Search Results - "Kay, Jarren C."

Mice from lines selectively bred for voluntary exercise are not more resistant to muscle injury caused by either contusion or wheel running by Kay, Jarren C, Colbath, James, Talmadge, Robert J, Garland, Jr, Theodore

“…Muscle injury can be caused by strenuous exercise, repetitive tasks or external forces. Populations that have experienced selection for high locomotor activity…”
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Identification of an integrated stress and growth response signaling switch that directs vertebrate intestinal regeneration by Westfall, Aundrea K, Perry, Blair W, Kamal, Abu H M, Hales, Nicole R, Kay, Jarren C, Sapkota, Madhab, Schield, Drew R, Pellegrino, Mark W, Secor, Stephen M, Chowdhury, Saiful M, Castoe, Todd A

“…Snakes exhibit extreme intestinal regeneration following months-long fasts that involves unparalleled increases in metabolism, function, and tissue growth, but…”
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In vivo regulation of brain-derived neurotrophic factor in dorsal root ganglia is mediated by nerve growth factor-triggered Akt activation during cystitis by Qiao, Li-Ya, Yu, Sharon J, Kay, Jarren C, Xia, Chun-Mei

“…The role of brain-derived neurotrophic factor (BDNF) in sensory hypersensitivity has been suggested; however the molecular mechanisms and signal transduction…”
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Activation of Extracellular Signal-Regulated Protein Kinase 5 is Essential for Cystitis- and Nerve Growth Factor-Induced Calcitonin Gene-Related Peptide Expression in Sensory Neurons by Yu, Sharon J, Xia, Chun-Mei, Kay, Jarren C, Qiao, Li-Ya

“…Background: Cystitis causes considerable neuronal plasticity in the primary afferent pathways. The molecular mechanism and signal transduction underlying cross…”
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Endogenous BDNF augments NMDA receptor phosphorylation in the spinal cord via PLCγ, PKC, and PI3K/Akt pathways during colitis by Liu, Miao, Kay, Jarren C, Shen, Shanwei, Qiao, Li-Ya

“…Spinal central sensitization is an important process in the generation and maintenance of visceral hypersensitivity. The release of brain-derived neurotrophic…”
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Single-cell resolution of intestinal regeneration in pythons without crypts illuminates conserved vertebrate regenerative mechanisms by Westfall, Aundrea K, Gopalan, Siddharth S, Kay, Jarren C, Tippetts, Trevor S, Cervantes, Margaret B, Lackey, Kimberly, Chowdhury, Saiful M, Pellegrino, Mark W, Castoe, Todd A

“…Canonical models of intestinal regeneration emphasize the critical role of the crypt stem cell niche to generate enterocytes that migrate to villus ends…”
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Effects of early-life exposure to Western diet and voluntary exercise on adult activity levels, exercise physiology, and associated traits in selectively bred High Runner mice by Cadney, Marcell D., Hiramatsu, Layla, Thompson, Zoe, Zhao, Meng, Kay, Jarren C., Singleton, Jennifer M., Albuquerque, Ralph Lacerda de, Schmill, Margaret P., Saltzman, Wendy, Garland, Theodore

“…•Subjects were selectively bred High Runner (HR) and non-selected Control (C) mice.•Juveniles were housed with/without wheels and given standard or Western…”
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Modest Regulation of Digestive Performance Is Maintained through Early Ontogeny for the American Alligator, Alligator mississippiensis by Kay, Jarren C, Elsey, Ruth M, Secor, Stephen M

“…The American alligator, , is an opportunistic carnivore that experiences an ontogenetic shift in food and feeding habits with an increase in body size…”
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Electrocardiograms of mice selectively bred for high levels of voluntary exercise: Effects of short-term exercise training and the mini-muscle phenotype by Kay, Jarren C., Claghorn, Gerald C., Thompson, Zoe, Hampton, Thomas G., Garland, Theodore

“…Changes in cardiac function that occur with exercise training have been studied in detail, but those accompanying evolved increases in the duration or…”
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Reduced non-bicarbonate skeletal muscle buffering capacity in mice with the mini-muscle phenotype by Kay, Jarren C, Ramirez, Jocelyn, Contreras, Erick, Garland, Jr, Theodore

“…Muscle pH decreases during exercise, which may impair function. Endurance training typically reduces muscle buffering capacity due to changes in fiber type…”
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Maternal exposure to Western diet affects adult body composition and voluntary wheel running in a genotype-specific manner in mice by Hiramatsu, Layla, Kay, Jarren, Thompson, Zoe, Singleton, Jennifer, Claghorn, Gerald, de Albuquerque, Ralph Lacerda, Ho, Brittany, Ho, Brett, Sanchez, Gabriela, Garland, Theodore

“…Abstract Some human diseases, including obesity, Type II diabetes, and numerous cancers, are thought to be influenced by environments experienced in early…”
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Selective Breeding and Short-Term Access to a Running Wheel Alter Stride Characteristics in House Mice by Claghorn, Gerald C., Thompson, Zoe, Kay, Jarren C., Ordonez, Genesis, Hampton, Thomas G., Garland, Theodore

“…Postural and kinematic aspects of running may have evolved to support high runner (HR) mice to run approximately threefold farther than control mice. Mice from…”
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Endogenous PI3K/Akt and NMDAR act independently in the regulation of CREB activity in lumbosacral spinal cord in cystitis by Kay, Jarren C., Xia, Chun-Mei, Liu, Miao, Shen, Shanwei, Yu, Sharon J., Chung, Chulwon, Qiao, Li-Ya

“…The integral interaction of signaling components in the regulation of visceral inflammation-induced central sensitization in the spinal cord has not been well…”
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Conditioned place preference for cocaine and methylphenidate in female mice from lines selectively bred for high voluntary wheel‐running behavior by Schmill, Margaret P., Cadney, Marcell D., Thompson, Zoe, Hiramatsu, Layla, Albuquerque, Ralph L., McNamara, Monica P., Castro, Alberto A., Kay, Jarren C., Buenaventura, Darrius G., Ramirez, Jocelyn L., Rhodes, Justin S., Garland, Theodore

“…Behavioral addictions can come in many forms, including overeating, gambling and overexercising. All addictions share a common mechanism involving activation…”
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Mice from lines selectively bred for voluntary exercise are not more resistant to muscle injury caused by either contusion or wheel running by Jarren C. Kay, James Colbath, Robert J. Talmadge, Theodore Garland

“…Muscle injury can be caused by strenuous exercise, repetitive tasks or external forces. Populations that have experienced selection for high locomotor activity…”
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Endogenous BDNF augments NMDA receptor phosphorylation in the spinal cord via PLC[gamma], PKC, and PI3K/Akt pathways during colitis by Liu, Miao, Kay, Jarren C, Shen, Shanwei, Qiao, Li-Ya

“…Background Spinal central sensitization is an important process in the generation and maintenance of visceral hypersensitivity. The release of brain-derived…”
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Inflammation and activity augment brain-derived neurotrophic factor peripheral release by Qiao, L.Y, Shen, S, Liu, M, Xia, C, Kay, J.C, Zhang, Q.L

“…Highlights • Depolarization evoked BDNF release to nerve terminals. • BDNF released to the visceral organ in vivo. • Both BDNF and pro-BDNF content were…”
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Conditioned Place Preference of Mice Selectively Bred for High Voluntary Wheel Running by Schmill, Margaret P., Cadney, Marcell D., Hiramatsu, Layla, Albuquerque, Ralph, Buenaventura, Darrius G., Louis, Monica P., Castro, Alberto A., Thompson, Zoe, Kay, Jarren C., Ramirez, Jocelyn L., Garland, Theodore

“…Running acts as a natural reward and shares features with other rewarding behaviors, such as eating or taking drugs of abuse. Exercise is even proposed to have…”
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Pituitary Adenylate Cyclase‐Activating Peptide (PACAP) and Substance P (SP) induce the release of Brain‐Derived Neurotropic Factor (BDNF) from the longitudinal muscle layer of the intestine by Alqudah, Mohammad, Mahavadi, Sunila, Zachary, Bradley L., Kay, Jarren C., Murthy, Karnam S, Grider, John R

“…BDNF has been implicated in neuronal development and plasticity. While BDNF is expressed in neural and non‐neuronal cells, the expression and secretion of BDNF…”
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Up‐regulation of phospho‐Akt in lumbosacral spinal cord during cystitis by Kay, Jarren C, Bradley, Zachary L, Xia, Chun‐Mei, Yu, Sharon J, Qiao, Li‐Ya

“…Central sensitization in the spinal cord is postulated to underlie the development of inflammation‐induced hypersensitivity. The protein kinase B/Akt is…”
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