Search Results - "Kazazis, D M"

Adhesomes: Specific Granules Containing Receptors for Laminin, C3bi/Fibrinogen, Fibronectin, and Vitronectin in Human Polymorphonuclear Leukocytes and Monocytes by Singer, Irwin I., Scott, Solomon, Kawka, Douglas W., Kazazis, Diana M.

“…We have localized several major extracellular matrix protein receptors in the specific granules of human polymorphonuclear (PMN) and monocytic leukocytes using…”
Get full text

Cell Surface Distribution of Fibronectin and Vitronectin Receptors Depends on Substrate Composition and Extracellular Matrix Accumulation by Singer, Irwin I., Scott, Solomon, Kawka, Douglas W., Kazazis, Diana M., Gailit, James, Ruoslahti, Erkki

“…We used antibodies against the alpha subunits of the human fibronectin receptor (FNR) and vitronectin receptor (VNR) to localize simultaneously FNR and VNR at…”
Get full text

In vivo Co-Distribution of Fibronectin and Actin Fibers in Granulation Tissue: Immunofluorescence and Electron Microscope Studies of the Fibronexus at the Myofibroblast Surface by Singer, Irwin I., Kawka, Douglas W., Kazazis, Diana M., Richard A. F. Clark

“…The fibronexus (FNX), a very close transmembrane association of individual extracellular fibronectin fibers and actin microfilaments, was found previously at…”
Get full text

Lovastatin, an Inhibitor of Cholesterol Synthesis, Induces Hydroxymethylglutaryl-coenzyme A Reductase Directly on Membranes of Expanded Smooth Endoplasmic Reticulum in Rat Hepatocytes by Singer, Irwin I., Scott, Solomon, Kazazis, Diana M., Huff, Jesse W.

“…Lovastatin is a potent competitive inhibitor of the rate-limiting enzyme of cholesterol synthesis, 3-hydroxy-3-methylglutaryl-coenzyme A reductase (NADPH)…”
Get full text

Hydroxymethylglutaryl-coenzyme A Reductase-Containing Hepatocytes are Distributed Periportally in Normal and Mevinolin-Treated Rat Livers by Singer, Irwin I., Kawka, Douglas W., Kazazis, Diana M., Alberts, Alfred W., Chen, Julie S., Huff, Jesse W., Ness, Gene C.

“…Mevinolin is a potent inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase; EC 1.1.1.34), an enzyme that catalyzes the rate-limiting…”
Get full text

Localization of the fibronexus at the surface of granulation tissue myofibroblasts using double-label immunogold electron microscopy on ultrathin frozen sections by Singer, I I, Kazazis, D M, Kawka, D W

“…An intimate transmembrane complex of fibronectin-containing extracellular fibers and actin microfilaments termed the fibronexus has been observed at the…”
Get more information

Scanning electron microscopy of focal contacts on the substratum attachment surface of fibroblasts adherent to fibronectin by SINGEER, I. I, KAZAKIS, D. M, SCOTT, S

“…We have examined the cell-to-substratum attachment surface of hamster fibroblasts with scanning EM, and describe the surface ultrastructure of focal contacts…”
Get full text

Nicarbazin complex yields dinitrocarbanilide as ultrafine crystals with improved anticoccidial activity by Rogers, E.F, Brown, R.D, Brown, J.E, Kazazis, D.M, Leanza, W.J

“…scanning electron microscopy revealed that micron-size crystals of nicarbazin disintegrate in water to form much smaller dinitrocarbanilide crystals, similar…”
Get full text

Optimal humanization of 1B4, an anti-CD18 murine monoclonal antibody, is achieved by correct choice of human V-region framework sequences by Singer, II, Kawka, DW, DeMartino, JA, Daugherty, BL, Elliston, KO, Alves, K, Bush, BL, Cameron, PM, Cuca, GC, Davies, P

“…The murine anti-CD18 mAb 1B4 has been humanized using CDR grafting. Three VH (Gal, Jon, and New) and two VL (Rei and Len) human frameworks, whose selection was…”
Get full text

Extracellular matrix-cytoskeletal interactions in rheumatoid arthritis. I. Immunoelectron microscopic analysis of the fibronexus at the adhesive surface of normal porcine type B synoviocytes in vitro by Singer, I I, Kazazis, D M, Kawka, D W, Rupp, E A, Bayne, E K

“…We studied cell surface interactions between the fibronectin (FN)-containing extracellular matrix and the actin cytoskeleton of normal porcine synoviocytes in…”
Get more information

Lovastatin, an inhibitor of cholesterol synthesis, induces hydroxymethylglutaryl-coenzyme A reductase directly on membranes of expanded smooth endoplasmic reticulum in rat hepatocytes by Singer, I I, Scott, S, Kazazis, D M, Huff, J W

“…Lovastatin is a potent competitive inhibitor of the rate-limiting enzyme of cholesterol synthesis, 3-hydroxy-3-methylglutaryl-coenzyme A reductase (NADPH)…”
Get full text

Lovastatin, an inhibitor of cholesterol synthesis, induces hydroxymethyltlutaryl-coenzyme A reductase directly on membranes of expanded smooth endoplasmic reticulum in rat hepatocytes by SINGER, I. I, SCOTT, S, KAZAZIS, D. M, HUFF, J. W

Get full text