Search Results - "Kayır, Hakan"

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  1. 1

    Clozapine Increases Nestin Concentration in the Adult Male Rat Hippocampus: A Preliminary Study by Kayir, Hakan, Jenkins, Bryan W, Alural, Begüm, Khokhar, Jibran Y

    “…Patients with schizophrenia, and rodent models of the disease, both exhibit suppressed neurogenesis, with antipsychotics possibly enhancing neurogenesis in…”
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  2. 2

    Baseline impulsive choice predicts the effects of nicotine and nicotine withdrawal on impulsivity in rats by Kayir, Hakan, Semenova, Svetlana, Markou, Athina

    “…Impulsive choice, a form of impulsivity, is associated with tobacco smoking in humans. Trait impulsivity may be a vulnerability factor for smoking, or smoking…”
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  3. 3

    Plasma essential amino acid levels in first episode psychosis at baseline and after antipsychotic treatment by Garip, Beyazit, Khokhar, Jibran Y., Kayir, Hakan

    Published in NPJ schizophrenia (06-11-2024)
    “…This study assessed plasma levels of essential amino acids (EAA) in drug-naïve first episode psychosis (FEP) patients at diagnosis and after 10 weeks of…”
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  4. 4

    Effects of pioglitazone and retinoic acid in a rotenone model of Parkinson's disease by Ulusoy, Gokhan K, Celik, Turgay, Kayir, Hakan, Gürsoy, Murat, Isik, Ahmet T, Uzbay, Tayfun I

    Published in Brain research bulletin (15-07-2011)
    “…Highlights ► Parkinson disease (PD) is a neurodegenerative disorder of unknown etiology. ► The study investigates the effects of antioxidants on…”
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  5. 5

    Discordant Effects of Cannabinoid 2 Receptor Antagonism/Inverse Agonism During Adolescence on Pavlovian and Instrumental Reward Learning in Adult Male Rats by Ellner, Danna, Hallam, Bryana, Frie, Jude A., Thorpe, Hayley H. A., Shoaib, Muhammad, Kayir, Hakan, Jenkins, Bryan W., Khokhar, Jibran Y.

    Published in Frontiers in synaptic neuroscience (30-08-2021)
    “…The endocannabinoid system is responsible for regulating a spectrum of physiological activities and plays a critical role in the developing brain. During…”
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  6. 6

    Alteration in NMDAR‐related amino acids in first episode psychosis by Garip, Beyazit, Kayir, Hakan

    Published in Synapse (New York, N.Y.) (01-11-2019)
    “…The aim of the present study was to explore the role of N‐methyl‐D‐aspartate receptor (NMDAR) related amino acids in drug‐naive first episode psychosis (FEP)…”
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  7. 7

    Evidence for the role of nitric oxide in nicotine-induced locomotor sensitization in mice by ULUSU, Umut, UZBAY, I. Tayfun, KAYIR, Hakan, ALICI, Tevfik, KARAKAS, Sirel

    Published in Psychopharmacologia (01-04-2005)
    “…Nitric oxide (NO) is implicated in both acute effects of addictive drugs and development of dependence to them. We investigated the role of NO in…”
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    l-Arginine metabolism before and after 10 weeks of antipsychotic treatment in first-episode psychotic patients by Garip, Beyazit, Kayir, Hakan, Uzun, Ozcan

    Published in Schizophrenia research (01-04-2019)
    “…Agmatine is an endogenous NMDA (N-methyl-d-aspartate) antagonist which is synthesized from l-Arginine and described as a novel neurotransmitter. Agmatine is…”
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  10. 10

    Effects of chronic ethanol administration and ethanol withdrawal on cyclic guanosine 3′,5′-monophosphate (cGMP) levels in the rat brain by Uzbay, İ.Tayfun, Çelik, Turgay, Aydın, Ahmet, Kayir, Hakan, Tokgöz, Serhat, Bilgi, Cumhur

    Published in Drug and alcohol dependence (09-04-2004)
    “…The main objective of the present study is to investigate the possible effects of chronic ethanol consumption and ethanol withdrawal on cyclic guanosine 3′,…”
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  11. 11

    Evaluation of rational pharmacotheraphy training performed in GMMA: comparison of pre- and posttraining by Ulusoy, Gökhan Kemal, Kayır, Hakan, Hüsamettin Gül, Seyrek, Melik, Yeşilyurt, Özgür, Yıldız, Oğuzhan, Çelik, Turgay

    Published in Gülhane tıp dergisi (01-03-2014)
    “…Rational use of medicines (pharmacotherapy) is defined by WHO as “patients receive the appropriate medicine, in proper dose, for an adequate period of time and…”
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  12. 12

    Sex Differences in the Neural and Behavioral Effects of Acute High-Dose Edible Cannabis Consumption in Rats by Quansah Amissah, Richard, Kayir, Hakan, Talhat, Malik Asfandyaar, Hassan, Ahmad, Gu, Yu, Johnson, Ron, Urban, Karolina, Khokhar, Jibran Y

    “…The consumption of Δ -tetrahydrocannabinol (THC)- or cannabis-containing edibles has increased in recent years; however, the behavioral and neural circuit…”
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  13. 13

    Effects of harman and harmine on naloxone-precipitated withdrawal syndrome in morphine-dependent rats by Aricioglu-Kartal, Feyza, Kayır, Hakan, Tayfun Uzbay, I

    Published in Life sciences (1973) (19-09-2003)
    “…The effects of the beta-carbolines, harman and harmine, on naloxone-precipitated withdrawal syndrome in morphine-dependent rats were investigated. Two morphine…”
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  14. 14

    Chronic Heavy Ethanol Consumption Is Associated with Decreased Platelet Aggregation in Rats by Baysan, Oben, Kaptan, Kürsat, Erinç, Kürsad, Öztas, Yesim, Coskun, Tayibe, Kayir, Hakan, Uzun, Mehmet, Uzbay, Tayfun, Beyan, Cengiz, Isik, Ersoy

    “…Although moderate alcohol consumption seems to be protective against atherosclerosis, coronary artery disease rate increases with its higher doses. Platelet…”
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  15. 15

    Nitric oxide synthase inhibition blocks amphetamine-induced locomotor activity in mice by Çelik, Turgay, Zaglı́, Ünal, Kayı́r, Hakan, Uzbay, I.Tayfun

    Published in Drug and alcohol dependence (01-09-1999)
    “…Effects of N G-nitroarginine methyl ester ( l-NAME), a nonspecific inhibitor of nitric oxide (NO) synthase, on amphetamine-induced locomotor activity were…”
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  16. 16

    Increased plasma agmatine levels in patients with schizophrenia by Uzbay, Tayfun, Goktalay, Gokhan, Kayir, Hakan, Eker, Salih S, Sarandol, Asli, Oral, Sema, Buyukuysal, Levent, Ulusoy, Gokhan, Kirli, Selcuk

    Published in Journal of psychiatric research (01-08-2013)
    “…Abstract Agmatine is an endogenous substance, synthesized from l -arginine, and it is proposed to be a new neurotransmitter. Preclinical studies indicated that…”
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  17. 17

    Bromocriptine and quinpirole, but not 7-OH-DPAT or SKF 38393, potentiate the inhibitory effect of L-NAME on ethanol-induced locomotor activity in mice by Uzbay, I Tayfun, Kayir, Hakan

    “…The effects of N(G)-nitro- l-arginine methyl ester (L-NAME), a nitric oxide synthase inhibitor, SKF 38393, bromocriptine (BRM), quinpirole (QPR) and…”
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    Agmatine blocks ethanol-induced locomotor hyperactivity in male mice by Ozden, Onder, Kayir, Hakan, Ozturk, Yusuf, Uzbay, Tayfun

    Published in European journal of pharmacology (20-05-2011)
    “…Ethanol-induced locomotor activity is associated to rewarding effects of ethanol and ethanol dependence. Agmatine is a novel endogenous ligand at α…”
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  20. 20

    The Relationship Between Cannabis, Cognition, and Schizophrenia: It's Complicated by Kayir, Hakan, Ruffolo, Jessica, McCunn, Patrick, Khokhar, Jibran Y

    “…The consequences of cannabis use, especially in the context of schizophrenia, have gained increased importance with the legalization of cannabis in North…”
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