Search Results - "Kayo Yasuda"

The role of nutrition and oxidative stress as aging factors in Caenorhabditis elegans by Yasuda, Kayo, Miyazawa, Masaki, Ishii, Takamasa, Ishii, Naoaki

“…The molecular mechanism of aging, which has been a “black box” for many years, has been elucidated in recent years, and the nematode C. elegans, which is a…”
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Metabolic Biomarkers in Nematode C. elegans During Aging by Yanase, Sumino, Ishii, Takamasa, Yasuda, Kayo, Ishii, Naoaki

“…Changes in energy metabolism occur not only in diseases such as cancer but also in the normal development and aging processes of various organisms. These…”
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Oxidative stress induced inflammation initiates functional decline of tear production by Uchino, Yuichi, Kawakita, Tetsuya, Miyazawa, Masaki, Ishii, Takamasa, Onouchi, Hiromi, Yasuda, Kayo, Ogawa, Yoko, Shimmura, Shigeto, Ishii, Naoaki, Tsubota, Kazuo

“…Oxidative damage and inflammation are proposed to be involved in an age-related functional decline of exocrine glands. However, the molecular mechanism of how…”
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Streptococcus thermophilus extends lifespan through activation of DAF-16-mediated antioxidant pathway in Caenorhabditis elegans by Desaka, Natsumi, Ota, Chinatsu, Nishikawa, Hitomi, Yasuda, Kayo, Ishii, Naoaki, Bito, Tomohiro, Kishinaga, Yukio, Naito, Yuji, Higashimura, Yasuki

“…Streptococcus thermophilus bacteria, which are widely used as fermented starter for dairy production, exert various beneficial health effects. Nevertheless,…”
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Endogenous reactive oxygen species cause astrocyte defects and neuronal dysfunctions in the hippocampus: a new model for aging brain by Ishii, Takamasa, Takanashi, Yumi, Sugita, Koichi, Miyazawa, Masaki, Yanagihara, Rintaro, Yasuda, Kayo, Onouchi, Hiromi, Kawabe, Noboru, Nakata, Munehiro, Yamamoto, Yorihiro, Hartman, Phil S., Ishii, Naoaki

“…Summary The etiology of astrocyte dysfunction is not well understood even though neuronal defects have been extensively studied in a variety of neuronal…”
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Interaction between the ins/IGF-1 and p38 MAPK signaling pathways in molecular compensation of sod genes and modulation related to intracellular ROS levels in C. elegans by Yanase, Sumino, Yasuda, Kayo, Ishii, Naoaki

“…Superoxide dismutases, which catalytically remove intracellular superoxide radicals by the disproportionation of molecular oxygen and hydrogen peroxide, are…”
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Clinical practice guidance for next‐generation sequencing in cancer diagnosis and treatment (Edition 1.0) by Sunami, Kuniko, Takahashi, Hideaki, Tsuchihara, Katsuya, Takeda, Masayuki, Suzuki, Tatsuya, Naito, Yoichi, Sakai, Kazuko, Dosaka‐Akita, Hirotoshi, Ishioka, Chikashi, Kodera, Yasuhiro, Muto, Manabu, Wakai, Toshifumi, Yamazaki, Kentaro, Yasui, Wataru, Bando, Hideaki, Fujimoto, Yumi, Fukuoka, Shota, Harano, Kenichi, Kawazoe, Akihito, Kimura, Gen, Koganemaru, Shigehiro, Kogawa, Takahiro, Kotani, Daisuke, Kuboki, Yasutoshi, Matsumoto, Hiroshi, Matsumoto, Shingo, Mishima, Saori, Nakamura, Yoshiaki, Sawada, Kentaro, Shingaki, Sumito, Shitara, Kohei, Umemoto, Kumiko, Umemura, Shigeki, Yasuda, Kayo, Yoshino, Takayuki, Yamamoto, Noboru, Nishio, Kazuto

“…In Japan, the social (medical) health‐care system is on the way to being developed to advance personalized medicine through the implementation of cancer…”
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Model animals for the study of oxidative stress from complex II by Ishii, Takamasa, Miyazawa, Masaki, Onouchi, Hiromi, Yasuda, Kayo, Hartman, Phil S., Ishii, Naoaki

“…Mitochondria play a role of energy production and produce intracellular reactive oxygen species (ROS), especially superoxide anion (O2−) as a byproduct of…”
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Asymmetric Arginine Dimethylation Determines Life Span in C. elegans by Regulating Forkhead Transcription Factor DAF-16 by Takahashi, Yuta, Daitoku, Hiroaki, Hirota, Keiko, Tamiya, Hiroko, Yokoyama, Atsuko, Kako, Koichiro, Nagashima, Yusuke, Nakamura, Ayumi, Shimada, Takashi, Watanabe, Satoshi, Yamagata, Kazuyuki, Yasuda, Kayo, Ishii, Naoaki, Fukamizu, Akiyoshi

“…Arginine methylation is a widespread posttranslational modification of proteins catalyzed by a family of protein arginine methyltransferases (PRMTs). It is…”
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Reviewing the Effects of Skin Manipulations on Adult Newt Limb Regeneration: Implications for the Subcutaneous Origin of Axial Pattern Formation by Casco-Robles, Martin Miguel, Yasuda, Kayo, Yahata, Kensuke, Maruo, Fumiaki, Chiba, Chikafumi

“…Newts are unique salamanders that can regenerate their limbs as postmetamorphic adults. In order to regenerate human limbs as newts do, it is necessary to…”
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A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis by ISHII, Takamasa, YASUDA, Kayo, AKATSUKA, Akira, HINO, Okio, HARTMAN, Philip S, ISHII, Naoaki

“…Intracellular oxidative stress from mitochondria is thought to be important in carcinogenesis and tumorigenesis, but direct experimental proof is limited. In…”
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Correction: Oxidative stress induced inflammation initiates functional decline of tear production by Uchino, Yuichi, Kawakita, Tetsuya, Miyazawa, Masaki, Ishii, Takamasa, Onouchi, Hiromi, Yasuda, Kayo, Ogawa, Yoko, Shimmura, Shigeto, Ishii, Naoaki, Tsubota, Kazuo

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Genetically induced oxidative stress in mice causes thrombocytosis, splenomegaly and placental angiodysplasia that leads to recurrent abortion by Ishii, Takamasa, Miyazawa, Masaki, Takanashi, Yumi, Tanigawa, Maya, Yasuda, Kayo, Onouchi, Hiromi, Kawabe, Noboru, Mitsushita, Junji, Hartman, Phil S, Ishii, Naoaki

“…Historical data in the 1950s suggests that 7%, 11%, 33%, and 87% of couples were infertile by ages 30, 35, 40 and 45, respectively. Up to 22.3% of infertile…”
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A Defect in the Cytochrome b Large Subunit in Complex II Causes Both Superoxide Anion Overproduction and Abnormal Energy Metabolism in Caenorhabditis elegans by Senoo-Matsuda, Nanami, Yasuda, Kayo, Tsuda, Michio, Ohkubo, Tomoichi, Yoshimura, Shinichi, Nakazawa, Hiroe, Hartman, Philip S., Ishii, Naoaki

“…A mev-1(kn1) mutant of the nematode Caenorhabditis elegans is defective in the cytochrome b large subunit (Cyt-1/ceSDHC) in complex II of the mitochondrial…”
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Age-related changes of mitochondrial structure and function in Caenorhabditis elegans by Yasuda, Kayo, Ishii, Takamasa, Suda, Hitoshi, Akatsuka, Akira, Hartman, Philip S., Goto, Sataro, Miyazawa, Masaki, Ishii, Naoaki

“…A number of observations have been made to examine the role that mitochrondrial energetics and superoxide anion production play in the aging of wild-type…”
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Nuclear envelope localization of Ran-binding protein 2 and Ran-GTPase-activating protein 1 in psoriatic epidermal keratinocytes by Yasuda, Kayo, Sugiura, Kazumitsu, Takeichi, Takuya, Ogawa, Yasushi, Muro, Yoshinao, Akiyama, Masashi

“…The nuclear localization signal (NLS)‐containing proteins LEDGF and STAT3 localize to the nucleus in both the spinous and basal layers of the epidermis in…”
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Liposome-Encapsulated Hemoglobin Enhances Chemotherapy to Suppress Metastasis in Mice by Murayama, Chieko, Kawaguchi, Akira T., Kamijo, Akemi, Naito, Katsuko, Iwao, Kayoko, Tsukamoto, Hideo, Yasuda, Kayo, Nagato, Yasukazu

“…Liposome‐encapsulated hemoglobin with high O2‐affinity (P50O2 = 10 mm Hg, h‐LEH) was reported to enhance tumor radiosensitivity. We hypothesize that targeted…”
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The Role of Mitochondrial Superoxide Anion(O2-)on Physiological Aging in C57BL/6J Mice by Miyazawa, Masaki, Ishii, Takamasa, Yasuda, Kayo, Noda, Setsuko, Onouchi, Hiromi, Hartman, Philip S, Ishii, Naoaki

“…Much attention has been focused on the mitochondrial superoxide anion(O2-), which is also a critical free radial produced by ionizing radiation. The specific…”
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Mitochondrial reactive oxygen species generation by the SDHC V69E mutation causes low birth weight and neonatal growth retardation by Ishii, Takamasa, Miyazawa, Masaki, Onodera, Akira, Yasuda, Kayo, Kawabe, Noboru, Kirinashizawa, Mika, Yoshimura, Shinichi, Maruyama, Naoki, Hartman, Philip S, Ishii, Naoaki

“…We have previously demonstrated that excessive mitochondrial reactive oxygen species caused by mutations in the SDHC subunit of Complex II resulted in…”
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MRT letter: Expression of ATP sensor protein in Caenorhabditis elegans by Kishikawa, Jun-Ichi, Fujikawa, Makoto, Imamura, Hiromi, Yasuda, Kayo, Noji, Hiroyuki, Ishii, Naoaki, Mitani, Shohei, Yokoyama, Ken

“…Adenosine 5′‐triphosphate (ATP) is the major energy currency and is involved in many biological processes. The ATP‐monitoring system for cells in animals can…”
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