Search Results - "Kayser, Andrew S."

Frontal Cortex and the Discovery of Abstract Action Rules by Badre, David, Kayser, Andrew S., D'Esposito, Mark

“…Although we often encounter circumstances with which we have no prior experience, we rapidly learn how to behave in these novel situations. Such adaptive…”
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Retrieval-constrained valuation: Toward prediction of open-ended decisions by Good, Maxwell, Kayser, Andrew S.

“…Real-world decisions are often open ended, with goals, choice options, or evaluation criteria conceived by decision-makers themselves. Critically, the quality…”
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The salience network causally influences default mode network activity during moral reasoning by CHIONG, Winston, WILSON, Stephen M, D'ESPOSITO, Mark, KAYSER, Andrew S, GROSSMAN, Scott N, POORZAND, Pardis, SEELEY, William W, MILLER, Bruce L, RANKIN, Katherine P

“…Large-scale brain networks are integral to the coordination of human behaviour, and their anatomy provides insights into the clinical presentation and…”
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Enhancing dopamine tone modulates global and local cortical perfusion as a function of COMT val158met genotype by Furman, Daniella J., Pappas, Ioannis, White, Robert L., Kayser, Andrew S., D'Esposito, Mark

“…The cognitive effects of pharmacologically enhancing cortical dopamine (DA) tone are variable across healthy human adults. It has been postulated that…”
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The functional anatomy of a perceptual decision in the human brain by Kayser, Andrew S, Buchsbaum, Bradley R, Erickson, Drew T, D'Esposito, Mark

“…Our ability to make rapid decisions based on sensory information belies the complexity of the underlying computations. Recently, "accumulator" models of…”
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Working memory, cortical dopamine tone, and frontoparietal brain recruitment in post-traumatic stress disorder: a randomized controlled trial by Westphal, Andrew J., Ballard, Michael E., Rodriguez, Nicholas, Vega, Taylor A., D’Esposito, Mark, Kayser, Andrew S.

“…Post-traumatic stress disorder (PTSD) leads to impairments in both cognitive and affective functioning. Animal work suggests that chronic stress reduces…”
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Neural representations of relevant and irrelevant features in perceptual decision making by Kayser, Andrew S, Erickson, Drew T, Buchsbaum, Bradley R, D'Esposito, Mark

“…Although perceptual decision making activates a network of brain areas involved in sensory, integrative, and motor functions, circuit activity can clearly be…”
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The neural representation of sensorimotor transformations in a human perceptual decision making network by Erickson, Drew T., Kayser, Andrew S.

“…Humans can quickly engage a neural network to transform complex visual stimuli into a motor response. Activity from a key region within this network, the…”
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Right inferior frontal cortex activity correlates with tolcapone responsivity in problem and pathological gamblers by Kayser, Andrew S, Vega, Taylor, Weinstein, Dawn, Peters, Jan, Mitchell, Jennifer M

“…Failures of self-regulation in problem and pathological gambling (PPG) are thought to emerge from failures of top-down control, reflected neurophysiologically…”
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Decomposing effects of time on task reveals an anteroposterior gradient of perceptual decision regions by Buchsbaum, Bradley R, Erickson, Drew T, Kayser, Andrew S

“…In perceptual decision making, the selection of an appropriate action depends critically on an organism's ability to use sensory inputs to accumulate evidence…”
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Connectivity-Defined Subdivisions of the Intraparietal Sulcus Respond Differentially to Abstraction during Decision-Making by Newton, Melissa, Cookson, Savannah L, D'Esposito, Mark, Kayser, Andrew S

“…The intraparietal sulcus (IPS) has been implicated in numerous functions that range from representation of visual stimuli to action planning, but its role in…”
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Oscillatory dynamics coordinating human frontal networks in support of goal maintenance by Voytek, Bradley, Kayser, Andrew S, Badre, David, Fegen, David, Chang, Edward F, Crone, Nathan E, Parvizi, Josef, Knight, Robert T, D'Esposito, Mark

“…Humans have a capacity for hierarchical cognitive control—the ability to simultaneously control immediate actions while holding more abstract goals in mind…”
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Improved normalization of lesioned brains via cohort‐specific templates by Pappas, Ioannis, Hector, Henrik, Haws, Kari, Curran, Brian, Kayser, Andrew S., D'Esposito, Mark

“…In MRI studies, spatial normalization is required to infer results at the group level. In the presence of a brain lesion, such as in stroke patients, the…”
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Dopamine, locus of control, and the exploration-exploitation tradeoff by Kayser, Andrew S, Mitchell, Jennifer M, Weinstein, Dawn, Frank, Michael J

“…Whether to continue to exploit a source of reward, or to search for a new one of potentially greater value, is a fundamental and underconstrained decision…”
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Perceptual and categorical decision making: goal-relevant representation of two domains at different levels of abstraction by Shankar, Swetha, Kayser, Andrew S

“…To date it has been unclear whether perceptual decision making and rule-based categorization reflect activation of similar cognitive processes and brain…”
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Augmenting Frontal Dopamine Tone Enhances Maintenance over Gating Processes in Working Memory by Furman, Daniella J, Zhang, Zhihao, Chatham, Christopher H, Good, Maxwell, Badre, David, Hsu, Ming, Kayser, Andrew S

“…The contents of working memory must be maintained in the face of distraction, but updated when appropriate. To manage these competing demands of stability and…”
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Varenicline decreases alcohol consumption in heavy-drinking smokers by Mitchell, Jennifer M., Teague, Candice H., Kayser, Andrew S., Bartlett, Selena E., Fields, Howard L.

“…Rationale Emerging evidence suggests that the α4β2 form of the nicotinic acetylcholine receptor (nAChR) modulates the rewarding effects of alcohol. The nAChR…”
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Dopamine, corticostriatal connectivity, and intertemporal choice by Kayser, Andrew S, Allen, Daicia C, Navarro-Cebrian, Ana, Mitchell, Jennifer M, Fields, Howard L

“…Value-based decisions optimize behavioral outcomes. Because delayed rewards are discounted, an increased tendency to choose smaller, immediate rewards can lead…”
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Dopamine, time perception, and future time perspective by Mitchell, Jennifer M., Weinstein, Dawn, Vega, Taylor, Kayser, Andrew S.

“…Rationale Impairment in time perception, a critical component of decision-making, represents a risk factor for psychiatric conditions including substance…”
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Functional imaging by Kayser, Andrew S

“…Functional imaging methodology has revolutionized our ability to understand brain-behavior relationships. In contrast with the static images obtained with…”
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