Search Results - "Kayali, Ghazi"

Robust antiviral activity of commonly prescribed antidepressants against emerging coronaviruses: in vitro and in silico drug repurposing studies by Kutkat, Omnia, Moatasim, Yassmin, Al‐Karmalawy, Ahmed A., Abulkhair, Hamada S., Gomaa, Mokhtar R., El-Taweel, Ahmed N., Abo Shama, Noura M., GabAllah, Mohamed, Mahmoud, Dina B., Kayali, Ghazi, Ali, Mohamed A., Kandeil, Ahmed, Mostafa, Ahmed

“…During the current coronavirus disease 2019 (COVID-19) pandemic, symptoms of depression are commonly documented among both symptomatic and asymptomatic…”
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EGYVIR: An immunomodulatory herbal extract with potent antiviral activity against SARS-CoV-2 by Roshdy, Wael H, Rashed, Helmy A, Kandeil, Ahmed, Mostafa, Ahmed, Moatasim, Yassmin, Kutkat, Omnia, Abo Shama, Noura M, Gomaa, Mokhtar R, El-Sayed, Ibrahim H, El Guindy, Nancy M, Naguib, Amal, Kayali, Ghazi, Ali, Mohamed A

“…Due to the challenges for developing vaccines in devastating pandemic situations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), developing…”
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FDA-Approved Drugs with Potent In Vitro Antiviral Activity against Severe Acute Respiratory Syndrome Coronavirus 2 by Mostafa, Ahmed, Kandeil, Ahmed, A M M Elshaier, Yaseen, Kutkat, Omnia, Moatasim, Yassmin, Rashad, Adel A, Shehata, Mahmoud, Gomaa, Mokhtar R, Mahrous, Noura, Mahmoud, Sara H, GabAllah, Mohamed, Abbas, Hisham, Taweel, Ahmed El, Kayed, Ahmed E, Kamel, Mina Nabil, Sayes, Mohamed El, Mahmoud, Dina B, El-Shesheny, Rabeh, Kayali, Ghazi, Ali, Mohamed A

“…(1) Background: Drug repositioning is an unconventional drug discovery approach to explore new therapeutic benefits of existing drugs. Currently, it emerges as…”
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Genetic characterization of highly pathogenic avian influenza A H5N8 viruses isolated from wild birds in Egypt by Kandeil, Ahmed, Kayed, Ahmed, Moatasim, Yassmin, Webby, Richard J, McKenzie, Pamela P, Kayali, Ghazi, Ali, Mohamed A

“…A newly emerged H5N8 influenza virus was isolated from green-winged teal in Egypt during December 2016. In this study, we provide a detailed characterization…”
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Avian Influenza A(H5N1) Virus in Egypt by Kayali, Ghazi, Kandeil, Ahmed, El-Shesheny, Rabeh, Kayed, Ahmed S, Maatouq, Asmaa M, Cai, Zhipeng, McKenzie, Pamela P, Webby, Richard J, El Refaey, Samir, Kandeel, Amr, Ali, Mohamed A

“…In Egypt, avian influenza A subtype H5N1 and H9N2 viruses are enzootic in poultry. The control plan devised by veterinary authorities in Egypt to prevent…”
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Bioactive Polyphenolic Compounds Showing Strong Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus 2 by Kandeil, Ahmed, Mostafa, Ahmed, Kutkat, Omnia, Moatasim, Yassmin, Al-Karmalawy, Ahmed A, Rashad, Adel A, Kayed, Ahmed E, Kayed, Azza E, El-Shesheny, Rabeh, Kayali, Ghazi, Ali, Mohamed A

“…Until now, there has been no direct evidence of the effectiveness of repurposed FDA-approved drugs against Severe Acute Respiratory Syndrome Coronavirus 2…”
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The species coalescent indicates possible bat and pangolin origins of the COVID-19 pandemic by Yang, Jialin, Skaro, Michael, Chen, Jiani, Zhan, Duna, Lyu, Leke, Gay, Skylar, Kandeil, Ahmed, Ali, Mohamed A., Kayali, Ghazi, Stoianova, Kateryna, Ji, Pensheng, Alabady, Magdy, Bahl, Justin, Liu, Liang, Arnold, Jonathan

“…A consensus species tree is reconstructed from 11 gene trees for human, bat, and pangolin beta coronaviruses from samples taken early in the pandemic (prior to…”
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Bat-borne H9N2 influenza virus evades MxA restriction and exhibits efficient replication and transmission in ferrets by Halwe, Nico Joel, Hamberger, Lea, Sehl-Ewert, Julia, Mache, Christin, Schön, Jacob, Ulrich, Lorenz, Calvelage, Sten, Tönnies, Mario, Fuchs, Jonas, Bandawane, Pooja, Loganathan, Madhumathi, Abbad, Anass, Carreño, Juan Manuel, Bermúdez-González, Maria C., Simon, Viviana, Kandeil, Ahmed, El-Shesheny, Rabeh, Ali, Mohamed A., Kayali, Ghazi, Budt, Matthias, Hippenstiel, Stefan, Hocke, Andreas C., Krammer, Florian, Wolff, Thorsten, Schwemmle, Martin, Ciminski, Kevin, Hoffmann, Donata, Beer, Martin

“…Influenza A viruses (IAVs) of subtype H9N2 have reached an endemic stage in poultry farms in the Middle East and Asia. As a result, human infections with avian…”
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Genesis of Influenza A(H5N8) Viruses by El-Shesheny, Rabeh, Barman, Subrata, Feeroz, Mohammed M, Hasan, M Kamrul, Jones-Engel, Lisa, Franks, John, Turner, Jasmine, Seiler, Patrick, Walker, David, Friedman, Kimberly, Kercher, Lisa, Begum, Sajeda, Akhtar, Sharmin, Datta, Ashis Kumar, Krauss, Scott, Kayali, Ghazi, McKenzie, Pamela, Webby, Richard J, Webster, Robert G

“…Highly pathogenic avian influenza A(H5N8) clade 2.3.4.4 virus emerged in 2016 and spread to Russia, Europe, and Africa. Our analysis of viruses from domestic…”
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Avian Influenza A(H5N1) and A(H9N2) Seroprevalence and Risk Factors for Infection Among Egyptians: A Prospective, Controlled Seroepidemiological Study by Gomaa, Mokhtar R., Kayed, Ahmed S., Elabd, Mona A., Zeid, Dina Abu, Zaki, Shaimaa A., El Rifay, Amira S., Sherif, Lobna S., McKenzie, Pamela P., Webster, Robert G., Webby, Richard J., Ali, Mohamed A., Kayali, Ghazi

“…A(H5N1) and A(H9N2) avian influenza viruses are enzootic in Egyptian poultry, and most A (H5N1) human cases since 2009 have occurred in Egypt. Our…”
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Incidence and Seroprevalence of Avian Influenza in a Cohort of Backyard Poultry Growers, Egypt, August 2015-March 2019 by Gomaa, Mokhtar R, El Rifay, Amira S, Abu Zeid, Dina, Elabd, Mona A, Elabd, Eman, Kandeil, Ahmed, Shama, Noura M Abo, Kamel, Mina N, Marouf, Mohamed A, Barakat, Ahmed, Refaey, Samir, Naguib, Amal, McKenzie, Pamela P, Webby, Richard J, Ali, Mohamed A, Kayali, Ghazi

“…Currently enzootic avian influenza H5N1, H9N2, and H5N8 viruses were introduced into poultry in Egypt in 2006, 2011, and 2016, respectively. Infections with…”
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Genetic and antigenic evolution of H9N2 avian influenza viruses circulating in Egypt between 2011 and 2013 by Kandeil, Ahmed, El-Shesheny, Rabeh, Maatouq, Asmaa M, Moatasim, Yassmin, Shehata, Mahmoud M, Bagato, Ola, Rubrum, Adam, Shanmuganatham, Karthik, Webby, Richard J, Ali, Mohamed Ahmed, Kayali, Ghazi

“…Avian influenza virus subtype H9N2 has been circulating in the Middle East since the 1990s. For uncertain reasons, H9N2 was not detected in Egyptian farms…”
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Active surveillance for avian influenza virus, Egypt, 2010-2012 by Kayali, Ghazi, Kandeil, Ahmed, El-Shesheny, Rabeh, Kayed, Ahmed S, Gomaa, Mokhtar M, Maatouq, Asmaa M, Shehata, Mahmoud M, Moatasim, Yassmin, Bagato, Ola, Cai, Zhipeng, Rubrum, Adam, Kutkat, Mohamed A, McKenzie, Pamela P, Webster, Robert G, Webby, Richard J, Ali, Mohamed A

“…Continuous circulation of influenza A(H5N1) virus among poultry in Egypt has created an epicenter in which the viruses evolve into newer subclades and continue…”
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Global Distribution and Molecular Evolution of Bat Coronaviruses by El Sayes, Mohamed, Badra, Rebecca, Ali, Mohamed A., El-Shesheny, Rabeh, Kayali, Ghazi

“…Bat coronaviruses cause a wide range of illnesses in humans and animals. Bats are known to harbor a wide diversity of Alphacoronaviruses and Betacoronaviruses…”
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Unlocking pandemic potential: prevalence and spatial patterns of key substitutions in avian influenza H5N1 in Egyptian isolates by Young, Sean G, Kitchen, Andrew, Kayali, Ghazi, Carrel, Margaret

“…Avian influenza H5N1 has a high human case fatality rate, but is not yet well-adapted to human hosts. Amino acid substitutions currently circulating in avian…”
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Incidence and neutralizing antibody seroprevalence of influenza B virus in Egypt: Results of a community-based cohort study by Abo Shama, Noura M, Mahmoud, Sara H, Bagato, Ola, AbdElsalam, Elsayed Tarek, Alkhazindar, Maha, Kandeil, Ahmed, McKenzie, Pamela P, Webby, Richard J, Ali, Mohamed A, Kayali, Ghazi, El-Shesheny, Rabeh

“…Since 2000, two lineages of influenza B viruses, Victoria and Yamagata, have been circulating at similar frequencies worldwide. Little is known about the…”
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Cross-species spill-over potential of the H9N2 bat influenza A virus by El-Shesheny, Rabeh, Franks, John, Kandeil, Ahmed, Badra, Rebecca, Turner, Jasmine, Seiler, Patrick, Marathe, Bindumadhav M., Jeevan, Trushar, Kercher, Lisa, Hu, Meng, Sim, Yul Eum, Hui, Kenrie P. Y., Chan, Michael C. W., Thompson, Andrew J., McKenzie, Pamela, Govorkova, Elena A., Russell, Charles J., Vogel, Peter, Paulson, James C., Peiris, J. S. Malik, Webster, Robert G., Ali, Mohamed A., Kayali, Ghazi, Webby, Richard J.

“…In 2017, a novel influenza A virus (IAV) was isolated from an Egyptian fruit bat. In contrast to other bat influenza viruses, the virus was related to avian…”
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Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt by El Taweel, Ahmed, Kandeil, Ahmed, Barakat, Ahmed, Alfaroq Rabiee, Omar, Kayali, Ghazi, Ali, Mohamed Ahmed

“…Astroviruses belong to family which includes two main genera: Mamastroviruses that infect mammals, and Avastroviruses that infect avian hosts. Bats and wild…”
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Molecular characterization of avian influenza H5N1 virus in Egypt and the emergence of a novel endemic subclade by El-Shesheny, Rabeh, Kandeil, Ahmed, Bagato, Ola, Maatouq, Asmaa M, Moatasim, Yassmin, Rubrum, Adam, Song, Min-Suk, Webby, Richard J, Ali, Mohamed Ahmed, Kayali, Ghazi

“…Clade 2.2 highly pathogenic H5N1 viruses have been in continuous circulation in Egyptian poultry since 2006. Their persistence caused significant genetic drift…”
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Egyptian Fruit Bats ( Rousettus aegyptiacus ) Were Resistant to Experimental Inoculation with Avian-Origin Influenza A Virus of Subtype H9N2, But Are Susceptible to Experimental Infection with Bat-Borne H9N2 Virus by Halwe, Nico Joel, Gorka, Marco, Hoffmann, Bernd, Rissmann, Melanie, Breithaupt, Angele, Schwemmle, Martin, Beer, Martin, Kandeil, Ahmed, Ali, Mohamed A, Kayali, Ghazi, Hoffmann, Donata, Balkema-Buschmann, Anne

“…Influenza A viruses (IAV) of subtype H9N2, endemic in world-wide poultry holdings, are reported to cause spill-over infections to pigs and humans and have also…”
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