, Bryan, Trojanowski, John, Arnold, Steven

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Characterization of olfactory bulb glomeruli in schizophrenia by Rioux, Lise, Gelber, Edward Isaac, Parand, Leila, Kazi, Hala Altaf, Yeh, Joannie, Wintering, Rebecca, Bilker, Warren, Arnold, Steven Edward

“…Olfactory deficits, observed in schizophrenia, may be associated with a disruption of synaptic transmission in the olfactory system. Using immunohistochemistry…”
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