Search Results - "Kay, G."
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1
Using an accelerated junctional rhythm to predict the success and safety of slow AV nodal pathway ablation
Published in Journal of cardiovascular electrophysiology (01-07-2021)Get full text
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2
Distribution, dynamics and functional roles of phosphatidylserine within the cell
Published in Cell communication and signaling (15-10-2019)“…Phosphatidylserine (PtdSer), an essential constituent of eukaryotic membranes, is the most abundant anionic phospholipid in the eukaryotic cell accounting for…”
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2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society
Published in Journal of the American College of Cardiology (02-10-2018)“…ACC/AHA Task Force Members Glenn N. Levine, MD, FACC, FAHA, Chair Patrick T. O’Gara, MD, MACC, FAHA, Chair-Elect Jonathan L. Halperin, MD, FACC, FAHA,…”
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4
Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival
Published in Proceedings of the National Academy of Sciences - PNAS (19-04-2016)“…Inhibition of the vascular endothelial growth factor (VEGF) pathway has failed to improve overall survival of patients with glioblastoma (GBM). We previously…”
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2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society
Published in Journal of the American College of Cardiology (02-10-2018)“…ACC/AHA Task Force Members Glenn N. Levine, MD, FACC, FAHA, Chair Patrick T. O’Gara, MD, MACC, FAHA, Chair-Elect Jonathan L. Halperin, MD, FACC, FAHA,…”
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6
Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases
Published in EMBO molecular medicine (01-11-2016)“…Anti‐angiogenic therapies using biological molecules that neutralize vascular endothelial growth factor‐A (VEGF‐A) have revolutionized treatment of retinal…”
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7
Can positron emission tomography help stratify the risk of sudden cardiac death in patients with hypertrophic cardiomyopathy?
Published in Journal of nuclear cardiology (01-08-2019)Get full text
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8
Mesenchymal Stem Cell-Conditioned Medium Reduces Disease Severity and Immune Responses in Inflammatory Arthritis
Published in Scientific reports (21-12-2017)“…We evaluated the therapeutic potential of mesenchymal stem cell-conditioned medium (CM-MSC) as an alternative to cell therapy in an antigen-induced model of…”
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Idiopathic Ventricular Arrhythmias Originating From the Left Ventricular Summit: Anatomic Concepts Relevant to Ablation
Published in Circulation. Arrhythmia and electrophysiology (01-12-2010)“…BACKGROUND—The summit of the left ventricle (LV) is the most superior portion of the epicardial LV bounded by an arc from the left anterior descending coronary…”
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10
Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies
Published in Proceedings of the National Academy of Sciences - PNAS (05-07-2011)“…We describe a generic approach to assemble correctly two heavy and two light chains, derived from two existing antibodies, to form human bivalent bispecific…”
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11
Phosphatidylserine dynamics in cellular membranes
Published in Molecular biology of the cell (01-06-2012)“…Much has been learned about the role of exofacial phosphatidylserine (PS) in apoptosis and blood clotting using annexin V. However, because annexins are…”
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12
Progranulin gene delivery protects dopaminergic neurons in a mouse model of Parkinson's disease
Published in PloS one (07-05-2014)“…Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by tremor, rigidity and akinesia/bradykinesia resulting from the progressive…”
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13
Preserving cognitive function for patients with overactive bladder: evidence for a differential effect with darifenacin
Published in International journal of clinical practice (Esher) (01-11-2008)“…Antimuscarinic agents used in the treatment of overactive bladder (OAB) differ in their potential to impair cognitive function. It is hypothesised that low…”
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14
2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias
Published in Europace (London, England) (01-08-2019)“…Ventricular arrhythmias are an important cause of morbidity and mortality and come in a variety of forms, from single premature ventricular complexes to…”
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15
Self-assembled low-molecular-weight gelator injectable microgel beads for delivery of bioactive agents
Published in Chemical science (Cambridge) (02-02-2021)“…We report the preparation of hybrid self-assembled microgel beads by combining the low molecular weight gelator (LMWG) DBS-CONHNH 2 and the natural…”
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16
Wide QRS Complex After Catheter Ablation
Published in Circulation (New York, N.Y.) (10-04-2018)Get full text
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A Novel Electrocardiographic Criterion for Differentiating a Left from Right Ventricular Outflow Tract Tachycardia Origin: The V2S/V3R Index
Published in Journal of cardiovascular electrophysiology (01-07-2014)“…V2S/V3R Index Distinguishes LVOT from RVOT Origins Introduction Although several ECG criteria have been proposed for differentiating between left and right…”
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Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis
Published in Nature communications (09-11-2017)“…The plasma membrane is uniquely enriched in phosphatidylserine (PtdSer). This anionic phospholipid is restricted almost exclusively to the inner leaflet of the…”
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Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery
Published in Cell reports (Cambridge) (05-02-2019)“…Bariatric surgery is widely used to treat obesity and improves type 2 diabetes beyond expectations from the degree of weight loss. Elevated post-prandial…”
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2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: Executive summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society
Published in Heart rhythm (01-10-2018)Get full text
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