Search Results - "Kay O. Johswich"

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  1. 1

    In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa by Johswich, Kay O, McCaw, Shannon E, Islam, Epshita, Sintsova, Anna, Gu, Angel, Shively, John E, Gray-Owen, Scott D

    Published in PLoS pathogens (01-07-2013)
    “…Neisseria meningitidis (Nme) asymptomatically colonizes the human nasopharynx, yet can initiate rapidly-progressing sepsis and meningitis in rare instances…”
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    Journal Article
  2. 2

    Distinct roles of the anaphylatoxin receptors C3aR, C5aR1 and C5aR2 in experimental meningococcal infections by Muenstermann, Marcel, Strobel, Lea, Klos, Andreas, Wetsel, Rick A., Woodruff, Trent M., Köhl, Jörg, Johswich, Kay O.

    Published in Virulence (01-01-2019)
    “…The complement system is pivotal in the defense against invasive disease caused by Neisseria meningitidis (Nme, meningococcus), particularly via the membrane…”
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    Journal Article
  3. 3

    Invasive Potential of Nonencapsulated Disease Isolates of Neisseria meningitidis by JOHSWICH, Kay O, JIANWEI ZHOU, LAW, Dennis K. S, MICHAEL, Frank St, MCCAW, Shannon E, JAMIESON, Frances B, COX, Andrew D, TSANG, Raymond S. W, GRAY-OWEN, Scott D

    Published in Infection and Immunity (01-07-2012)
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    Journal Article
  4. 4

    Anticoagulants impact on innate immune responses and bacterial survival in whole blood models of Neisseria meningitidis infection by Strobel, Lea, Johswich, Kay O.

    Published in Scientific reports (05-07-2018)
    “…Neisseria meningitidis (meningococcus) causes invasive diseases such as meningitis or septicaemia. Ex vivo infection of human whole blood is a valuable tool to…”
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    Journal Article
  5. 5

    Complement C5a Receptor 1 Exacerbates the Pathophysiology of N. meningitidis Sepsis and Is a Potential Target for Disease Treatment by Herrmann, Johannes B, Muenstermann, Marcel, Strobel, Lea, Schubert-Unkmeir, Alexandra, Woodruff, Trent M, Gray-Owen, Scott D, Klos, Andreas, Johswich, Kay O

    Published in mBio (23-01-2018)
    “…Sepsis caused by (meningococcus) is a rapidly progressing, life-threatening disease. Because its initial symptoms are rather unspecific, medical attention is…”
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    Journal Article
  6. 6

    Differential influences of complement on neutrophil responses to Neisseria meningitidis infection by Krüger, Sören, Eichler, Emma, Strobel, Lea, Schubert-Unkmeir, Alexandra, Johswich, Kay O

    Published in Pathogens and disease (01-11-2018)
    “…The complement system is the primary innate immune determinant protecting against invasive diseases caused by the Gram-negative bacterium Neisseria…”
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    Journal Article
  7. 7

    A native outer membrane vesicle vaccine confers protection against meningococcal colonization in human CEACAM1 transgenic mice by Pajon, Rolando, Buckwalter, Carolyn M, Johswich, Kay O, Gray-Owen, Scott D, Granoff, Dan M

    Published in Vaccine (10-03-2015)
    “…Highlights • Human CEACAM1 transgenic mice were immunized with native meningococcal OMV vaccines with attenuated endotoxin and over-expressed FHbp. • The mice…”
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    Journal Article
  8. 8

    Sterilizing immunity elicited by Neisseria meningitidis carriage shows broader protection than predicted by serum antibody cross-reactivity in CEACAM1-humanized mice by Johswich, Kay O, McCaw, Shannon E, Strobel, Lea, Frosch, Matthias, Gray-Owen, Scott D

    Published in Infection and immunity (01-01-2015)
    “…Neisseria meningitidis asymptomatically colonizes the human upper respiratory tract but is also the cause of meningitis and severe septicemia. Carriage or…”
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    Journal Article
  9. 9

    In Vivo Adaptation and Persistence of Neisseria meningitidis within the Nasopharyngeal Mucosa: e1003509 by Johswich, Kay O, McCaw, Shannon E, Islam, Epshita, Sintsova, Anna, Gu, Angel, Shively, John E, Gray-Owen, Scott D

    Published in PLoS pathogens (01-07-2013)
    “…Neisseria meningitidis (Nme) asymptomatically colonizes the human nasopharynx, yet can initiate rapidly-progressing sepsis and meningitis in rare instances…”
    Get full text
    Journal Article
  10. 10

    Complement C5a Receptor 1 Exacerbates the Pathophysiology of italic toggle="yes">N. meningitidis /italic> Sepsis and Is a Potential Target for Disease Treatment by Johannes B. Herrmann, Marcel Muenstermann, Lea Strobel, Alexandra Schubert-Unkmeir, Trent M. Woodruff, Scott D. Gray-Owen, Andreas Klos, Kay O. Johswich

    Published in mBio (01-03-2018)
    “…ABSTRACT Sepsis caused by Neisseria meningitidis (meningococcus) is a rapidly progressing, life-threatening disease. Because its initial symptoms are rather…”
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    Journal Article