Search Results - "Kaysheva, Anna L"
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Revelation of Proteomic Indicators for Colorectal Cancer in Initial Stages of Development
Published in Molecules (Basel, Switzerland) (31-01-2020)“…Colorectal cancer (CRC) at a current clinical level is still hardly diagnosed, especially with regard to nascent tumors, which are typically asymptotic…”
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2
Tear Proteome Revealed Association of S100A Family Proteins and Mesothelin with Thrombosis in Elderly Patients with Retinal Vein Occlusion
Published in International journal of molecular sciences (24-11-2022)“…Tear samples collected from patients with central retinal vein occlusion (CRVO; n = 28) and healthy volunteers (n = 29) were analyzed using a proteomic…”
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3
Sports Nutrition: Diets, Selection Factors, Recommendations
Published in Nutrients (25-10-2021)“…An athlete's diet is influenced by external and internal factors that can reduce or exacerbate exercise-induced food intolerance/allergy symptoms. This review…”
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Diversity of Plant Sterols Metabolism: The Impact on Human Health, Sport, and Accumulation of Contaminating Sterols
Published in Nutrients (01-05-2021)“…The way of plant sterols transformation and their benefits for humans is still a question under the massive continuing revision. In fact, there are no…”
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5
Food Intolerance: The Role of Histamine
Published in Nutrients (15-09-2021)“…Histamine is a natural amine derived from L-histidine. Although it seems that our knowledge about this molecule is wide and diverse, the importance of…”
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PowerNovo: de novo peptide sequencing via tandem mass spectrometry using an ensemble of transformer and BERT models
Published in Scientific reports (01-07-2024)“…The primary objective of analyzing the data obtained in a mass spectrometry-based proteomic experiment is peptide and protein identification, or correct…”
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Consolidation of metabolomic, proteomic, and GWAS data in connective model of schizophrenia
Published in Scientific reports (06-02-2023)“…Despite of multiple systematic studies of schizophrenia based on proteomics, metabolomics, and genome-wide significant loci, reconstruction of underlying…”
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Proteomic and molecular dynamic investigations of PTM-induced structural fluctuations in breast and ovarian cancer
Published in Scientific reports (29-09-2021)“…Post-translational processing leads to conformational changes in protein structure that modulate molecular functions and change the signature of metabolic…”
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9
Modeling Side Chains in the Three-Dimensional Structure of Proteins for Post-Translational Modifications
Published in International journal of molecular sciences (01-09-2023)“…Amino acid substitutions and post-translational modifications (PTMs) play a crucial role in many cellular processes by directly affecting the structural and…”
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10
PSSNet-An Accurate Super-Secondary Structure for Protein Segmentation
Published in International journal of molecular sciences (26-11-2022)“…A super-secondary structure (SSS) is a spatially unique ensemble of secondary structural elements that determine the three-dimensional shape of a protein and…”
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SAFoldNet: A Novel Tool for Discovering and Aligning Three-Dimensional Protein Structures Based on a Neural Network
Published in International journal of molecular sciences (01-10-2023)“…The development and improvement of methods for comparing and searching for three-dimensional protein structures remain urgent tasks in modern structural…”
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Molecular Modeling Insights into Upadacitinib Selectivity upon Binding to JAK Protein Family
Published in Pharmaceuticals (Basel, Switzerland) (25-12-2021)“…Rheumatoid arthritis (RA) is a chronic disease characterized by bone joint damage and incapacitation. The mechanism underlying RA pathogenesis is autoimmunity…”
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Metabolomic Markers for Predicting Preeclampsia in the First Trimester of Pregnancy: A Retrospective Study
Published in Molecules (Basel, Switzerland) (12-04-2022)“…We sought to identify the characteristic metabolite profile of blood plasma samples obtained from patients with preeclampsia. Direct high-resolution mass…”
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14
Current Approaches in Supersecondary Structures Investigation
Published in International journal of molecular sciences (02-11-2021)“…Proteins expressed during the cell cycle determine cell function, topology, and responses to environmental influences. The development and improvement of…”
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15
Atomic Simulation of the Binding of JAK1 and JAK2 with the Selective Inhibitor Ruxolitinib
Published in International journal of molecular sciences (09-09-2022)“…Rheumatoid arthritis belongs to the group of chronic systemic autoimmune diseases characterized by the development of destructive synovitis and extra-articular…”
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In Silico Study of the Interactions of Anle138b Isomer, an Inhibitor of Amyloid Aggregation, with Partner Proteins
Published in International journal of molecular sciences (17-12-2022)“…Herein, we aimed to highlight current "gaps" in the understanding of the potential interactions between the Anle138b isomer ligand, a promising agent for…”
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17
3β-Corner Stability by Comparative Molecular Dynamics Simulations
Published in International journal of molecular sciences (02-10-2022)“…This study explored the mechanisms by which the stability of super-secondary structures of the 3β-corner type autonomously outside the protein globule are…”
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Mass Spectrometric Identification of Proteins Enhanced by the Atomic Force Microscopy Immobilization Surface
Published in International journal of molecular sciences (04-01-2021)“…An approach to highly-sensitive mass spectrometry detection of proteins after surface-enhanced concentrating has been elaborated. The approach is based on a…”
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Detection of Circulating Serum microRNA/Protein Complexes in ASD Using Functionalized Chips for an Atomic Force Microscope
Published in Molecules (Basel, Switzerland) (02-10-2021)“…MicroRNAs, which circulate in blood, are characterized by high diagnostic value; in biomedical research, they can be considered as candidate markers of various…”
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Analysis of Structural Changes in the Protein near the Phosphorylation Site
Published in Biomolecules (Basel, Switzerland) (24-10-2023)“…Modification of the protein after synthesis (PTM) often affects protein function as supported by numerous studies. However, there is no consensus about the…”
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